Delivery of host cell-directed therapeutics for intracellular pathogen clearance

One pot synthesis of gold nanoparticles and application in chemotherapy of wild and resistant type visceral leishmaniasis

(2013) Suvadra Das et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

TLR agonists: our best frenemy in cancer immunotherapy

(2013) Sabina Kaczanowska et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Electrospray Encapsulation of Toll-Like Receptor Agonist Resiquimod in Polymer Microparticles for the Treatment of Visceral Leishmaniasis

(2013) Anthony D. Duong et al.   MOLECULAR PHARMACEUTICS

Efficient Delivery of the Toll-like Receptor Agonists Polyinosinic:Polycytidylic Acid and CpG to Macrophages by Acetalated Dextran Microparticles

(2013) Kevin J. Peine et al.   MOLECULAR PHARMACEUTICS

Tuberculosis

(2013) Alimuddin Zumla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection

(2013) B. G. Byrne et al.   mBio

Polycation-based nanoparticle delivery of RNAi therapeutics: Adverse effects and solutions

(2012) Borja Ballarín-González et al.   ADVANCED DRUG DELIVERY REVIEWS

Unfolded protein response to autophagy as a promising druggable target for anticancer therapy

(2012) Dong Hoon Suh et al.   Annals of the New York Academy of Sciences

Recognition of Bacteria by Inflammasomes

(2012) Jakob von Moltke et al.   Annual Review of Immunology

Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus

(2012) Hao-Chieh Chiu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Leishmaniasis: Prevention, Parasite Detection and Treatment

(2012) T. Kobets et al.   CURRENT MEDICINAL CHEMISTRY

Resiquimod, a topical drug for viral skin lesions and skin cancer

(2012) Thomas Meyer et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Toll-Like Receptor 2 Ligand Pretreatment Attenuates Retinal Microglial Inflammatory Response but Enhances Phagocytic Activity toward Staphylococcus aureus

(2012) Travis Kochan et al.   INFECTION AND IMMUNITY

Delivery system for the enhanced efficiency of immunostimulatory nucleic acids

(2012) Anže Smole et al.   Innate Immunity

Enhanced stability of horseradish peroxidase encapsulated in acetalated dextran microparticles stored outside cold chain conditions

(2012) Naveen Kanthamneni et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Potential of NOD receptor ligands as immunomodulators in particulate vaccine carriers

(2012) Christian Wischke et al.   JOURNAL OF CONTROLLED RELEASE

The big picture on nanomedicine: the state of investigational and approved nanomedicine products

(2012) Michael L. Etheridge et al.   Nanomedicine-Nanotechnology Biology and Medicine

Proof of concept for next-generation nanoparticle drugs in humans

(2012) Cormac Sheridan   NATURE BIOTECHNOLOGY

Immunomodulatory effect of R848 on cytokine production associated with Schistosoma mansoni infection

(2012) Ghada Boghdadi et al.   PARASITOLOGY RESEARCH

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective

(2011) S.M. Moghimi et al.   Annual Review of Pharmacology and Toxicology

Adjuvanted, antigen loaded N-trimethyl chitosan nanoparticles for nasal and intradermal vaccination: Adjuvant- and site-dependent immunogenicity in mice

(2011) Suzanne M. Bal et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Triggering Receptor Expressed on Myeloid cells-1 (TREM-1) Modulates Immune Responses toAspergillus fumigatusDuring Fungal Asthma in Mice

(2011) Karen F. Buckland et al.   IMMUNOLOGICAL INVESTIGATIONS

Tuberculosis

(2011) Stephen D Lawn et al.   LANCET

Immunopathogenesis of Staphylococcus aureus pulmonary infection

(2011) Dane Parker et al.   Seminars in Immunopathology

The benefits and challenges associated with the use of drug delivery systems in cancer therapy

(2010) Edna Cukierman et al.   BIOCHEMICAL PHARMACOLOGY

Toll-Like Receptor 3 Agonist Protection against Experimental Francisella tularensis Respiratory Tract Infection

(2010) R. B. Pyles et al.   INFECTION AND IMMUNITY

Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone

(2010) S.S. Costa et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

CpG oligodeoxynucleotide augments the antileishmanial activity of miltefosine against experimental visceral leishmaniasis

(2010) Shraddha A. Sane et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

TLR9-Targeted Biodegradable Nanoparticles as Immunization Vectors Protect against West Nile Encephalitis

(2010) S. L. Demento et al.   JOURNAL OF IMMUNOLOGY

Microencapsulation of budesonide with dextran by spray drying technique for colon-targeted delivery: anin vitro/in vivoevaluation in induced colitis in rat

(2010) Jaleh Varshosaz et al.   JOURNAL OF MICROENCAPSULATION

In Vitro Analysis of Acetalated Dextran Microparticles as a Potent Delivery Platform for Vaccine Adjuvants

(2010) Eric M. Bachelder et al.   MOLECULAR PHARMACEUTICS

Half-century-old TB drugs get a facelift in new cocktails

(2010) Stu Hutson   NATURE MEDICINE

Nanoparticle Trojan Horses Gallop From the Lab Into the Clinic

(2010) R. F. Service   SCIENCE

Use of CpG oligonucleotides in treatment of asthma and allergic disease

(2009) David E. Fonseca et al.   ADVANCED DRUG DELIVERY REVIEWS

Toll-like Receptor and RIG-1-like Receptor Signaling

(2009) Taro Kawai et al.   Annals of the New York Academy of Sciences

Pharmacological Exploitation of an Off-Target Antibacterial Effect of the Cyclooxygenase-2 Inhibitor Celecoxib against Francisella tularensis

(2009) H.-C. Chiu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Eradication of Intracellular Salmonella enterica Serovar Typhimurium with a Small-Molecule, Host Cell-Directed Agent

(2009) H.-C. Chiu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The extrinsic RNA-sensing pathway for adjuvant immunotherapy of cancer

(2009) Tsukasa Seya et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Stimulation of human macrophages (THP-1) using Toll-like receptor-2 (TLR-2) agonist decorated nanocarriers

(2009) Simon Heuking et al.   JOURNAL OF DRUG TARGETING

Novel peptide therapeutics for treatment of infections

(2009) P. C. F. Oyston et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Nanoparticle-Delivered Multimeric Soluble CD40L DNA Combined with Toll-Like Receptor Agonists as a Treatment for Melanoma

(2009) Geoffrey W. Stone et al.   PLoS One

Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy

(2009) K. E. Broaders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

First-Line Therapy for Human Cutaneous Leishmaniasis in Peru Using the TLR7 Agonist Imiquimod in Combination with Pentavalent Antimony

(2009) Cesar Miranda-Verastegui et al.   PLoS Neglected Tropical Diseases

TLR3: Interferon induction by double-stranded RNA including poly(I:C)☆

(2008) M MATSUMOTO et al.   ADVANCED DRUG DELIVERY REVIEWS

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Poly(I:C) coated PLGA microparticles induce dendritic cell maturation

(2008) C WISCHKE et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Acetal-Derivatized Dextran: An Acid-Responsive Biodegradable Material for Therapeutic Applications

(2008) Eric M. Bachelder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TLR7 and TLR8 as targets in cancer therapy

(2008) M P Schön et al.   ONCOGENE

Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin

(2007) James W. Huleatt et al.   VACCINE