Improvements In Regional Left Ventricular Function After Late Percutaneous Coronary Intervention After Anterior Myocardial Infarction

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Authors

Srilakshmi Adhyapak¹ , Prahlad Menon²

1. St. John's Medical College
2. Pittsburgh University

Conference / event

Annual Research Day Conference 2021 of St. John's Research Institute, Bangalore, India, March 2021 (Virtual)

Poster summary

Late revascularization following a myocardial infarction has questionable clinical benefit. We studied 13 patients with anterior wall myocardial infarction who underwent percutaneous coronary intervention within 2 weeks of the primary event, by quantitative analysis of 2-dimensional echocardiographic images. Endocardial segmentations of the left ventricular (LV) endocardium from the 4-chamber views were studied over time to establish cumulative wall displacements (CWDs) throughout the cardiac cycle. Results: Left ventricular end-systolic volume decreased to 42 ± 8 mL/body surface area (P = .034) and LV ejection fraction improved to 52% ± 7% (P = .04). Analysis of LV endocardial CWD demonstrated significant improvements in mid-systolic to late-systolic phases in the apical LV segments, from 3.5 ± 0.32 to 5.89 ± 0.43 mm (P = .019). Following late establishment of infarct-related artery patency , regional improvements were noted in the LV apical segments during systole and late diastole.

Keywords

Left ventricle, Myocardial infarction, Coronary angioplasty

Research areas

Medicine, Medical Imaging

References

1. Steg G, James SK, Atar D, et al; Task Force Members. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012;33:2569–2619.
2. Wijns W, Kolh P, Danchin N, et al; Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS); European Association for Percutaneous Cardiovascular Interventions (EAPCI). Guidelines on myocardial revascularization. Eur Heart J. 2010;31:2501–2555.
3. Horie H, Takahashi M, Minai K. Long-term beneficial effect of late reperfusion for acute anterior myocardial infarction with percutaneous transluminal coronary angioplasty. Circulation. 1998;98:2377–2382.

Funding

No data provided

Supplemental files

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Additional information

Competing interests

No competing interests were disclosed.

Data availability statement

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

Creative Commons license

Copyright © 2022 Adhyapak et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.