TGFβ1 evokes myoblast apoptotic response via a novel signaling pathway involving S1P4 transactivation upstream of Rho-kinase-2 activation

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases

(2012) Yoh Takuwa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer

(2012) J Ohotski et al.   BRITISH JOURNAL OF CANCER

Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

(2012) Jerry E. Chipuk et al.   CELL

TGFβ signaling

(2012) Elizabeth M. MacDonald et al.   CURRENT OPINION IN RHEUMATOLOGY

The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function

(2012) A. Nijnik et al.   JOURNAL OF IMMUNOLOGY

An inhibitor of transforming growth factor beta type I receptor ameliorates muscle atrophy in a mouse model of caveolin 3-deficient muscular dystrophy

(2012) Yutaka Ohsawa et al.   LABORATORY INVESTIGATION

Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-α2-deficient congenital muscular dystrophy (MDC1A)

(2012) Sarina Meinen et al.   Skeletal Muscle

Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate

(2011) Yugesh Kharel et al.   BIOCHEMICAL JOURNAL

Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P4) receptor antagonists

(2011) Miguel Guerrero et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists

(2011) Miguel Guerrero et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Development of Amidine-Based Sphingosine Kinase 1 Nanomolar Inhibitors and Reduction of Sphingosine 1-Phosphate in Human Leukemia Cells

(2011) Andrew J. Kennedy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Role of TGF-β signaling in inherited and acquired myopathies

(2011) Tyesha N Burks et al.   Skeletal Muscle

Aberrant repair and fibrosis development in skeletal muscle

(2011) Christopher J Mann et al.   Skeletal Muscle

Sphingosine kinase-1/S1P1 signalling axis negatively regulates mitogenic response elicited by PDGF in mouse myoblasts

(2010) Paola Nincheri et al.   CELLULAR SIGNALLING

Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4

(2010) Sven Golfier et al.   FASEB JOURNAL

Sphingosine Kinase Mediates Resistance to the Synthetic RetinoidN-(4-Hydroxyphenyl)retinamide in Human Ovarian Cancer Cells

(2010) Giuditta Illuzzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TIEG1 negatively controls the myoblast pool indispensable for fusion during myogenic differentiation of C2C12 cells

(2010) Masato Miyake et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting Fibrosis in Duchenne Muscular Dystrophy

(2010) Lan Zhou et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Transforming Growth Factor-β1 Induces Transdifferentiation of Myoblasts into Myofibroblasts via Up-Regulation of Sphingosine Kinase-1/S1P3 Axis

(2010) Francesca Cencetti et al.   MOLECULAR BIOLOGY OF THE CELL

Export and functions of sphingosine-1-phosphate

(2009) Roger H. Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

(2009) S. Vemula et al.   BLOOD

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor- -stimulated collagen production by cardiac fibroblasts

(2009) N. Gellings Lowe et al.   CARDIOVASCULAR RESEARCH

TGF-β Superfamily Signaling in Embryonic Development and Homeostasis

(2009) Mary Y. Wu et al.   DEVELOPMENTAL CELL

Transforming growth factor- 1-induced satellite cell apoptosis in chickens is associated with  1 integrin-mediated focal adhesion kinase activation

(2009) X. Li et al.   POULTRY SCIENCE

Role of transforming growth factor-β superfamily signaling pathways in human disease

(2008) Kelly J. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Pleiotropic effects of sphingolipids in skeletal muscle

(2008) P. Bruni et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

TGFβ protects mesoangioblasts from apoptosis via sphingosine kinase-1 regulation

(2008) Chiara Donati et al.   CELLULAR SIGNALLING

Thematic Review Series: Sphingolipids.Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling,

(2008) Deborah A. Lebman et al.   JOURNAL OF LIPID RESEARCH

Sphingosine Kinases and Sphingosine-1-Phosphate Are Critical for Transforming Growth Factor  -Induced Extracellular Signal-Regulated Kinase 1 and 2 Activation and Promotion of Migration and Invasion of Esophageal Cancer Cells

(2008) A. V. Miller et al.   MOLECULAR AND CELLULAR BIOLOGY