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Association between cognitive impairment and motor dysfunction in patients with multiple sclerosis: A cross-sectional study

PUBLISHED June 19, 2023 (DOI: https://doi.org/10.54985/peeref.2306p9886438)



Hanadi Alharthi1 , Muneera Almurdi1
  1. King Saud University

Conference / event

The 6th International Conference on Disability and Rehabilitation, December 2022 (Riyadh, Saudi Arabia)

Poster summary

While most studies focus on cognitive impairment as a predictor of motor deficits in the neurological diseases, here we studied the association between CI and MD in patients with MS and examined if muscle weakness, incoordination, balance impairment, gait abnormalities, and/or increased fall risk are indicators of CI in patients with MS. In this study, cognitive impairment was assessed using the Montreal Cognitive Assessment Scale, muscle strength using a hand-held dynamometer, and balance, gait, and fall risk assessment using the Tinetti scale. Motor coordination was assessed using the timed rapid alternating movement test for the upper extremity and the timed alternate heel-to-knee test for the lower extremity. In summary, CI is significantly associated with motor incoordination, balance impairment, gait abnormality, and increased fall risk. The risk of fall and upper extremity incoordination appeared to be best indicators of CI in patients with MS.


Multiple sclerosis, Cognitive impairment, Motor dysfunction, Risk of fall

Research areas



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Supplemental files

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Additional information

Competing interests
No competing interests were disclosed.
Data availability statement
The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.
Creative Commons license
Copyright © 2023 Alharthi et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Alharthi, H., Almurdi, M. Association between cognitive impairment and motor dysfunction in patients with multiple sclerosis: A cross-sectional study [not peer reviewed]. Peeref 2023 (poster).
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