Article
Multidisciplinary Sciences
Pierre Stahl, Kai Dang, Clair Vandersteen, Nicolas Guevara, Maureen Clerc, Dan Gnansia
Summary: This study provides a first characterization of the current distribution in the Oticon Medical cochlear implants using a stimulation mode called Distributed All-Polar (DAP). The results show that about 20% of the current returns to the extracochlear reference electrode, while the remaining 80% is distributed between intracochlear electrodes. The position of the stimulating electrode and the charge level affect the current distribution.
Article
Engineering, Biomedical
Leanne Sijgers, Alexander Huber, Sonia Tabibi, Julian Grosse, Christof Roeoesli, Patrick Boyle, Kanthaiah Koka, Norbert Dillier, Flurin Pfiffner, Adrian Dalbert
Summary: This study investigates the relationship between cochlear implant electrode positioning and electrical impedance measurements. The results show that three-point and four-point impedances are strongly correlated with electrode-modiolar distance, while monopolar impedances are minimally affected by changes in electrode positioning. The findings have significant implications for predicting electrode positioning during cochlear implant insertion in real-time using electrical impedance measurements.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2022)
Article
Audiology & Speech-Language Pathology
Meisam K. Arjmandi, Kelly N. Jahn, Julie G. Arenberg
Summary: This study examined the relationship between electrode-neuron interface (ENI) quality and speech perception in pediatric and adult cochlear implant (CI) listeners. The results suggest that poor-quality ENIs may contribute to reduced speech outcomes in both children and adults.
Article
Neurosciences
Aniket A. Saoji, Madison K. Graham, Weston J. Adkins, Kanthaiah Koka, Matthew L. Carlson, Brian A. Neff, Colin L. W. Driscoll, Douglas C. Fitzpatrick
Summary: Multi-frequency electrocochleography and electrode scan can be used to differentiate between different mechanisms for decreasing cochlear microphonics amplitude during cochlear implant electrode placement.
Article
Radiology, Nuclear Medicine & Medical Imaging
Behnam Molaee-Ardekani, Mary J. Donahue
Summary: This study uses the Cole model and the Basic RC model to fit the stimulation pulse voltage response (SPVR) and electrochemical impedance spectroscopy (EIS) data, and finds that different methods may result in different model fits in the literature. Furthermore, the EIS method provides a more accurate estimation of mid-to-low frequency characteristics, but its results should not be extrapolated to unobserved frequencies.
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2023)
Review
Materials Science, Multidisciplinary
Xiaomin Han, Ying Bai, Ran Zhao, Yu Li, Feng Wu, Chuan Wu
Summary: This review provides a comprehensive overview of the development and properties of electrolytes in rechargeable aluminum batteries (RABs). Various types of electrolytes, including ionic liquids, high temperature salts, organic electrolytes, aqueous electrolytes, and polymer electrolytes, are discussed. The focus is on the properties and compositions of ionic liquid electrolytes, which are the most commonly used electrolytes in RABs, as well as the electrode/electrolyte interfaces in different electrolyte environments. This review aims to guide the selection of appropriate electrolytes and clarify the energy storage mechanism of RABs.
PROGRESS IN MATERIALS SCIENCE
(2022)
Article
Audiology & Speech-Language Pathology
Yu Dong, Jeroen J. Briaire, Michael Siebrecht, H. Christiaan Stronks, Johan H. M. Frijns
Summary: The study aimed to detect electrode array translocations in cochlear implant patients by measuring electrode impedance and access resistance using electrical field imaging. Results showed that access resistance had significantly better accuracy in detecting translocations compared to electrode impedance. Access resistance also reliably detected the location of translocations, while electrode impedance did not show significant correlation. Measuring access resistance is recommended for detecting electrode translocations and improving surgical skills to reduce misplacements.
Article
Medicine, General & Internal
Angel Ramos de Miguel, Diego Riol Sancho, Juan Carlos Falcon-Gonzalez, Joana Pavone, Leandro Rodriguez Herrera, Silvia Borkoski Barreiro, Nadia Falcon Benitez, Angel Ramos Macias
Summary: This experimental research evaluated the use of the trans-impedance matrix (TIM) as a method of monitoring cochlear insertion for a precurved slim modiolar electrode array. The results showed that the TIM patterns correlated with the electrode position and could be an effective method for electrode positioning.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Milan Urik, Sona Sikolova, Dagmar Hosnova, Vit Kruntorad, Michal Bartos, Petr Jabandziev
Summary: This study found significant relationships between daily device use and functional gain, wearing comfort, and long-term safety.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Chemistry, Analytical
Soowon Shin, Yoonhee Ha, Gwangjin Choi, Junewoo Hyun, Sangwoo Kim, Seung-Ha Oh, Kyou-Sik Min
Summary: A manufacturable 32-channel cochlear electrode array is introduced in this study, which is manufactured by semi-automated laser micro-structuring and a mass-produced layer-by-layer silicone deposition scheme. The feasibility of the electrode array is assessed through electrochemical evaluation, stiffness measurements, and insertion force measurements, showing promising results for further development.
Article
Engineering, Biomedical
Gwangjin Choi, Yoonhee Ha, Doo-Hee Kim, Soowon Shin, Junewoo Hyun, Sangwoo Kim, Seung-Ha Oh, Kyou-Sik Min
Summary: This paper reports the reliability evaluation results of a manufacturable 32-channel cochlear electrode array. The electrode array manufacturing methods were developed using automated laser micro-machining process and silicone deposition scheme. The reliability of the electrode array was verified through ISO standards and human temporal bone studies.
BIOMEDICAL MICRODEVICES
(2023)
Article
Health Care Sciences & Services
Francesco Prata, Gianluigi Raso, Alberto Ragusa, Andrea Iannuzzi, Francesco Tedesco, Loris Cacciatore, Angelo Civitella, Piergiorgio Tuzzolo, Giuseppe D'Addurno, Pasquale Calle, Salvatore Basile, Marco Fantozzi, Matteo Pira, Salvatore Mario Prata, Umberto Anceschi, Giuseppe Simone, Roberto Mario Scarpa, Rocco Papalia
Summary: In this study, we performed off-clamp robot-assisted partial nephrectomy (RAPN) using the HugoTM RAS System. A simplified three-arm configuration was used for trocar placement and docking, resulting in feasible and safe practice with non-inferior perioperative outcomes.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Clinical Neurology
Kelly N. Jahn, Charlotte Morse-Fortier, Amanda M. Griffin, David Faller, Michael S. Cohen, Margaret A. Kenna, Elizabeth Doney, Julie G. Arenberg
Summary: The relationship between etiology of hearing loss, cochlear implant programming levels, and speech perception performance was investigated in a large clinical cohort of pediatric cochlear implant recipients. The study found that children with enlarged vestibular aqueduct had higher electrode impedances and programming levels compared to those with GJB2 mutation. However, speech perception scores were not influenced by etiology but were positively correlated with duration of cochlear implant experience.
OTOLOGY & NEUROTOLOGY
(2023)
Article
Clinical Neurology
Stephan Schraivogel, Philipp Aebischer, Stefan Weder, Marco Caversaccio, Wilhelm Wimmer
Summary: In this study, the association between residual hearing and estimated impedance subcomponents was evaluated. Results revealed a statistically significant negative effect of near-field impedance on residual hearing, suggesting that near-field impedance could be a more specific biomarker for monitoring residual hearing in cochlear implantation.
FRONTIERS IN NEUROLOGY
(2023)
Article
Polymer Science
Suheda Yilmaz-Bayraktar, Katharina Foremny, Michaela Kreienmeyer, Athanasia Warnecke, Theodor Doll
Summary: The gold standard for partial restoration of sensorineural hearing loss is cochlear implant surgery, but there are still limitations to music perception due to the gap between cochlear implant electrodes and auditory nerve cells. In this study, a bending or curling mechanism in the electrode array is discussed, and a silicone rubber-hydrogel actuator is proposed to reduce this gap and improve cochlear implant performance.
Article
Neurosciences
Joshua H. Goldwyn, John Rinzel
JOURNAL OF NEUROPHYSIOLOGY
(2016)
Editorial Material
Mathematical & Computational Biology
Mark D. McDonnell, Joshua H. Goldwyn, Benjamin Lindner
FRONTIERS IN COMPUTATIONAL NEUROSCIENCE
(2016)
Article
Neurosciences
Joshua H. Goldwyn, Myles McLaughlin, Eric Verschooten, Philip X. Joris, John Rinzel
JOURNAL OF NEUROSCIENCE
(2017)
Article
Biochemical Research Methods
Joshua H. Goldwyn, Bradley R. Slabe, Joseph B. Travers, David Terman
PLOS COMPUTATIONAL BIOLOGY
(2018)
Article
Mathematical & Computational Biology
Joshua H. Goldwyn, Eric Shea-Brown, Jay T. Rubinstein
JOURNAL OF COMPUTATIONAL NEUROSCIENCE
(2010)
Article
Neurosciences
Joshua H. Goldwyn, Jay T. Rubinstein, Eric Shea-Brown
JOURNAL OF NEUROPHYSIOLOGY
(2012)
Article
Neurosciences
Joshua H. Goldwyn, Myles Mc Laughlin, Eric Verschooten, Philip X. Joris, John Rinzel
JOURNAL OF NEUROSCIENCE
(2014)
Correction
Physics, Fluids & Plasmas
Joshua H. Goldwyn, Nikita S. Imennov, Michael Famulare, Eric Shea-Brown
Article
Physics, Fluids & Plasmas
Joshua H. Goldwyn, Nikita S. Imennov, Michael Famulare, Eric Shea-Brown
Review
Biochemical Research Methods
Joshua H. Goldwyn, Eric Shea-Brown
PLOS COMPUTATIONAL BIOLOGY
(2011)
Article
Biochemical Research Methods
Joshua H. Goldwyn, Michiel W. H. Remme, John Rinzel
PLOS COMPUTATIONAL BIOLOGY
(2019)
Article
Biology
Tom P. Franken, Brian J. Bondy, David B. Haimes, Joshua H. Goldwyn, Nace L. Golding, Philip H. Smith, Philip X. Joris
Summary: The study found that Lateral Superior Olive (LSO) neurons exhibit exquisite sensitivity to interaural time differences (ITDs) and can accurately process transient sound information. Inhibition in LSO neurons can block excitation over an extremely short window, achieved through inhibitory synapses on the axon initial segment.
Article
Gerontology
RW Johnson, CE Uccello, JH Goldwyn