Journal
HAUTARZT
Volume 61, Issue 12, Pages 1052-1055Publisher
SPRINGER
DOI: 10.1007/s00105-010-1998-4
Keywords
Epidermodysplasia verruciformis; Imiquimod; Human papillomavirus; UV exposition; Carcinoma
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A 19-year-old patient presented with epidermodysplasia verruciformis (EV). In this genodermatosis, pathogenetic factors such as infection by human papilloma viruses as well as sun exposure are considered responsible for the malignant transformation of EV lesions to skin cancer within decades. So far, several therapeutic strategies have been unsatisfactory. In our case HPV 5b was detected and the associated skin lesions were successfully treated with imiquimod 5% cream.
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