Review
Behavioral Sciences
Mackenzie Rubens, Dagmar Bruenig, Jessica A. M. Adams, Shruthi M. Suresh, Anita Sathyanarayanan, Divna Haslam, Chad E. Shenk, Ben Mathews, Divya Mehta
Summary: This systematic review of literature examines the DNA methylation associated with child maltreatment in non-clinical populations. The review summarizes the methods used in research, how different types of maltreatment and age of exposure are encoded through methylation, and the genes consistently associated with child maltreatment. The findings suggest the need for future studies to use conceptually robust definitions of maltreatment and incorporate important contextual information such as age of exposure and subtype of maltreatment.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Clinical Neurology
Anthony N. Reffi, David A. Kalmbach, Philip Cheng, Tanja Jovanovic, Seth D. Norrholm, Minden B. Sexton, Gregory Mahr, Lily Arnett, Grace Seymour, Christopher L. Drake
Summary: The association between childhood abuse experiences and adult insomnia appears to be mediated through sleep reactivity. Emotional and physical abuse histories in childhood are associated with more severe insomnia symptoms, while sexual abuse history does not have a direct association. These findings hold true regardless of gender, age, and stress related to COVID-19.
Article
Psychology, Clinical
Cheryl R. Stein, Margaret A. Sheridan, William E. Copeland, Laura S. Machlin, Kimberly L. H. Carpenter, Helen L. Egger
Summary: The association between adversity and psychopathology in preschool-aged children differs depending on the type of adversity, with threat being strongly related to behavioral disorders and cumulative risk being consistently related to all psychopathologies.
DEPRESSION AND ANXIETY
(2022)
Review
Family Studies
Sinead D'arcy-Bewick, Antonio Terracciano, Nicholas Turiano, Angelina R. Sutin, Roisin Long, Paraic S. O'Suilleabhain
Summary: Research findings suggest an association between childhood abuse and neglect (CAN) and adult mortality risk. However, the relationship varies based on the type of abuse and neglect as well as gender. The literature has limitations, and further research is needed to address these limitations.
CHILD ABUSE & NEGLECT
(2022)
Article
Clinical Neurology
Yuanyuan Xiao, Linling Jiang, Runxu Yang, Hailiang Ran, Tianlan Wang, Xingting He, Xiufeng Xu, Jin Lu
Summary: This study found a significant association between childhood maltreatment experience and school bullying behaviors, especially in relation to sexual abuse and emotional abuse with an increased risk of bullying victimization among Chinese adolescents. Therefore, targeted intervention measures should be implemented to protect abused adolescents from bullying at school.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Clinical
Camille Souama, Yuri Milaneschi, Femke Lamers, Christiaan H. Vinkers, Erik J. Giltay, Edith J. Liemburg, Brenda W. J. H. Penninx
Summary: Childhood trauma is associated with the development of metabolic syndrome over time. This association is related to the biological risk factors for cardiometabolic disease and is unaffected by lifestyle.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Theresa K. Haidl, Dennis M. Hedderich, Marlene Rosen, Nathalie Kaiser, Mauro Seves, Thorsten Lichtenstein, Nora Penzel, Julian Wenzel, Lana Kambeitz-Ilankovic, Anne Ruef, David Popovic, Frauke Schultze-Lutter, Katharine Chisholm, Rachel Upthegrove, Raimo K. R. Salokangas, Christos Pantelis, Eva Meisenzahl, Stephen J. Wood, Paolo Brambilla, Stefan Borgwardt, Stephan Ruhrmann, Joseph Kambeitz, Nikolaos Koutsouleris
Summary: The study found that childhood trauma is a transdiagnostic risk factor for mental health disorders, possibly related to depressive symptoms. However, it is not possible to differentiate between different diagnosis-dependent psychopathologies, suggesting a multi-factorial pathogenesis.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Family Studies
Sophie A. Rameckers, Arnold A. P. van Emmerik, Nathan Bachrach, Christopher W. Lee, Nexhmedin Morina, Arnoud Arntz
Summary: The study found that emotional abuse was the only type of trauma significantly related to the severity of PTSD and specific symptom clusters, emphasizing the important role of emotional abuse in Ch-PTSD and the need for treatment to address childhood emotional abuse.
CHILD ABUSE & NEGLECT
(2021)
Article
Immunology
Antonella Trotta, Louise Arseneault, Andrea Danese, Valeria Mondelli, Line J. H. Rasmussen, Helen L. Fisher
Summary: The study found that young people reporting psychotic experiences and childhood victimization were more likely to have elevated levels of suPAR, CRP, and IL-6 at age 18. However, this association was weakened when adjusting for other risk factors for elevated inflammation. In contrast, individuals reporting psychotic experiences without childhood victimization or childhood victimization without psychotic experiences did not show significant associations with inflammatory markers at age 18.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Clinical Neurology
Alan R. King
Summary: Childhood adversity in various forms is associated with higher prevalence rates of different mood and anxiety disorders. Sexual, emotional, and physical abuse are linked to increased risk of these disorders. Interactive effects between adversities are limited, with significant impact from unitary adversities.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Public, Environmental & Occupational Health
Siyu Zhu, Shiyi Shan, Wen Liu, Shuting Li, Leying Hou, Xuanyin Huang, Yi Liu, Qian Yi, Weidi Sun, Kun Tang, Davies Adeloye, Igor Rudan, Peige Song
Summary: The study found that there is a certain association between adverse childhood experiences and adult diabetes, especially for those who have experienced economic adversity, physical abuse, sexual abuse, verbal abuse, and incarceration.
JOURNAL OF GLOBAL HEALTH
(2022)
Article
Psychiatry
Jiajing Chen, Dong Mei Wang, Fusheng Fan, Fabing Fu, Dejun Wei, Shanshan Tang, Yang Tian, Yuxuan Du, Rongrong Zhu, Yuqing Li, Li Wang, Xiang-Yang Zhang
Summary: This study found that maltreated methamphetamine-dependent individuals (METH-DIs) have cognitive deficits, which are associated with their experience of childhood maltreatment. These maltreated patients are also more likely to have lower education levels, higher levels of depression, and an earlier onset age of drug use.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Review
Psychiatry
Victor De la Pena-Arteaga, Sarah O. Nogueira, Michael Lynskey, Lindsey A. Hines
Summary: This systematic review explores the relationship between childhood maltreatment, specifically physical and sexual abuse, and adolescent cannabis use. The results suggest that childhood maltreatment may increase the risk of adolescent cannabis use. While some studies considered variations in the timing of cannabis initiation and gender differences, further exploration of the role of adolescent cannabis use in the causal pathway between childhood abuse and adult mental health problems is needed.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Clinical Neurology
Ishaq Abu-Arafeh, Amy A. Gelfand
Summary: This article discusses the different phenotypes of migraine in children and advocates for the integration of abdominal migraine, cyclical vomiting syndrome, and other related conditions into the unified diagnosis of 'childhood migraine syndrome'. Such integration can guide clinicians to consider migraine in the assessment of children with these disorders and stimulate research into the genetics, pathophysiology, and clinical features of all disorders within the syndrome.
NATURE REVIEWS NEUROLOGY
(2021)
Article
Psychiatry
Mariesa Cay, Virginie-Anne Chouinard, Mei-Hua Hall, Ann K. Shinn
Summary: This study aimed to examine the reliability of self-reports of childhood trauma in psychotic disorders. The study found that patients with schizophrenia and psychotic bipolar disorder can provide reliable self-reports, especially related to physical and emotional abuse.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
