Multidrug-resistantPseudomonas aeruginosaandAcinetobacter baumannii: resistance mechanisms and implications for therapy

Further Identification of CTX-M-2 Extended-Spectrum  -Lactamase in Pseudomonas aeruginosa

(2009) R. C. Picao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vivo Selection of Reduced Susceptibility to Carbapenems in Acinetobacter baumannii Related to ISAba1-Mediated Overexpression of the Natural blaOXA-66 Oxacillinase Gene

(2009) S. Figueiredo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Extended-Spectrum Cephalosporinases in Pseudomonas aeruginosa

(2009) J.-M. Rodriguez-Martinez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

First Organisms with Acquired Metallo- -Lactamases (IMP-13, IMP-22, and VIM-2) Reported in Austria

(2009) W. Duljasz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Epidemiology of Outbreak-Related Pseudomonas aeruginosa Strains Carrying the Novel Variant blaVIM-17 Metallo- -Lactamase Gene

(2009) V. I. Siarkou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Involvement of pmrAB and phoPQ in Polymyxin B Adaptation and Inducible Resistance in Non-Cystic Fibrosis Clinical Isolates of Pseudomonas aeruginosa

(2009) K. N. Schurek et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Surveillance of Carbapenem-Resistant Pseudomonas aeruginosa Isolates from Puerto Rican Medical Center Hospitals: Dissemination of KPC and IMP-18  -Lactamases

(2009) D. J. Wolter et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Detection of the Novel Extended-Spectrum  -Lactamase OXA-161 from a Plasmid-Located Integron in Pseudomonas aeruginosa Clinical Isolates from Spain

(2009) C. Juan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of High-Dose, Prolonged-Infusion Cefepime in Adult Critically Ill Patients with Ventilator-Associated Pneumonia

(2009) A. M. Nicasio et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetic Analysis of Colistin Methanesulfonate and Colistin after Intravenous Administration in Critically Ill Patients with Infections Caused by Gram-Negative Bacteria

(2009) D. Plachouras et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic and Biochemical Characterization of the First Extended-Spectrum CARB-Type ss-Lactamase, RTG-4, from Acinetobacter baumannii

(2009) A. Potron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

GES-11, a Novel Integron-Associated GES Variant in Acinetobacter baumannii

(2009) C. Moubareck et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

OXA-143, a Novel Carbapenem-Hydrolyzing Class D  -Lactamase in Acinetobacter baumannii

(2009) P. G. Higgins et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance to Colistin in Acinetobacter baumannii Associated with Mutations in the PmrAB Two-Component System

(2009) M. D. Adams et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

AmpC  -Lactamases

(2009) G. A. Jacoby   CLINICAL MICROBIOLOGY REVIEWS

Clinically significant carbapenemases: an update

(2009) Timothy R Walsh   CURRENT OPINION IN INFECTIOUS DISEASES

Independent emergence of colistin-resistant Acinetobacter spp. isolates from Korea

(2009) Young Kyoung Park et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

A Long Journey from Minimum Inhibitory Concentration Testing to Clinically Predictive Breakpoints: Deterministic and Probabilistic Approaches in Deriving Breakpoints

(2009) A. Dalhoff et al.   INFECTION

Combination Antimicrobial Treatment Versus Monotherapy: The Contribution of Meta-analyses

(2009) Mical Paul et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

A review of tigecycline — the first glycylcycline

(2009) Lance R. Peterson   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Tigecycline possibly underdosed for the treatment of pneumonia: a pharmacokinetic viewpoint

(2009) Olaf Burkhardt et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Comparison of the pharmacodynamics of imipenem in patients with ventilator-associated pneumonia following administration by 2 or 0.5 h infusion

(2009) S. Jaruratanasirikul et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Influence of testing methodology on the tigecycline activity profile against presumably tigecycline-non-susceptible Acinetobacter spp.

(2009) M. Casal et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline

(2009) N. C. Gordon et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

(2009) Jason A. Roberts et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High Concentrations of Manganese in Mueller-Hinton Agar Increase MICs of Tigecycline Determined by Etest

(2009) C. Fernandez-Mazarrasa et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Stable Polymyxin B Susceptibility to Pseudomonas aeruginosa and Acinetobacter spp. despite Persistent Recovery of These Organisms from Respiratory Secretions of Patients with Ventilator-Associated Pneumonia Treated with This Drug

(2009) A. P. Zavascki et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Pharmacokinetic Considerations regarding Tigecycline for Multidrug-Resistant (MDR) Klebsiella pneumoniae or MDR Acinetobacter baumannii Urosepsis

(2009) B. A. Cunha   JOURNAL OF CLINICAL MICROBIOLOGY

Penicillin‐Binding Protein 7/8 Contributes to the Survival ofAcinetobacter baumanniiIn Vitro and In Vivo

(2009) Thomas A. Russo et al.   JOURNAL OF INFECTIOUS DISEASES

Pseudomonas aeruginosa – a phenomenon of bacterial resistance

(2009) Tanya Strateva et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Codetection of blaOXA-23-Like Gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: Report from the SENTRY Antimicrobial Surveillance Program

(2008) R. E. Mendes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Acinetobacter radioresistens as a Silent Source of Carbapenem Resistance for Acinetobacter spp.

(2008) L. Poirel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Metallo- -Lactamase Gene blaIMP-15 in a Class 1 Integron, In95, from Pseudomonas aeruginosa Clinical Isolates from a Hospital in Mexico

(2008) U. Garza-Ramos et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

KPC-2-Producing Enterobacter cloacae and Pseudomonas putida Coinfection in a Liver Transplant Recipient

(2008) J. W. Bennett et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenem Resistance among Pseudomonas aeruginosa Strains from India: Evidence for Nationwide Endemicity of Multiple Metallo- -Lactamase Clones (VIM-2, -5, -6, and -11 and the Newly Characterized VIM-18)

(2008) M. Castanheira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Timing and Dynamics of Single Cell Gene Expression in the Arabinose Utilization System

(2008) Judith A. Megerle et al.   BIOPHYSICAL JOURNAL

Outcomes of Bacteremia due to Pseudomonas aeruginosa with Reduced Susceptibility to Piperacillin-Tazobactam: Implications on the Appropriateness of the Resistance Breakpoint

(2008) V. H. Tam et al.   CLINICAL INFECTIOUS DISEASES

Increased Antimicrobial Susceptibility Profiles among Polymyxin‐ResistantAcinetobacter baumanniiClinical Isolates

(2008) Rodrigo E. Mendes et al.   CLINICAL INFECTIOUS DISEASES

Pandrug Resistance (PDR), Extensive Drug Resistance (XDR), and Multidrug Resistance (MDR) among Gram‐Negative Bacilli: Need for International Harmonization in Terminology

(2008) Matthew E. Falagas et al.   CLINICAL INFECTIOUS DISEASES

Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients

(2008) Alexandre P. Zavascki et al.   CLINICAL INFECTIOUS DISEASES

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Sulbactam-containing β-lactamase inhibitor combinations

(2008) M. Akova   CLINICAL MICROBIOLOGY AND INFECTION

Defining an extended-spectrum β-lactamase

(2008) D.M. Livermore   CLINICAL MICROBIOLOGY AND INFECTION

First identification of VIM-4 metallo-β-lactamase in Acinetobacter spp.

(2008) S. Figueiredo et al.   CLINICAL MICROBIOLOGY AND INFECTION

Dissemination of multidrug-resistant, class 1 integron-carrying Acinetobacter baumannii isolates in Taiwan

(2008) L.-Y. Huang et al.   CLINICAL MICROBIOLOGY AND INFECTION

Polymyxins Revisited

(2008) D. Landman et al.   CLINICAL MICROBIOLOGY REVIEWS

Acinetobacter baumannii: Emergence of a Successful Pathogen

(2008) A. Y. Peleg et al.   CLINICAL MICROBIOLOGY REVIEWS

Integrated results of 2 phase 3 studies comparing tigecycline and levofloxacin in community-acquired pneumonia

(2008) Cristina Tanaseanu et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Outbreak by meropenem-resistant Pseudomonas aeruginosa producing IMP-6 metallo-β-lactamase in a Korean hospital

(2008) Nam Hee Ryoo et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Safety and efficacy of intravenous tigecycline in treatment of community-acquired pneumonia: results from a double-blind randomized phase 3 comparison study with levofloxacin

(2008) Carlos Bergallo et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Establishing the role of tigecycline in an era of antimicrobial resistance

(2008) Jason J Schafer et al.   Expert Review of Anti-Infective Therapy

What is in the pipeline for Gram-negative pathogens?

(2008) George H Talbot   Expert Review of Anti-Infective Therapy

Cefepime: a reappraisal in an era of increasing antimicrobial resistance

(2008) Andrea Endimiani et al.   Expert Review of Anti-Infective Therapy

Molecular characterisation of the metallo-β-lactamase genes in imipenem-resistant Gram-negative bacteria from a university hospital in southern Taiwan

(2008) Mei-Feng Lee et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Pandrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii infections: Characteristics and outcome in a series of 28 patients

(2008) Matthew E. Falagas et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Role of outer membrane protein OprD and penicillin-binding proteins in resistance of Pseudomonas aeruginosa to imipenem and meropenem

(2008) Anna Farra et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Rational antibiotic therapy and the position of ampicillin/sulbactam

(2008) Hartmut M. Lode   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The new treatment paradigm and the role of carbapenems

(2008) Robert G. Masterton   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Nosocomial bloodstream infections due to metallo- -lactamase-producing Pseudomonas aeruginosa

(2008) A. P. Zavascki et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Susceptibility testing of tigecycline against Acinetobacter spp. by disc diffusion method: withdrawing a therapeutic option by varying the Mueller-Hinton agar?

(2008) L. F. Canigia et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Tigecycline pharmacokinetic/pharmacodynamic update

(2008) A. P. MacGowan   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A Phase 3, open-label, non-comparative study of tigecycline in the treatment of patients with selected serious infections due to resistant Gram-negative organisms including Enterobacter species, Acinetobacter baumannii and Klebsiella pneumoniae

(2008) K. Vasilev et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Tigecycline for the treatment of multidrug-resistant (including carbapenem-resistant) Acinetobacter infections: a review of the scientific evidence

(2008) D. E. Karageorgopoulos et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparison of once-, twice- and thrice-daily dosing of colistin on antibacterial effect and emergence of resistance: studies with Pseudomonas aeruginosa in an in vitro pharmacodynamic model

(2008) P. J. Bergen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Treatment of Recurrent Urosepsis with Tigecycline: a Pharmacological Perspective

(2008) D. Curcio   JOURNAL OF CLINICAL MICROBIOLOGY

Dissemination of IMP-1 and OXA Type β-Lactamase in Carbapenem-resistantAcinetobacter baumannii

(2008) Ji Youn Sung et al.   Korean Journal of Laboratory Medicine

Intravenous colistimethate for multidrug-resistant Gram-negative bacteria

(2008) Alexandre P Zavascki et al.   LANCET INFECTIOUS DISEASES

Detection of SHV-1 β-lactamase in Pseudomonas aeruginosa strains by genetic methods

(2008) S. Kalai Blagui et al.   PATHOLOGIE BIOLOGIE

First detection of the OXA-40 carbapenemase in P. aeruginosa isolates, located on a plasmid also found in A. baumannii

(2008) E. Sevillano et al.   PATHOLOGIE BIOLOGIE

First report of qnrB-producing Enterobacter cloacae and qnrA-producing Acinetobacter baumannii recovered from Algerian hospitals

(2007) Abdelaziz Touati et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Pharmacokinetics of polymyxin B1 in patients with multidrug-resistant Gram-negative bacterial infections

(2007) Andrea L.H. Kwa et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE