Small molecule drug discovery for Dengue and West Nile viruses: applying experience from hepatitis C virus
出版年份 2010 全文链接
标题
Small molecule drug discovery for Dengue and West Nile viruses: applying experience from hepatitis C virus
作者
关键词
-
出版物
Future Medicinal Chemistry
Volume 2, Issue 7, Pages 1181-1203
出版商
Future Science, LTD
发表日期
2010-07-12
DOI
10.4155/fmc.10.195
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification
- (2010) Scott J. Balsitis et al. PLoS Pathogens
- Review article: investigational agents for chronic hepatitis C
- (2009) A. J. V. THOMPSON et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity against Flaviviruses
- (2009) J. Chang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Preclinical Characterization of PF-00868554, a Potent Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase
- (2009) S. T. Shi et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Small-Molecule Dengue Virus Entry Inhibitor
- (2009) Q.-Y. Wang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Flaviviral methyltransferase/RNA interaction: Structural basis for enzyme inhibition
- (2009) Mario Milani et al. ANTIVIRAL RESEARCH
- Identification and characterization of inhibitors of West Nile virus
- (2009) Francesc Puig-Basagoiti et al. ANTIVIRAL RESEARCH
- Structure-based discovery of dengue virus protease inhibitors
- (2009) Suzanne M. Tomlinson et al. ANTIVIRAL RESEARCH
- Antiviral activity of geneticin against dengue virus
- (2009) Xianchao G. Zhang et al. ANTIVIRAL RESEARCH
- A heterocyclic molecule with significant activity against dengue virus
- (2009) Vasu Nair et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structure–activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase
- (2009) Shyama Sidique et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication
- (2009) Andrew W. Tai et al. Cell Host & Microbe
- RNA-dependent RNA polymerases from Flaviviridae
- (2009) Kyung H Choi et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Targeting the non-structural proteins of hepatitis C virus: beyond hepatitis C virus protease and polymerase
- (2009) Tod P Holler et al. Expert Opinion on Drug Discovery
- Progress towards improving antiviral therapy for hepatitis C with hepatitis C virus polymerase inhibitors. Part I: Nucleoside analogues
- (2009) Nathaniel A Brown EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection
- (2009) Pierre L Beaulieu EXPERT OPINION ON THERAPEUTIC PATENTS
- NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease
- (2009) Xun-Cheng Su et al. FEBS Journal
- Identification of novel target sites and an inhibitor of the dengue virus E protein
- (2009) Ragothaman Yennamalli et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Safety and efficacy of viramidine versus ribavirin in ViSER2: Randomized, double-blind study in therapy-naive hepatitis C patients
- (2009) Patrick Marcellin et al. JOURNAL OF HEPATOLOGY
- N-Sulfonylanthranilic Acid Derivatives as Allosteric Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase
- (2009) Zheng Yin et al. JOURNAL OF MEDICINAL CHEMISTRY
- Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion
- (2009) V. Nayak et al. JOURNAL OF VIROLOGY
- Progress towards a dengue vaccine
- (2009) Daniel P Webster et al. LANCET INFECTIOUS DISEASES
- An adenosine nucleoside inhibitor of dengue virus
- (2009) Z. Yin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A genome-wide genetic screen for host factors required for hepatitis C virus propagation
- (2009) Q. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intravenous immunoglobulins in the treatment of dengue illness
- (2009) Senaka Rajapakse TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
- Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication
- (2009) Frédéric H. Vaillancourt et al. VIROLOGY
- Hepatitis C Virus entry: the early steps in the viral replication cycle
- (2009) Ali Sabahi Virology Journal
- Discovery of a Non-Peptidic Inhibitor of West Nile Virus NS3 Protease by High-Throughput Docking
- (2009) Dariusz Ekonomiuk et al. PLoS Neglected Tropical Diseases
- Peptidomimetic Therapeutic Agents Targeting the Protease Enzyme of the Human Immunodeficiency Virus and Hepatitis C Virus
- (2008) Youla S. Tsantrizos ACCOUNTS OF CHEMICAL RESEARCH
- Antiviral Compounds Discovered by Virtual Screening of Small−Molecule Libraries against Dengue Virus E Protein
- (2008) Zhigang Zhou et al. ACS Chemical Biology
- Identification and Biochemical Characterization of Small-Molecule Inhibitors of West Nile Virus Serine Protease by a High-Throughput Screen
- (2008) N. H. Mueller et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In vitro inhibition of dengue virus entry by p-sulfoxy-cinnamic acid and structurally related combinatorial chemistries
- (2008) C REES et al. ANTIVIRAL RESEARCH
- West Nile Virus NS2B/NS3 Protease As An Antiviral Target
- (2008) K. Chappell et al. CURRENT MEDICINAL CHEMISTRY
- Present perspectives on flaviviral chemotherapy
- (2008) Debapriya Ghosh et al. DRUG DISCOVERY TODAY
- Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein
- (2008) Dahai Luo et al. EMBO JOURNAL
- HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti-hepatitis C virus activity In Vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus
- (2008) Norman M. Kneteman et al. HEPATOLOGY
- Understanding the contribution of cellular immunity to dengue disease pathogenesis
- (2008) Anuja Mathew et al. IMMUNOLOGICAL REVIEWS
- Design, Synthesis, and Biological Evaluation of Antiviral Agents Targeting Flavivirus Envelope Proteins
- (2008) Ze Li et al. JOURNAL OF MEDICINAL CHEMISTRY
- Potent Cationic Inhibitors of West Nile Virus NS2B/NS3 Protease With Serum Stability, Cell Permeability and Antiviral Activity
- (2008) Martin J. Stoermer et al. JOURNAL OF MEDICINAL CHEMISTRY
- Analysis of Flavivirus NS5 Methyltransferase Cap Binding
- (2008) Brian J. Geiss et al. JOURNAL OF MOLECULAR BIOLOGY
- West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism
- (2008) H. Dong et al. JOURNAL OF VIROLOGY
- The Mannose Receptor Mediates Dengue Virus Infection of Macrophages
- (2008) Joanna L. Miller et al. PLoS Pathogens
- DC-SIGN enhances infection of cells with glycosylated West Nile virus in vitro and virus replication in human dendritic cells induces production of IFN-α and TNF-α
- (2008) Byron E.E. Martina et al. VIRUS RESEARCH
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