标题
Mitochondrion: an emerging platform critical for host antiviral signaling
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 15, Issue 5, Pages 647-665
出版商
Informa Healthcare
发表日期
2011-02-26
DOI
10.1517/14728222.2011.561321
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity
- (2010) Evelyn Dixit et al. CELL
- NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways
- (2010) Jun Cui et al. CELL
- Emerging Role of ISG15 in Antiviral Immunity
- (2010) Brian Skaug et al. CELL
- Tom70 imports antiviral immunity to the mitochondria
- (2010) Rongtuan Lin et al. CELL RESEARCH
- Tom70 mediates activation of interferon regulatory factor 3 on mitochondria
- (2010) Xin-Yi Liu et al. CELL RESEARCH
- The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling
- (2010) Rui Chen et al. CELL RESEARCH
- Hepatitis B virus X protein suppresses virus-triggered IRF3 activation and IFN-β induction by disrupting the VISA-associated complex
- (2010) Xianmiao Wang et al. Cellular & Molecular Immunology
- Viral apoptosis is induced by IRF-3-mediated activation of Bax
- (2010) Saurabh Chattopadhyay et al. EMBO JOURNAL
- DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential
- (2010) Hiroyuki Oshiumi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA
- (2010) Tetsuo Tsuchida et al. IMMUNITY
- Influenza A Virus Polymerase Inhibits Type I Interferon Induction by Binding to Interferon β Promoter Stimulator 1
- (2010) Atsushi Iwai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Virus-triggered Ubiquitination of TRAF3/6 by cIAP1/2 Is Essential for Induction of Interferon-β (IFN-β) and Cellular Antiviral Response
- (2010) Ai-Ping Mao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases
- (2010) Kislay Parvatiyar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Negative Role of RIG-I Serine 8 Phosphorylation in the Regulation of Interferon-β Production
- (2010) Estanislao Nistal-Villán et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKK and DDX3
- (2010) S. Yu et al. JOURNAL OF GENERAL VIROLOGY
- The Hepatitis B Virus X Protein Disrupts Innate Immunity by Downregulating Mitochondrial Antiviral Signaling Protein
- (2010) C. Wei et al. JOURNAL OF IMMUNOLOGY
- NLRC5 Deficiency Does Not Influence Cytokine Induction by Virus and Bacteria Infections
- (2010) H. Kumar et al. JOURNAL OF IMMUNOLOGY
- The 3C Protein of Enterovirus 71 Inhibits Retinoid Acid-Inducible Gene I-Mediated Interferon Regulatory Factor 3 Activation and Type I Interferon Responses
- (2010) X. Lei et al. JOURNAL OF VIROLOGY
- Phosphorylation-Mediated Negative Regulation of RIG-I Antiviral Activity
- (2010) M. U. Gack et al. JOURNAL OF VIROLOGY
- Positive Regulation of Interferon Regulatory Factor 3 Activation by Herc5 via ISG15 Modification
- (2010) H. X. Shi et al. MOLECULAR AND CELLULAR BIOLOGY
- IFI16 is an innate immune sensor for intracellular DNA
- (2010) Leonie Unterholzner et al. NATURE IMMUNOLOGY
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- TRAF5 Is a Downstream Target of MAVS in Antiviral Innate Immune Signaling
- (2010) Eric D. Tang et al. PLoS One
- LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
- (2010) T. Satoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The danger model in deciphering autoimmunity
- (2010) A. A. Tveita RHEUMATOLOGY
- Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1
- (2010) Kazuhide Onoguchi et al. PLoS Pathogens
- Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion
- (2010) Haifeng Wang et al. PLoS Pathogens
- Murine Gamma-Herpesvirus 68 Hijacks MAVS and IKKβ to Initiate Lytic Replication
- (2010) Xiaonan Dong et al. PLoS Pathogens
- SUMOylation of RIG-I positively regulates the type I interferon signaling
- (2010) Zhiqiang Mi et al. Protein & Cell
- RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway
- (2009) Yu-Hsin Chiu et al. CELL
- Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway
- (2009) Céline Castanier et al. EMBO REPORTS
- c-Abl tyrosine kinase interacts with MAVS and regulates innate immune response
- (2009) Ting Song et al. FEBS LETTERS
- The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA
- (2009) Bo Zhong et al. IMMUNITY
- Polo-like Kinase 1 (PLK1) Regulates Interferon (IFN) Induction by MAVS
- (2009) Damien Vitour et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Virus-triggered Signaling by OTUB1- and OTUB2-mediated Deubiquitination of TRAF3 and TRAF6
- (2009) Shu Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Tyrosine Kinase c-Src Enhances RIG-I (Retinoic Acid-inducible Gene I)-elicited Antiviral Signaling
- (2009) Ingvild B. Johnsen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Loss of Function Mutations in Human Genes Encoding RIG-I and MDA5
- (2009) Taeko Shigemoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix
- (2009) D. Arnoult et al. JOURNAL OF CELL SCIENCE
- Negative Regulation of MAVS-Mediated Innate Immune Response by PSMA7
- (2009) Y. Jia et al. JOURNAL OF IMMUNOLOGY
- TRIM21 Is Essential to Sustain IFN Regulatory Factor 3 Activation during Antiviral Response
- (2009) K. Yang et al. JOURNAL OF IMMUNOLOGY
- Human Respiratory Syncytial Virus Nonstructural Protein NS2 Antagonizes the Activation of Beta Interferon Transcription by Interacting with RIG-I
- (2009) Z. Ling et al. JOURNAL OF VIROLOGY
- MAVS Self-Association Mediates Antiviral Innate Immune Signaling
- (2009) E. D. Tang et al. JOURNAL OF VIROLOGY
- Ubiquitin-Regulated Recruitment of I B Kinase to the MAVS Interferon Signaling Adapter
- (2009) S. Paz et al. MOLECULAR AND CELLULAR BIOLOGY
- Key Role of Ubc5 and Lysine-63 Polyubiquitination in Viral Activation of IRF3
- (2009) Wenwen Zeng et al. MOLECULAR CELL
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate
- (2009) Andrea Ablasser et al. NATURE IMMUNOLOGY
- PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4
- (2009) Fuping You et al. NATURE IMMUNOLOGY
- An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
- (2009) Tilmann Bürckstümmer et al. NATURE IMMUNOLOGY
- MAVS-Mediated Apoptosis and Its Inhibition by Viral Proteins
- (2009) Yu Lei et al. PLoS One
- REUL Is a Novel E3 Ubiquitin Ligase and Stimulator of Retinoic-Acid-Inducible Gene-I
- (2009) Dong Gao et al. PLoS One
- Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
- (2009) T. Saitoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF- B activation
- (2009) Y.-Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response
- (2009) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
- (2009) W. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA
- (2009) T. L. Roberts et al. SCIENCE
- Mitofusin 2 Inhibits Mitochondrial Antiviral Signaling
- (2009) K. Yasukawa et al. Science Signaling
- The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation
- (2009) Peyman Nakhaei et al. PLoS Pathogens
- The Hsp90 molecular chaperone: an open and shut case for treatment
- (2008) Laurence H. Pearl et al. BIOCHEMICAL JOURNAL
- Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
- (2008) Daniel B. Stetson et al. CELL
- The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases
- (2008) M Rebsamen et al. CELL DEATH AND DIFFERENTIATION
- MDA5/RIG-I and virus recognition
- (2008) Osamu Takeuchi et al. CURRENT OPINION IN IMMUNOLOGY
- NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production
- (2008) Ivan Tattoli et al. EMBO REPORTS
- The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response
- (2008) Constantin S Friedman et al. EMBO REPORTS
- Structural Mechanism of RNA Recognition by the RIG-I-like Receptors
- (2008) Mitsutoshi Yoneyama et al. IMMUNITY
- Regulation of Mitochondrial Antiviral Signaling Pathways
- (2008) Chris B. Moore et al. IMMUNITY
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- Virus Infection Triggers SUMOylation of IRF3 and IRF7, Leading to the Negative Regulation of Type I Interferon Gene Expression
- (2008) Toru Kubota et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of IκB Kinase-related Kinases and Antiviral Responses by Tumor Suppressor CYLD
- (2008) Minying Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Riplet/RNF135, a RING Finger Protein, Ubiquitinates RIG-I to Promote Interferon-β Induction during the Early Phase of Viral Infection
- (2008) Hiroyuki Oshiumi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MAVS Dimer Is a Crucial Signaling Component of Innate Immunity and the Target of Hepatitis C Virus NS3/4A Protease
- (2008) M. Baril et al. JOURNAL OF VIROLOGY
- NLRX1 is a regulator of mitochondrial antiviral immunity
- (2008) Chris B. Moore et al. NATURE
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
- Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction
- (2008) M. U. Gack et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- UbcH8 regulates ubiquitin and ISG15 conjugation to RIG-I
- (2007) Kei-Ichiro Arimoto et al. MOLECULAR IMMUNOLOGY
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