Article
Multidisciplinary Sciences
Fatima Nari, Juwon Park, Nayeon Kim, Dong Jin Kim, Jae Kwan Jun, Kui Son Choi, Mina Suh
Summary: This study examined the impact of deprivation on breast cancer screening participation rates among South Korean women. The results showed that the participation rates increased gradually across all age groups from 2005 to 2018, and women in their 60s consistently had high participation rates. Regions with higher levels of deprivation also had higher participation rates in 2005 and 2012, but not in 2018. This suggests an association between deprivation and breast cancer screening participation rates.
SCIENTIFIC REPORTS
(2023)
Article
Oncology
Ke-Xun Yu, Wei-Jie Yuan, Chang-Hao Huang, Lei Xiao, Run-Sha Xiao, Peng-Wei Zeng, Lu Chen, Zi-Hua Chen
Summary: This study examines the association between socioeconomic deprivation and survival outcomes among colorectal cancer (CRC) patients. The findings suggest that CRC patients from socioeconomically disadvantaged areas have worse survival outcomes, and this association is influenced by various factors such as age, race, insurance status, disease stage, and treatment received.
AMERICAN JOURNAL OF CANCER RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Krishna P. Sharma, Amy DeGroff, Annette E. Maxwell, Allison M. Cole, Ngoc Cam Escoffery, Peggy A. Hannon
Summary: Client reminders, provider assessment and feedback, and colorectal cancer screening champions were found to be associated with increased clinic-level colorectal cancer screening rates according to this study. The universal implementation of these strategies can substantially increase colorectal cancer screening rates in the U.S.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2021)
Article
Oncology
Desiree Schliemann, Kogila Ramanathan, Nicholas Matovu, Ciaran O'Neill, Frank Kee, Tin Tin Su, Michael Donnelly
Summary: Implementation of CRC screening programmes in low- and middle-income countries faces various opportunities and challenges, including reporting of CRC cases and screening, cost-effective screening methods, knowledge about CRC and screening, staff resources and training, infrastructure of the health care system, financial resources, public health campaigns, policy commitment from governments, patient navigation, planning of screening programmes and quality assurance.
Article
Surgery
Joshua Herb, Lisette Dunham, Karyn Stitzenberg
Summary: This study aims to compare the performance of different measures of area socioeconomic status (SES) in predicting guideline concordant care and overall survival, and found that several measures were significantly associated with guideline concordant care and overall survival.
JOURNAL OF SURGICAL RESEARCH
(2022)
Review
Public, Environmental & Occupational Health
Kelsey M. Leach, Marni E. Granzow, Madyson L. Popalis, Kelsey C. Stoltzfus, Jennifer L. Moss
Summary: A scoping review of existing US-based interventions to improve CRC screening was conducted, revealing a positive impact on screening effectiveness. Projects with more components, patient navigation, and free/low-cost testing had greater effects on screening rates. Therefore, organizations implementing CRC screening programs should consider both intervention components and relevant program materials.
PREVENTIVE MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Charlotte Sturley, Paul Norman, Michelle Morris, Amy Downing
Summary: This study found an association between socio-economic status (SES) and colorectal cancer (CRC) incidence and survival, both at the individual and area levels. Individual-level factors such as educational attainment, social class, and housing tenure, as well as area-level deprivation, were found to be related to CRC incidence and survival. These findings highlight the importance of considering SES in public health interventions for CRC.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Multidisciplinary Sciences
Mercedes Vanaclocha-Espi, Marina Pinto-Carbo, Javier Martin-Pozuelo, Paula Romeo-Cervera, Rosana Peiro-Perez, Carmen Barona, Francisco Ortiz, Andreu Nolasco, Susana Castan, Dolores Salas, Ana Molina-Barcelo
Summary: An individual socioeconomic status index (ISESI) was constructed and validated using data from the Population Information System of the Region of Valencia, Spain. The index was used to analyze inequalities in a colorectal cancer screening program. The study found that socioeconomic status was an important factor influencing participation in the screening program.
Article
Surgery
Benjamin D. Powers, William Fulp, Amina Dhahri, Danielle K. DePeralta, Takuya Ogami, Luke Rothermel, Jennifer B. Permuth, Susan T. Vadaparampil, Joon-Kyung Kim, Jose Pimiento, Pamela J. Hodul, Mokenge P. Malafa, Daniel A. Anaya, Jason B. Fleming
Summary: This study found that socioeconomic status did not significantly impact the treatment quality and survival of pancreatic cancer patients at a high-volume cancer center with a standardized clinical pathway.
Article
Medicine, General & Internal
Birgitte Skau, Ulrik Deding, Lasse Kaalby, Gunnar Baatrup, Morten Kobaek-Larsen, Issam Al-Najami
Summary: This study investigates the association between socioeconomic status and the risk of incomplete colonoscopy in the Danish Colorectal Cancer Screening Program. The results suggest that low income and high school/vocational education are associated with an increased risk of incomplete colonoscopy.
Article
Oncology
Edoardo Botteri, Geir Hoff, Kristin R. Randel, Oyvind Holme, Thomas de Lange, Tomm Bernklev, Eline Aas, Mona Berthelsen, Erik Natvig, Benedicte Kirkoen, Markus D. Knudsen, Ane S. Kvaerner, Anna L. Schult, Giske Ursin, Anita Jorgensen, Paula Berstad
Summary: This study assessed the participation rates of different population subgroups in colorectal cancer screening, and found that male gender, young age, low education and income, being retired or unemployed, living alone, being an immigrant, long driving time, and the use of certain drugs were associated with low participation. It was also found that fecal immunochemical testing (FIT) screening had more equal access compared to sigmoidoscopy screening.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Medicine, General & Internal
Cici Bauer, Kehe Zhang, Qian Xiao, Jiachen Lu, Young-Rock Hong, Ryan Suk
Summary: This study examined the geographic variation of cancer screening rates in US counties and the association between county-level social vulnerability index (SVI) and screening rates. The findings showed that higher SVI was associated with lower odds of cancer screening. The study highlights regional disparities in cancer screening rates and provides insights for future interventions targeting cancer prevention disparities.
Article
Oncology
Ahmed Bedir, Semaw Ferede Abera, Dirk Vordermark, Daniel Medenwald
Summary: This study aimed to measure the impact of socioeconomic inequality on endometrial cancer survival. The results showed that the overall survival rate decreased as the level of deprivation increased. Stage I patients living in the most deprived districts had a higher risk of overall mortality.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2022)
Article
Oncology
Isabelle Finke, Gundula Behrens, Werner Maier, Lars Schwettmann, Ron Pritzkuleit, Bernd Holleczek, Hiltraud Kajueter, Michael Gerken, Johann Mattutat, Katharina Emrich, Lina Jansen, Hermann Brenner
Summary: The study investigated the association between area-based socioeconomic deprivation on municipality level and cancer survival for 25 cancer sites in Germany. Despite adjusting for stage, most cancer patients showed significant socioeconomic inequalities in survival rates. Trend analyses indicated improved survival over recent periods, but persisting deprivation differences in cancer survival still existed.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Multidisciplinary Sciences
Sonja Tomsic, Tina Zagar, Ana Mihor, Miran Mlakar, Katarina Lokar, Katja Jarm, Vesna Zadnik
Summary: This study demonstrates the impact of organized breast cancer screening on diagnosis and treatment, showing a reduction in disease stage and improved survival.
Article
Behavioral Sciences
Sandro T. Stoffel, Mariella Bombagi, Robert S. Kerrison, Christian von Wagner, Benedikt Herrmann
Summary: The study tested an alternative screening strategy called enhanced active choice, which was found to increase screening participation among men. However, there were no statistically significant differences in overall acceptance and participation rates between the two conditions.
BEHAVIORAL MEDICINE
(2022)
Article
Oncology
Siu Hing Lo, Rohini Sharma, Charlotte E. Costentin, Daniel Aggio, Suki Shergill, Fabien Colaone, Victoria K. Brennan, Vincenzo A. Straccia, Ion Agirrezabal, Andrew J. Lloyd
Summary: The study revealed that patients with advanced hepatocellular carcinoma (HCC) prioritize overall survival (OS) followed by reducing risks of diarrhea and hypertension, and other adverse events (AEs). They were willing to trade off OS to minimize AE risks in order to maintain their quality of life.
Article
Economics
Siu Hing Lo, Jade Marshall, Hanna Skrobanski, Andrew Lloyd
Summary: This study estimated health state utilities to understand the impact of seizure type and frequency on quality of life for patients with tuberous sclerosis complex and their caregivers. Findings highlighted the significant burden of living with TSC and caring for a child with TSC, with greater burden associated with generalized seizures and worsened by increasing seizure frequency.
PHARMACOECONOMICS-OPEN
(2022)
Article
Economics
Siu Hing Lo, Andrew Lloyd, Shuayb Elkhalifa, Zlatko Sisic, Floortje E. van Nooten
Summary: TTO utility values show that HAE imposes a significant burden on patients and caregivers, with the burden influenced by attack location. These findings were consistent with the ratings from members of the general public.
PHARMACOECONOMICS-OPEN
(2022)
Article
Substance Abuse
Alexander Adamson, Laura Portas, Simone Accordini, Alessandro Marcon, Deborah Jarvis, Gianluca Baio, Cosetta Minelli
Summary: Incorporating personalised disease risk communication into general practitioners' practices to motivate smoking cessation in England is likely to be cost-effective compared with usual care, according to evidence to date.
Article
Economics
Siu Hing Lo, Ksenija Gorni, C. Simone Sutherland, Yasmina Marti, Andrew Lloyd, Noman Paracha
Summary: The study found that patients and caregivers prioritize improved motor and breathing function, preferring oral treatment. Disutilities were substantial for SMA disease outcomes and care aspects, illustrating the importance of motor and breathing function in treatment decisions.
Article
Economics
Siu Hing Lo, Claire Lawrence, Yasmina Marti, Andreia Cafe, Andrew J. Lloyd
Summary: The study results indicate that patients and caregivers prioritize improvement or stabilization of motor and breathing function, prefer oral treatments and treatments with demonstrated effectiveness in Types 2-3 SMA, and tend to avoid the risk of liver injury.
Article
Oncology
Juliet Usher-Smith, Christian von Wagner, Alex Ghanouni
Summary: Cancer screening programmes play a significant role in reducing cancer incidence and mortality. Personalised risk estimates can improve effectiveness and cost-effectiveness, as well as reduce harms of screening programmes. Risk-adapted colorectal cancer screening raises important questions that require further research and testing. Conducting behavioural science research alongside clinical research will help ensure that risk-adapted screening is understood and accepted by the population it aims to serve.
Article
Public, Environmental & Occupational Health
Sandro T. Stoffel, Lesley McGregor, Yasemin Hirst, Sahida Hanif, Lorraine Morris, Christian von Wagner
Summary: This study evaluated the effectiveness of the 'Call for a Kit' health promotion intervention in improving bowel cancer screening uptake. The results showed that both in-person consultations and phone consultations were effective in encouraging individuals to return test kits. Sociodemographic characteristics such as gender and socioeconomic status were found to impact the test kit return rate.
JOURNAL OF MEDICAL SCREENING
(2022)
Article
Public, Environmental & Occupational Health
Robert Stephen Kerrison, Andrew Prentice, Sarah Marshall, Christian von Wagner
Summary: Despite efforts to increase participation in colorectal cancer screening in England, most cases are diagnosed outside of the screening program. This study found that the main reason for this is suboptimal uptake of screening, with nearly two-thirds of eligible patients never participating. It highlights the need to encourage greater participation in order to improve outcomes.
JOURNAL OF MEDICAL SCREENING
(2022)
Article
Social Sciences, Mathematical Methods
Mariam O. Adeleke, Gianluca Baio, Aidan G. O'Keeffe
Summary: This paper explores the use of regression discontinuity designs (RDDs) for time-to-event outcomes subject to right censoring. An accelerated failure time (AFT) approach is used to estimate the treatment effect of a fuzzy RDD, which can account for different levels of fuzziness and unobserved confounding. Simulation studies show that this estimation approach performs well compared to established structural AFT models.
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY
(2022)
Article
Health Care Sciences & Services
Aradhna Kaushal, Caroline Bravo, Stephen Duffy, Douglas Lewins, Ralph Moehler, Rosalind Raine, Ivo Vlaev, Jo Waller, Christian von Wagner
Summary: The aim of this project is to develop, publish, and promote a list of items for the Reporting Guidelines for Social Media Research (RESOME) checklist. RESOME will be developed using a modified Delphi approach, and experts and stakeholders will be invited to participate in two rounds of questionnaires to reach a consensus. The guidelines will be published in a paper, and before publication, they will be piloted and refined to ensure clarity and understanding.
JMIR RESEARCH PROTOCOLS
(2022)
Article
Respiratory System
Andrea Gabrio, Necdet B. Gunsoy, Gianluca Baio, Alan Martin, Victoria F. Paly, Nancy Risebrough, David M. G. Halpin, Dave Singh, Robert A. Wise, MeiLan K. Han, Fernando J. Martinez, Gerard J. Criner, Neil Martin, David A. Lipson, Afisi S. Ismaila
Summary: Triple therapy with fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) showed better clinical benefits compared to dual therapy in the treatment of COPD, and also resulted in lower healthcare resource utilization costs related to COPD.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2022)
Article
Medicine, General & Internal
Sandro T. Stoffel, Aradhna Kaushal, Aikaterini Grimani, Christian von Wagner, Falko F. Sniehotta, Ivo Vlaev
Summary: This study examined whether communicating the social benefit through community protection for friends and family members versus overall society affects vaccination intention and perception. The findings suggest that although highlighting the social benefits of COVID-19 vaccinations can increase intentions among vaccine non-intenders, they are unlikely to address barriers among ethnically diverse communities.
Review
Medicine, General & Internal
Ghalia Kayal, Robert Kerrison, Yasemin Hirst, Christian von Wagner
Summary: Colonoscopy is a commonly used screening and diagnostic test for colorectal cancer (CRC). This review examined patient experiences with colonoscopy following a positive screening result, and identified areas for improvement in patient experience, including making bowel preparation more acceptable, reducing pain and discomfort during the test, and alleviating post-colonoscopy symptoms.