Article
Food Science & Technology
Huihui Shen, Xiuxian Song, Yue Zhang, Peipei Zhang, Jing Li, Weijia Song, Zhiming Yu
Summary: This study investigated the BTX metabolites of a Chinese strain of Karenia brevis 165, revealing significant differences in metabolite types and concentrations at different growth stages, which can help assess ecological disaster risks.
Article
Marine & Freshwater Biology
Elizabeth Brammer-Robbins, Kaylie Anne Costa, John A. Bowden, Christopher J. Martyniuk, Iske V. Larkin, Nancy D. Denslow
Summary: Red tide events caused by Karenia brevis pose health risks to humans and wildlife. Brevetoxins produced by K. brevis can modulate immune responses and have various effects on marine species. Further research is needed to fully understand the immunotoxicity of brevetoxins and their long-term impacts on organismal health.
AQUATIC TOXICOLOGY
(2022)
Article
Toxicology
Jeremy Lund, Emily Wheeler, Tamas Peredy
Summary: A group of tourists developed neurotoxic shellfish poisoning symptoms after consuming contaminated clams during a red tide event. Following presentation to the emergency department, all patients received supportive care only, and symptoms resolved within 24 hours.
CLINICAL TOXICOLOGY
(2023)
Article
Ecology
Daria L. Clark, Jan A. Pechenik
Summary: This study highlights the impact of harmful algae on the early developmental stages of Atlantic slipper limpets. Larvae exposed to high concentrations of harmful algae exhibited slower shell growth rates, delayed competence for metamorphosis, and reduced post-metamorphic growth.
MARINE ECOLOGY PROGRESS SERIES
(2022)
Article
Marine & Freshwater Biology
Victoria M. Devillier, Emily R. Hall, Donald M. Anderson, Kristy A. Lewis
Summary: Harmful algal blooms, specifically the toxic marine dinoflagellate Karenia brevis, are a threat to both human health and marine ecosystems. This study evaluated the effects of a modified clay (PAC-MC) on blue crabs exposed to K. brevis. The results showed that the clay treatment had no significant impact on crab mortality and reflex variables. This suggests that PAC-MC may be a viable option for treating K. brevis blooms without harming adult blue crab populations.
Article
Marine & Freshwater Biology
Ricardo Colon, Kathleen S. Rein
Summary: The research reveals significant differences in toxin production between different cultures of Karenia brevis, with implications on energy-dependent quenching and reduced thiol content in the proteome. High and low toxin-producing cultures show physiological variations in gene and protein expression related to the xanthophyll cycle, as well as differences in lipid composition affecting the cycle.
Article
Marine & Freshwater Biology
A. Skripnikov, N. Wagner, J. Shafer, M. Beck, E. Sherwood, M. Burke
Summary: This research evaluated the accuracy of red tide topic activity on Twitter and found strong correlations between tweet activity and actual red tide conditions. The results indicate that Twitter can provide a trustworthy reflection of the local impacts and development of red tide over time, potentially enhancing assessment and response to disasters.
Article
Marine & Freshwater Biology
Charles L. Tilney, Katherine A. Hubbard
Summary: Study evaluated the photobiology and molecular mechanisms of high-light tolerance in K. brevis, showing increased PSII photoinactivation, repair, NPQ, and F-v/F-m under high-light conditions. Phylogeny of ftsH-like genes revealed acquisition during tertiary endosymbiosis, with high-light cultures showing upregulation of thylakoid-associated genes, supporting K. brevis success in the Gulf of Mexico.
Article
Environmental Sciences
Philip M. Gravinese, Kaili M. Gregory, Jessica H. Bartzick, Emily R. Ramos, Samantha M. Stewart, Vincent J. Lovko
Summary: Moderate concentrations of red tide can have sublethal effects on stone crabs, reducing larval survival. Mitigation measures to decrease bloom concentrations may help alleviate pressure on stone crab populations.
MARINE ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Spencer E. Fire, Glenn A. Miller, Edna R. Sabater, Randall S. Wells
Summary: Exposure of common bottlenose dolphins to brevetoxins produced by toxic phytoplankton Karenia brevis can result in severe health impacts, yet the relationship between K. brevis bloom severity and corresponding PbTx concentrations in live dolphins remains unclear. Our study analyzed PbTx concentrations in various samples from 253 live dolphins sampled in Sarasota Bay, Florida, finding a significant association between PbTx-positive animals and elevated K. brevis abundances. However, we did not find a statistically significant relationship between K. brevis cell abundance and PbTx concentration in different sample types.
FRONTIERS IN MARINE SCIENCE
(2021)
Article
Engineering, Marine
Marvin F. Li, Patricia M. Glibert, Vyacheslav Lyubchich
Summary: The frequency, magnitude, and impact of harmful algal blooms (HABs) have increased globally. Machine learning algorithms, such as RVM and NB, show better abilities in predicting blooms. The importance of upwelling-favorable winds, onshore winds, and river flows in regulating blooms has been quantified.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Brendan P. Norman, Andrew S. Davison, Juliette H. Hughes, Hazel Sutherland, Peter JM. Wilson, Neil G. Berry, Andrew T. Hughes, Anna M. Milan, Jonathan C. Jarvis, Norman B. Roberts, Lakshminarayan R. Ranganath, George Bou-Gharios, James A. Gallagher
Summary: This study conducted a metabolomic analysis of AKU disease and identified the metabolic effects of HGD deletion. The findings provide insights into the overall tyrosine metabolism and discovered previously unknown pathways. This research contributes to a better understanding and potential treatment options for AKU disease.
Article
Marine & Freshwater Biology
So Hyun Ahn, Patricia M. Glibert, Cynthia A. Heil
Summary: During 2020-2021, there was an unusually prolonged bloom of toxigenic dinoflagellate Karenia brevis along the Gulf coast of Florida, causing severe environmental effects. The study found that the summer populations were photosynthetically and nutritionally stressed, but showed a stronger response to urea than other nitrogen substrates.
Review
Engineering, Environmental
Xin Wang, Qingqing Zhu, Chunyang Liao, Guibin Jiang
Summary: Organophosphate flame retardants (OPFRs), especially organophosphate esters (OPEs), have raised concerns on environmental and health risks. Biomonitoring research provides precise information on human exposure, while knowledge on biotransformation and metabolism of OPEs is crucial for understanding internal exposure. Further developments in methodologies for urine sampling and estimation on internal exposure to OPEs are needed.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Marine & Freshwater Biology
Chuanmin Hu, Yao Yao, Jennifer P. Cannizzaro, Matt Garrett, Mary Harper, Laura Markley, Celia Villac, Katherine Hubbard
Summary: This study addresses the lack of comprehensive assessments on the spatial extent and temporal occurrence of harmful algal blooms caused by Karenia brevis. It proposes an approach to combine microscopy evaluation and satellite remote sensing to estimate bloom occurrence frequency, intensity, and extent. The derived bloom statistics provide valuable insights and complement traditional microscopy taxonomy data.
Article
Marine & Freshwater Biology
Remington X. Poulin, Kelsey L. Poulson-Ellestad, Jessie S. Roy, Julia Kubanek
Review
Biochemistry & Molecular Biology
Bhuwan Khatri Chhetri, Serge Lavoie, Anne Marie Sweeney-Jones, Julia Kubanek
NATURAL PRODUCT REPORTS
(2018)
Article
Multidisciplinary Sciences
Remington X. Poulin, Serge Lavoie, Katherine Siegel, David A. Gaul, Marc J. Weissburg, Julia Kubanek
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2018)
Article
Chemistry, Organic
Serge Lavoie, Anne Marie Sweeney-Jones, Nazia Mojib, Brandon Dale, Kerstin Gagaring, Case W. McNamara, Cassandra L. Quave, Katy Soapi, Julia Kubanek
JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Organic
Bhuwan Khatri Chhetri, Serge Lavoie, Anne Marie Sweeney-Jones, Nazia Mojib, Vijay Raghavan, Kerstin Gagaring, Brandon Dale, Case W. McNamara, Katy Soapi, Cassandra L. Quave, Prasad L. Polavarapu, Julia Kubanek
JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Limnology
Nazia Mojib, Julia Kubanek
LIMNOLOGY AND OCEANOGRAPHY
(2020)
Article
Limnology
Emily R. Brown, Julia Kubanek
LIMNOLOGY AND OCEANOGRAPHY
(2020)
Article
Multidisciplinary Sciences
Nastassia Patin, Emily Brown, Gabriella Chebli, Claire Garfield, Julia Kubanek, Frank J. Stewart
Article
Biochemistry & Molecular Biology
Samantha J. Mascuch, Sara Fakhretaha-Aval, Jessica C. Bowman, Minh Thu H. Ma, Gwendell Thomas, Bettina Bommarius, Chieri Ito, Liangjun Zhao, Gary P. Newnam, Kavita R. Matange, Hem R. Thapa, Brett Barlow, Rebecca K. Donegan, Nguyet A. Nguyen, Emily G. Saccuzzo, Chiamaka T. Obianyor, Suneesh C. Karunakaran, Pamela Pollet, Brooke Rothschild-Mancinelli, Santi Mestre-Fos, Rebecca Guth-Metzler, Anton V. Bryksin, Anton S. Petrov, Mallory Hazell, Carolyn B. Ibberson, Petar I. Penev, Robert G. Mannino, Wilbur A. Lam, Andres J. Garcia, Julia Kubanek, Vinayak Agarwal, Nicholas V. Hud, Jennifer B. Glass, Loren Dean Williams, Raquel L. Lieberman
JOURNAL OF BIOLOGICAL CHEMISTRY
(2020)
Article
Multidisciplinary Sciences
Micah Dettweiler, Lewis Marquez, Michelle Lin, Anne M. Sweeney-Jones, Bhuwan Khatri Chhetri, Daniel V. Zurawski, Julia Kubanek, Cassandra L. Quave
SCIENTIFIC REPORTS
(2020)
Article
Marine & Freshwater Biology
Emily R. Brown, Sam G. Moore, David A. Gaul, Julia Kubanek
Summary: Traditionally, copepods have been thought to distinguish toxic from non-toxic prey by associating cell surface recognition with non-polar metabolites. LC/MS and NMR analysis revealed significant differences in the non-polar metabolomes of toxic Alexandrium species compared to their non-toxic counterparts, particularly in metabolites belonging to seven lipid classes.
Article
Plant Sciences
Bhuwan Khatri Chhetri, Philip R. Tedbury, Anne Marie Sweeney-Jones, Luke Mani, Katy Soapi, Candela Manfredi, Eric Sorscher, Stefan G. Sarafianos, Julia Kubanek
Summary: This article reports the antiviral activities of three marine natural products against SARS-CoV-2. These compounds can inhibit viral replication and may serve as promising candidates for novel drug leads.
JOURNAL OF NATURAL PRODUCTS
(2022)
Article
Limnology
Emily R. Brown, Sam G. Moore, David A. Gaul, Julia Kubanek
Summary: This study uncovers the subtle physiological responses of the phytoplankton Alexandrium minutum to copepodamides and suggests that copepodamides may disrupt enzyme activity, leading to increased toxin biosynthesis. This research provides important insights into the chemosensory ecology of predator-prey interactions in phytoplankton.
LIMNOLOGY AND OCEANOGRAPHY
(2022)
Article
Ecology
Samantha J. Mascuch, Alyssa Demko, Samson Viulu, Joape Ginigini, Katy Soapi, Paul Jensen, Julia Kubanek
Summary: Microbes produce natural products that can interact with each other and their environments, and these interactions can serve as a potential source of antibiotics. The biosynthesis of certain antibiotics can be induced by competing microbes. Competition among hosts can also affect the metabolic outputs of their microbiomes. This study discovered an interaction between two coral-associated bacteria, where one bacteria interfered with the antibiotic production of the other. This observation highlights the complex molecular dynamics among microbiome constituents.
Review
Biochemistry & Molecular Biology
Emily R. Brown, Marisa R. Cepeda, Samantha J. Mascuch, Kelsey L. Poulson-Ellestad, Julia Kubanek
NATURAL PRODUCT REPORTS
(2019)