Advances in the therapy of Alzheimer’s disease: targeting amyloid beta and tau and perspectives for the future
出版年份 2014 全文链接
标题
Advances in the therapy of Alzheimer’s disease: targeting amyloid beta and tau and perspectives for the future
作者
关键词
-
出版物
Expert Review of Neurotherapeutics
Volume 15, Issue 1, Pages 83-105
出版商
Informa UK Limited
发表日期
2014-12-24
DOI
10.1586/14737175.2015.995637
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- In vivo tau imaging: Obstacles and progress
- (2014) Victor L. Villemagne et al. Alzheimers & Dementia
- Rethinking the Food and Drug Administration's 2013 guidance on developing drugs for early-stage Alzheimer's disease
- (2014) Lon S. Schneider Alzheimers & Dementia
- Florbetapir (18F) for brain amyloid positron emission tomography: Highlights on the European marketing approval
- (2014) Anabel Cortes-Blanco et al. Alzheimers & Dementia
- Alzheimer's disease research and development: a call for a new research roadmap
- (2014) Howard H. Feldman et al. Annals of the New York Academy of Sciences
- Apolipoprotein E in Alzheimer's Disease: An Update
- (2014) Jin-Tai Yu et al. Annual Review of Neuroscience
- Alzheimer’s disease from researcher to caregiver: a personal journey and call to action
- (2014) Diane Stephenson Expert Review of Neurotherapeutics
- Harmonized diagnostic criteria for Alzheimer's disease: recommendations
- (2014) J. C. Morris et al. JOURNAL OF INTERNAL MEDICINE
- Advances in the prevention of Alzheimer's disease and dementia
- (2014) A. Solomon et al. JOURNAL OF INTERNAL MEDICINE
- Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014
- (2014) L. S. Schneider et al. JOURNAL OF INTERNAL MEDICINE
- Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling
- (2014) N. S. Woodling et al. JOURNAL OF NEUROSCIENCE
- A population perspective on the IWG-2 research diagnostic criteria for Alzheimer's disease
- (2014) Carol Brayne LANCET NEUROLOGY
- Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
- (2014) Bruno Dubois et al. LANCET NEUROLOGY
- Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
- (2014) Stephen Salloway et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
- (2014) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- The A4 Study: Stopping AD Before Symptoms Begin?
- (2014) R. A. Sperling et al. Science Translational Medicine
- The Preclinical Alzheimer Cognitive Composite
- (2014) Michael C. Donohue et al. JAMA Neurology
- CSF biomarker variability in the Alzheimer's Association quality control program
- (2013) Niklas Mattsson et al. Alzheimers & Dementia
- Designing drug trials for Alzheimer’s disease: What we have learned from the release of the phase III antibody trials: A report from the EU/US/CTAD Task Force
- (2013) Bruno Vellas et al. Alzheimers & Dementia
- The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER): Study design and progress
- (2013) Miia Kivipelto et al. Alzheimers & Dementia
- CSF Aβ1-42 combined with neuroimaging biomarkers in the early detection, diagnosis and prediction of Alzheimer's disease
- (2013) Simone Lista et al. Alzheimers & Dementia
- Tau-aggregation inhibitor therapy for Alzheimer's disease
- (2013) Claude M. Wischik et al. BIOCHEMICAL PHARMACOLOGY
- Immunotherapy in Alzheimer’s Disease: Do We Have All the Pieces of the Puzzle?
- (2013) Marie Sarazin et al. BIOLOGICAL PSYCHIATRY
- Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue
- (2013) Jun-Xia Lu et al. CELL
- Between new genetic discoveries and large randomized trials—neurological research in the era of systems medicine
- (2013) Thomas Misgeld et al. EMBO REPORTS
- Regulatable transgenic mouse models of Alzheimer disease: onset, reversibility and spreading of Tau pathology
- (2013) Katja Hochgräfe et al. FEBS Journal
- A concise radiosynthesis of the tau radiopharmaceutical, [18F]T807
- (2013) Timothy M. Shoup et al. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
- Passive immunotherapy for Alzheimer’s disease: What have we learned, and where are we headed?
- (2013) P. S. Aisen et al. Journal of Nutrition Health & Aging
- Immunotherapy against amyloid pathology in Alzheimer's disease
- (2013) Daniela Galimberti et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II
- (2013) Fiona E Matthews et al. LANCET
- Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study
- (2013) Stephanie JB Vos et al. LANCET NEUROLOGY
- Moving towards early clinical trials for amyloid-targeted therapy in Alzheimer's disease
- (2013) Paul S. Aisen et al. NATURE REVIEWS DRUG DISCOVERY
- Alzheimer disease therapy—moving from amyloid-β to tau
- (2013) Ezio Giacobini et al. Nature Reviews Neurology
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later
- (2013) C. M. Roe et al. NEUROLOGY
- Twenty-year changes in dementia occurrence suggest decreasing incidence in central Stockholm, Sweden
- (2013) C. Qiu et al. NEUROLOGY
- Regulatory Innovation and Drug Development for Early-Stage Alzheimer's Disease
- (2013) Nicholas Kozauer et al. NEW ENGLAND JOURNAL OF MEDICINE
- New Insights into the Dementia Epidemic
- (2013) Eric B. Larson et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease
- (2013) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- MRI and cerebrospinal fluid biomarkers for predicting progression to Alzheimer's disease in patients with mild cognitive impairment: a diagnostic accuracy study
- (2013) Edo Richard et al. BMJ Open
- Amyloid PET in clinical practice: Its place in the multidimensional space of Alzheimer's disease
- (2013) Rik Vandenberghe et al. NeuroImage-Clinical
- Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease
- (2013) Gaël Chételat et al. NeuroImage-Clinical
- The A4 trial: Anti-amyloid treatment of asymptomatic Alzheimer's disease
- (2012) Reisa Sperling et al. Alzheimers & Dementia
- Safety and biomarker effects of solanezumab in patients with Alzheimer’s disease
- (2012) Martin Farlow et al. Alzheimers & Dementia
- Development of biomarkers to chart all Alzheimer’s disease stages: The royal road to cutting the therapeutic Gordian Knot
- (2012) Harald Hampel et al. Alzheimers & Dementia
- Systematic review of the body of evidence for the use of biomarkers in the diagnosis of dementia
- (2012) Anna H. Noel-Storr et al. Alzheimers & Dementia
- Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach
- (2012) Nadege Zommer et al. Current Alzheimer Research
- Therapeutic strategies for tau mediated neurodegeneration
- (2012) Y. Yoshiyama et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Recruitment strategies for preventive trials. The MAPT study (Multidomain Alzheimer Preventive Trial)
- (2012) I. Carrie et al. Journal of Nutrition Health & Aging
- Genetic insights in Alzheimer's disease
- (2012) Karolien Bettens et al. LANCET NEUROLOGY
- Targeting Synaptic Dysfunction in Alzheimer’s Disease Therapy
- (2012) Robert Nisticò et al. MOLECULAR NEUROBIOLOGY
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- Down's syndrome and Alzheimer's disease: towards secondary prevention
- (2012) Seth Ness et al. NATURE REVIEWS DRUG DISCOVERY
- Alzheimer's disease market: hope deferred
- (2012) Zelicia Gerald et al. NATURE REVIEWS DRUG DISCOVERY
- Preclinical Alzheimer disease—the challenges ahead
- (2012) Reisa A. Sperling et al. Nature Reviews Neurology
- From inherited to sporadic AD—crossing the biomarker bridge
- (2012) Harald Hampel et al. Nature Reviews Neurology
- Is dementia incidence declining?: Trends in dementia incidence since 1990 in the Rotterdam Study
- (2012) E. M. C. Schrijvers et al. NEUROLOGY
- Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
- (2012) Randall J. Bateman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Dementia prevention: current epidemiological evidence and future perspective
- (2012) Francesca Mangialasche et al. Alzheimers Research & Therapy
- Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Reisa A. Sperling et al. Alzheimers & Dementia
- The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Marilyn S. Albert et al. Alzheimers & Dementia
- Chronic Divalproex Sodium to Attenuate Agitation and Clinical Progression of Alzheimer Disease
- (2011) Pierre N. Tariot ARCHIVES OF GENERAL PSYCHIATRY
- Risk Factors and Preventive Interventions for Alzheimer Disease
- (2011) Martha L. Daviglus ARCHIVES OF NEUROLOGY
- Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models
- (2011) Xiyun Chai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ‘Clinical trials in Alzheimer’s disease’: immunotherapy approaches
- (2011) Julien Delrieu et al. JOURNAL OF NEUROCHEMISTRY
- Progress in the development of new drugs in Alzheimer’s disease
- (2011) Antoine Piau et al. Journal of Nutrition Health & Aging
- The projected effect of risk factor reduction on Alzheimer's disease prevalence
- (2011) Deborah E Barnes et al. LANCET NEUROLOGY
- Chronic divalproex sodium use and brain atrophy in Alzheimer disease
- (2011) A. S. Fleisher et al. NEUROLOGY
- Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift
- (2011) Todd E. Golde et al. NEURON
- Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice
- (2011) Mian Bi et al. PLoS One
- Testing the Right Target and Right Drug at the Right Stage
- (2011) R. A. Sperling et al. Science Translational Medicine
- Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia
- (2011) Michael Ewers et al. TRENDS IN NEUROSCIENCES
- Tau transgenic rat model and response to tau vaccine
- (2010) Michal Novak Alzheimers & Dementia
- Safety and Changes in Plasma and Cerebrospinal Fluid Amyloid β After a Single Administration of an Amyloid β Monoclonal Antibody in Subjects With Alzheimer Disease
- (2010) Eric R. Siemers et al. CLINICAL NEUROPHARMACOLOGY
- Revising the definition of Alzheimer's disease: a new lexicon
- (2010) Bruno Dubois et al. LANCET NEUROLOGY
- Alzheimer's disease: clinical trials and drug development
- (2010) Francesca Mangialasche et al. LANCET NEUROLOGY
- Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives
- (2010) Harald Hampel et al. NATURE REVIEWS DRUG DISCOVERY
- Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
- (2010) Lars M. Ittner et al. NATURE REVIEWS NEUROSCIENCE
- Nature versus Nurture: Death of a Dogma, and the Road Ahead
- (2010) Bryan J. Traynor et al. NEURON
- The Genetics of Alzheimer Disease: Back to the Future
- (2010) Lars Bertram et al. NEURON
- Prevention of Dementia by Intensive Vascular Care (PreDIVA)
- (2009) Edo Richard et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Identification, characterization, and comparison of amino-terminally truncated Aβ 42 peptides in Alzheimer's disease brain tissue and in plasma from Alzheimer's patients receiving solanezumab immunotherapy treatment
- (2009) Ronald B. DeMattos et al. Alzheimers & Dementia
- Tau vaccine: Active immunization with misfolded tau protein attenuates tau pathology in the transgenic rat model of tauopathy
- (2009) Michal Novak Alzheimers & Dementia
- Commentary on “A roadmap for the prevention of dementia II. Leon Thal Symposium 2008.” The Multidomain Alzheimer Preventive Trial (MAPT): A new approach to the prevention of Alzheimer's disease
- (2009) Sophie Gillette-Guyonnet et al. Alzheimers & Dementia
- Methylene blue and Alzheimer's disease
- (2009) Murat Oz et al. BIOCHEMICAL PHARMACOLOGY
- Secretase inhibitors and modulators for Alzheimer’s disease treatment
- (2009) Taisuke Tomita Expert Review of Neurotherapeutics
- Lithium Trial in Alzheimer's Disease
- (2009) Harald Hampel et al. JOURNAL OF CLINICAL PSYCHIATRY
- Challenges in the conduct of disease-modifying trials in ad: Practical experience from a phase 2 trial of TAU-aggregation inhibitor therapy
- (2009) C. Wischik et al. Journal of Nutrition Health & Aging
- Effect of tramiprosate in patients with mild-to-moderate alzheimer’s disease: Exploratory analyses of the MRI sub-group of the alphase study
- (2009) S. Gauthier et al. Journal of Nutrition Health & Aging
- A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
- (2009) S. Salloway et al. NEUROLOGY
- Trends in the prevalence and mortality of cognitive impairment in the United States: Is there evidence of a compression of cognitive morbidity?
- (2008) Kenneth M. Langa et al. Alzheimers & Dementia
- A feasibility and tolerability study of lithium in Alzheimer's disease
- (2008) Alastair Macdonald et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Immunotherapy Reduces Vascular Amyloid- in PDAPP Mice
- (2008) S. Schroeter et al. JOURNAL OF NEUROSCIENCE
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now