A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)
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Title
A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)
Authors
Keywords
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Journal
HAEMOPHILIA
Volume 18, Issue 5, Pages 782-788
Publisher
Wiley
Online
2012-04-16
DOI
10.1111/j.1365-2516.2012.02780.x
References
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Note: Only part of the references are listed.- Bioequivalence between two serum-free recombinant factor VIII preparations (N8 and ADVATE®) - an open-label, sequential dosing pharmacokinetic study in patients with severe haemophilia A
- (2011) U. MARTINOWITZ et al. HAEMOPHILIA
- Pharmacokinetics and pharmacodynamics of a new recombinant FVIII (N8) in haemophilia A mice
- (2011) T. ELM et al. HAEMOPHILIA
- Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment
- (2010) B. Mei et al. BLOOD
- Functional characteristics of N8, a new recombinant FVIII
- (2010) M. L. S. CHRISTIANSEN et al. HAEMOPHILIA
- Towards a standardization of the murine tail bleeding model
- (2010) T. K. GREENE et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Optimization, refinement and reduction of murine in vivo experiments to assess therapeutic approaches for haemophilia A
- (2010) B Baumgartner et al. LABORATORY ANIMALS
- Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice
- (2009) J. Pan et al. BLOOD
- Pharmacokinetics and dose requirements of factor VIII over the age range 3–74 years
- (2009) Sven Björkman et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Purification and characterization of a new recombinant factor VIII (N8)
- (2009) L. THIM et al. HAEMOPHILIA
- A ferric chloride induced arterial injury model used as haemostatic effect model
- (2009) F. MØLLER et al. HAEMOPHILIA
- rFVIIa and a new enhanced rFVIIa-analogue, NN1731, reduce bleeding in clopidogrel-treated and in thrombocytopenic rats
- (2009) B. LAURITZEN et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Faster onset of effect and greater efficacy of NN1731 compared with rFVIIa, aPCC and FVIII in tail bleeding in hemophilic mice
- (2009) H. L. HOLMBERG et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Factor VIII requirement to maintain a target plasma level in the prophylactic treatment of severe hemophilia A: influences of variance in pharmacokinetics and treatment regimens
- (2009) P. W. COLLINS et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- The heparin-binding exosite of factor IXa is a critical regulator of plasma thrombin generation and venous thrombosis
- (2008) Y. Buyue et al. BLOOD
- Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots
- (2008) M. Neyman et al. BLOOD
- Prevention of haemarthrosis in a murine model of acute joint bleeding
- (2008) L. A. VALENTINO et al. HAEMOPHILIA
- Hemostatic effect of recombinant factor VIIa, NN1731 and recombinant factor VIII on needle-induced joint bleeding in hemophilia A mice
- (2008) K. ØVLISEN et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Break-through bleeding in relation to predicted factor VIII levels in patients receiving prophylactic treatment for severe hemophilia A
- (2008) P. W. COLLINS et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
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