Disparities in Cardio-Oncology Strategically Focused Research Network

Grant Name
Disparities in Cardio-Oncology Strategically Focused Research Network
Funder
American Heart Association (AHA)
Location
United States
Research Area
Cancer Prevention
Cardiology
Cardiovascular Disease
Health Disparities
Health of Underserved Populations
Oncology
Deadline
February 9, 2022
Grant Size
Upper $2,925,000USD Duration: 4 years with opportunity for up to 12-months No-Cost Extension (NCE). Number of Awards: AHA anticipates awarding four (4) Center grants* to establish the Disparities in CardioOncology SFRN. Awardees will be selected based on scientific merit and how each group aligns with AHA’s mission and goals. *The AHA reserves the right to determine the final number of awardees. Award Amount: The maximum budget amount a Center applicant may request is $2,925,000. The AHA reserves the right to determine the final award amount for competitive projects based on need and potential impact.
Contact Info
SFRN@heart.org
Website
Eligibility
Applicants to AHA SFRN award mechanisms, the Center Director and each project PI must be an AHA Member/Partner. AHA SFRN awards are limited to U.S.-based non-profit institutions, including medical, osteopathic and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals and others that can demonstrate the ability to conduct the proposed research.
Description
Cardio-oncology represents the intersection of cancer and cardiovascular disease. It has emerged as a new research area as a result of the evolution in cancer therapies which have improved prognosis for many cancer patients. Cardiovascular complications from cancer therapies represent an important challenge for many cancer patients, both at the time of treatment as well as during survivorship. To address critical deficiencies related to disparities in cardio-oncology, AHA has prioritized funding research that increases the understanding of the etiology, pathophysiology, treatment and prevention of cardiovascular disease among cancer patients and cancer survivors from diverse populations. Cancer patients and/or survivors are often not included in cardiovascular studies. Understanding mechanistic underpinnings of cardiac complications, especially targeted and immune-based therapies, can lead to better diagnostic, preventive and treatment strategies. Furthermore, data describing differences in cardiovascular toxicities associated with cancer therapies are sparse. This SFRN provides the AHA with a mechanism to advance the understanding of the causes, pathophysiology, risk factors, epidemiology, prevention and treatment of cardiovascular disease in those patients who are currently undergoing or have undergone cancer treatment (or applicable models). Applicants are requested to focus in particular on areas that have not been previously explored in cardiooncology, and must include diverse and/or underrepresented cohorts in proposed studies. The intent of this initiative is to support a collaboration of basic, clinical and population (or implementation) researchers whose collective efforts will lead to new approaches to the study of cardiooncology. Each Center must propose two (2) or three (3) projects representing at least two of the following research disciplines: basic, clinical, and population science. All projects must focus on disparities in cardiooncology. Population studies are inclusive of projects ranging from cohort studies to translational or implementation research involving community interventions. All projects must address health and health care disparities and/or health equity in the cardio-oncology domain. Eligibility Applicants to AHA SFRN award mechanisms, the Center Director and each project PI must be an AHA Member/Partner. AHA SFRN awards are limited to U.S.-based non-profit institutions, including medical, osteopathic and dental schools, veterinary schools, schools of public health, pharmacy schools, nursing schools, universities and colleges, public and voluntary hospitals and others that can demonstrate the ability to conduct the proposed research.

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February 9, 2022

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