标题
The hallmarks of Parkinson's disease
作者
关键词
-
出版物
FEBS Journal
Volume 280, Issue 23, Pages 5981-5993
出版商
Wiley
发表日期
2013-05-11
DOI
10.1111/febs.12335
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Light microscopy applications in systems biology: opportunities and challenges
- (2013) Paul Michel Aloyse Antony et al. Cell Communication and Signaling
- The genetics of Parkinson's disease: Progress and therapeutic implications
- (2013) Andrew B. Singleton et al. MOVEMENT DISORDERS
- The pathology roadmap in Parkinson disease
- (2013) D. James Surmeier et al. Prion
- Mitochondrial Biology and Parkinson's Disease
- (2013) C. Perier et al. Cold Spring Harbor Perspectives in Medicine
- Genetics of Parkinson's Disease
- (2013) C. Klein et al. Cold Spring Harbor Perspectives in Medicine
- Somatic mitochondrial DNA mutations in early parkinson and incidental lewy body disease
- (2012) Michael T. Lin et al. ANNALS OF NEUROLOGY
- Induced pluripotent stem cell research: A revolutionary approach to face the challenges in drug screening
- (2012) Minjung Song et al. ARCHIVES OF PHARMACAL RESEARCH
- Lysosomal dysfunction in Parkinson disease
- (2012) Benjamin Dehay et al. Autophagy
- Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease
- (2012) Helen Ling et al. BRAIN
- From α-synuclein to synaptic dysfunctions: New insights into the pathophysiology of Parkinson's disease
- (2012) Arianna Bellucci et al. BRAIN RESEARCH
- PLA2G6 Mutations and Other Rare Causes of Neurodegeneration with Brain Iron Accumulation
- (2012) Alisdair McNeill CURRENT DRUG TARGETS
- Chelating Agents for Neurodegenerative Diseases
- (2012) R. J. Ward et al. CURRENT MEDICINAL CHEMISTRY
- Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences
- (2012) Nicole Exner et al. EMBO JOURNAL
- Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease
- (2012) Zhi Yao et al. JOURNAL OF CELL SCIENCE
- Neuronal vulnerability, pathogenesis, and Parkinson's disease
- (2012) David Sulzer et al. MOVEMENT DISORDERS
- Parkinson's disease: Evidence for environmental risk factors
- (2012) Karl Kieburtz et al. MOVEMENT DISORDERS
- Identifying prodromal Parkinson's disease: Pre-Motor disorders in Parkinson's disease
- (2012) Ronald B. Postuma et al. MOVEMENT DISORDERS
- Living on the edge with too many mouths to feed: Why dopamine neurons die
- (2012) J. Paul Bolam et al. MOVEMENT DISORDERS
- Astrocyte-derived GDNF is a potent inhibitor of microglial activation
- (2012) Sandra Moreira Rocha et al. NEUROBIOLOGY OF DISEASE
- Iron dysregulation in movement disorders
- (2012) Petr Dusek et al. NEUROBIOLOGY OF DISEASE
- Genetics and iron in the systems biology of Parkinson’s disease and some related disorders
- (2012) Claudia Funke et al. NEUROCHEMISTRY INTERNATIONAL
- Monogenic Mitochondrial Disorders
- (2012) Werner J.H. Koopman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice
- (2012) Francisco Pan-Montojo et al. Scientific Reports
- PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
- (2012) Kahori Shiba-Fukushima et al. Scientific Reports
- Solvent exposures and parkinson disease risk in twins
- (2011) Samuel M. Goldman et al. ANNALS OF NEUROLOGY
- Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
- (2011) Jisun Lee et al. BIOCHEMICAL JOURNAL
- Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies
- (2011) Joseph R. Mazzulli et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- From Systems Biology to Systems Biomedicine
- (2011) Paul MA Antony et al. CURRENT OPINION IN BIOTECHNOLOGY
- Epidemiology and etiology of Parkinson’s disease: a review of the evidence
- (2011) Karin Wirdefeldt et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Parkinson disease: Insights in clinical, genetic and pathological features of monogenic disease subtypes
- (2011) David Crosiers et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Parkinson’s disease mouse models in translational research
- (2011) Paul M. A. Antony et al. MAMMALIAN GENOME
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line
- (2011) Lydia Alvarez-Erviti et al. NEUROSCIENCE RESEARCH
- Neuroinflammation in Parkinson's disease
- (2011) Etienne C. Hirsch et al. PARKINSONISM & RELATED DISORDERS
- Bidirectional Coupling between Astrocytes and Neurons Mediates Learning and Dynamic Coordination in the Brain: A Multiple Modeling Approach
- (2011) John J. Wade et al. PLoS One
- Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease
- (2011) Andrey Yurevich Abramov et al. PLoS One
- Introduction to Network Analysis in Systems Biology
- (2011) A. Ma'ayan Science Signaling
- Ageing, neurodegeneration and Parkinson's disease
- (2010) J. V. Hindle AGE AND AGEING
- The Nrf2-Keap1-ARE Signaling Pathway: The Regulation and Dual Function of Nrf2 in Cancer
- (2010) Donna D. Zhang ANTIOXIDANTS & REDOX SIGNALING
- Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples
- (2010) Douglas B. Kell ARCHIVES OF TOXICOLOGY
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- Neuron-glia metabolic coupling and plasticity
- (2010) Pierre J. Magistretti EXPERIMENTAL PHYSIOLOGY
- Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease
- (2010) Ashley D. Reynolds et al. JOURNAL OF IMMUNOLOGY
- Increased iron levels correlate with the selective nigral dopaminergic neuron degeneration in Parkinson’s disease
- (2010) Zhanyun Lv et al. JOURNAL OF NEURAL TRANSMISSION
- Metals, oxidative stress and neurodegenerative disorders
- (2010) Klaudia Jomova et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- ATP13A2 mutations (PARK9) cause neurodegeneration with brain iron accumulation
- (2010) Susanne A. Schneider et al. MOVEMENT DISORDERS
- What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them?
- (2010) David A. Gallagher et al. MOVEMENT DISORDERS
- A molecular basis for the increased vulnerability of substantia nigra dopamine neurons in aging and Parkinson's disease
- (2010) C. Savio Chan et al. MOVEMENT DISORDERS
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
- (2010) Taye H Hamza et al. NATURE GENETICS
- Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
- (2010) Venu M. Nemani et al. NEURON
- Oxidative Stress Induction of DJ-1 Protein in Reactive Astrocytes Scavenges Free Radicals and Reduces Cell Injury
- (2010) Takashi Yanagida et al. Oxidative Medicine and Cellular Longevity
- Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice
- (2010) Francisco Pan-Montojo et al. PLoS One
- An energy systems approach to Parkinson's disease
- (2010) Peter Wellstead et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Parkinson's Disease
- (2009) Christopher H. Hawkes et al. Annals of the New York Academy of Sciences
- Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice
- (2009) Takumi Satoh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease
- (2009) Elke Hattingen et al. BRAIN
- Regulation of astrocyte inflammatory responses by the Parkinson’s disease-associated gene DJ-1
- (2009) Jens Waak et al. FASEB JOURNAL
- Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems
- (2009) Viktor I. Korolchuk et al. FEBS LETTERS
- Non-motor symptoms in Parkinson’s disease
- (2009) Ariane Park et al. JOURNAL OF NEUROLOGY
- Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum
- (2009) W. Matsuda et al. JOURNAL OF NEUROSCIENCE
- The control systems structures of energy metabolism
- (2009) M. Cloutier et al. Journal of the Royal Society Interface
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions
- (2009) Yaping Chu et al. NEUROBIOLOGY OF DISEASE
- Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
- (2009) Kurt M. Lucin et al. NEURON
- Silencing of PINK1 Expression Affects Mitochondrial DNA and Oxidative Phosphorylation in DOPAMINERGIC Cells
- (2009) Matthew E. Gegg et al. PLoS One
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Is Parkinson's disease a prion disorder?
- (2009) C. W. Olanow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuronal regulation of immune responses in the central nervous system
- (2009) Li Tian et al. TRENDS IN IMMUNOLOGY
- Tripartite synapses: astrocytes process and control synaptic information
- (2009) Gertrudis Perea et al. TRENDS IN NEUROSCIENCES
- Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease
- (2008) Luigi Zecca et al. ACTA NEUROPATHOLOGICA
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
- Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction
- (2008) Hwan-Ching Tai et al. NATURE REVIEWS NEUROSCIENCE
- Glial Cells as Players in Parkinsonism: The “Good,” the “Bad,” and the “Mysterious” Glia
- (2008) Maria A. Mena et al. NEUROSCIENTIST
- Oxidative insults induce DJ-1 upregulation and redistribution: Implications for neuroprotection
- (2008) Nirit Lev et al. NEUROTOXICOLOGY
- Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity
- (2007) Don M. Gash et al. ANNALS OF NEUROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started