标题
Cell- and biomarker-based assays for predicting nephrotoxicity
作者
关键词
-
出版物
Expert Opinion on Drug Metabolism & Toxicology
Volume 10, Issue 12, Pages 1621-1635
出版商
Informa Healthcare
发表日期
2014-11-11
DOI
10.1517/17425255.2014.967681
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Critical analysis of 3-D organoid in vitro cell culture models for high-throughput drug candidate toxicity assessments
- (2014) Anna Astashkina et al. ADVANCED DRUG DELIVERY REVIEWS
- MicroRNA profiling of rats with ochratoxin A nephrotoxicity
- (2014) Qiu Dai et al. BMC GENOMICS
- Solute carrier transporter and drug-related nephrotoxicity: the impact of proximal tubule cell models for preclinical research
- (2014) Pascale Fisel et al. Expert Opinion on Drug Metabolism & Toxicology
- Drug-Induced Nephrotoxicity: Clinical Impact and Preclinical in Vitro Models
- (2014) Ho Yee Tiong et al. MOLECULAR PHARMACEUTICS
- Microfluidic organs-on-chips
- (2014) Sangeeta N Bhatia et al. NATURE BIOTECHNOLOGY
- 3D bioprinting of tissues and organs
- (2014) Sean V Murphy et al. NATURE BIOTECHNOLOGY
- Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
- (2014) David Cook et al. NATURE REVIEWS DRUG DISCOVERY
- Acute kidney injury—epidemiology, outcomes and economics
- (2014) Oleksa Rewa et al. Nature Reviews Nephrology
- The current status of biomarkers for predicting toxicity
- (2013) Sarah Campion et al. Expert Opinion on Drug Metabolism & Toxicology
- Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
- (2013) Kyung-Jin Jang et al. Integrative Biology
- Analysis of a Urinary Biomarker Panel for Incident Kidney Disease and Clinical Outcomes
- (2013) C. M. O'Seaghdha et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Neutrophil gelatinase-associated lipocalin, a sensitive urinary biomarker of acute kidney injury in dogs receiving gentamicin
- (2013) Kiyonori Kai et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine
- (2013) Lesley Cheng et al. KIDNEY INTERNATIONAL
- MicroRNAs in kidney diseases: new promising biomarkers for diagnosis and monitoring
- (2013) F. P. Schena et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Cystatin C versus Creatinine in Determining Risk Based on Kidney Function
- (2013) Michael G. Shlipak et al. NEW ENGLAND JOURNAL OF MEDICINE
- Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity
- (2013) Teresa M. DesRochers et al. PLoS One
- Early Prediction of Polymyxin-Induced Nephrotoxicity With Next-Generation Urinary Kidney Injury Biomarkers
- (2013) Natalie D. Keirstead et al. TOXICOLOGICAL SCIENCES
- In vitro evaluation of biomarkers for cisplatin-induced nephrotoxicity using HK-2 human kidney epithelial cells
- (2013) So-Jung Sohn et al. TOXICOLOGY LETTERS
- An in vitro method for the prediction of renal proximal tubular toxicity in humans
- (2013) Yao Li et al. Toxicology Research
- Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines
- (2012) Anna I. Astashkina et al. BIOMATERIALS
- A 3-D organoid kidney culture model engineered for high-throughput nephrotoxicity assays
- (2012) Anna I. Astashkina et al. BIOMATERIALS
- Detection and management of nephrotoxicity during drug development
- (2012) Dr Mahmoud Loghman-Adham et al. Expert Opinion On Drug Safety
- Assay Validation for KIM-1: human urinary renal dysfunction biomarker
- (2012) Shalini Chaturvedi et al. International Journal of Biological Sciences
- MicroRNA-494 Reduces ATF3 Expression and Promotes AKI
- (2012) Y.-F. Lan et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Temporal Changes in Incidence of Dialysis-Requiring AKI
- (2012) R. K. Hsu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule
- (2012) Sarah E. Jenkinson et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes
- (2012) Alessia Gallo et al. PLoS One
- Expression, Circulation, and Excretion Profile of MicroRNA-21, -155, and -18a Following Acute Kidney Injury
- (2012) Janani Saikumar et al. TOXICOLOGICAL SCIENCES
- Biomarkers for Drug-Induced Renal Damage and Nephrotoxicity—An Overview for Applied Toxicology
- (2011) Tobias Christian Fuchs et al. AAPS Journal
- Colony-Stimulating Factor-1 Promotes Kidney Growth and Repair via Alteration of Macrophage Responses
- (2011) Maliha A. Alikhan et al. AMERICAN JOURNAL OF PATHOLOGY
- Serum Clusterin Levels Are Not Increased in Presymptomatic Alzheimer’s Disease
- (2011) Linda IJsselstijn et al. JOURNAL OF PROTEOME RESEARCH
- Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis
- (2011) X. Zhong et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Biomarkers in chronic kidney disease: a review
- (2011) Robert G. Fassett et al. KIDNEY INTERNATIONAL
- Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury
- (2011) Ion D. Bucaloiu et al. KIDNEY INTERNATIONAL
- Induction of lipocalin-2 expression in acute and chronic experimental liver injury moderated by pro-inflammatory cytokines interleukin-1β through nuclear factor-κB activation
- (2011) Erawan Borkham-Kamphorst et al. LIVER INTERNATIONAL
- The Ngal reporter mouse detects the response of the kidney to injury in real time
- (2011) Neal Paragas et al. NATURE MEDICINE
- Evaluation of Drugs With Specific Organ Toxicities in Organ-Specific Cell Lines
- (2011) Zhiwu Lin et al. TOXICOLOGICAL SCIENCES
- The beautiful cell: high-content screening in drug discovery
- (2010) Marc Bickle ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Comparison of the novel HK-2 human renal proximal tubular cell line with the standard LLC-PK1 cell line in studying drug-induced nephrotoxicity
- (2010) Patrina Gunness et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Role of hERG potassium channel assays in drug development
- (2010) Birgit Priest et al. Channels
- Increased serum levels of macrophage colony-stimulating factor (M-CSF) in α-and β-thalassaemia syndromes: correlation with anaemia and monocyte activation
- (2010) Edith Wiener et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Lipocalin 2 is essential for chronic kidney disease progression in mice and humans
- (2010) Amandine Viau et al. JOURNAL OF CLINICAL INVESTIGATION
- Metabolic response to low-level toxicant exposure in a novel renal tubuleepithelial cell system
- (2010) James Keith Ellis et al. Molecular BioSystems
- Unknown
- (2010) Kirti Bhatt et al. MOLECULAR MEDICINE
- Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury
- (2010) Yan Yu et al. NATURE BIOTECHNOLOGY
- Urinary clusterin, cystatin C, β2-microglobulin and total protein as markers to detect drug-induced kidney injury
- (2010) Frank Dieterle et al. NATURE BIOTECHNOLOGY
- Next-generation biomarkers for detecting kidney toxicity
- (2010) Joseph V Bonventre et al. NATURE BIOTECHNOLOGY
- Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium
- (2010) Frank Dieterle et al. NATURE BIOTECHNOLOGY
- Towards consensus practices to qualify safety biomarkers for use in early drug development
- (2010) Frank D Sistare et al. NATURE BIOTECHNOLOGY
- A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function
- (2010) Josef S Ozer et al. NATURE BIOTECHNOLOGY
- Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies
- (2010) Vishal S Vaidya et al. NATURE BIOTECHNOLOGY
- Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of cyclosporine nephrotoxicity?
- (2010) Anna Wasilewska et al. PEDIATRIC NEPHROLOGY
- Evaluation of a urinary kidney biomarker panel in rat models of acute and subchronic nephrotoxicity
- (2010) Dana Hoffmann et al. TOXICOLOGY
- Intrarenal Expression of miRNAs in Patients With Hypertensive Nephrosclerosis
- (2009) G. Wang et al. AMERICAN JOURNAL OF HYPERTENSION
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Progression of Chronic Kidney Disease
- (2009) D. Bolignano et al. Clinical Journal of the American Society of Nephrology
- Applications of High Content Screening in Life Science Research
- (2009) Joseph Zock COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
- Tissue-specific, non-invasive toxicity biomarkers: translation from preclinical safety assessment to clinical safety monitoring
- (2009) Patrick Y Muller et al. Expert Opinion on Drug Metabolism & Toxicology
- CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice
- (2009) Julia Menke et al. JOURNAL OF CLINICAL INVESTIGATION
- A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells
- (2009) Kyung-Jin Jang et al. LAB ON A CHIP
- Persistent Elevation of Plasma Osteopontin Levels in HIV Patients Despite Highly Active Antiretroviral Therapy
- (2009) Haorile Chagan-Yasutan et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Multiplexed assay panel of cytotoxicity in HK-2 cells for detection of renal proximal tubule injury potential of compounds
- (2009) Yang Wu et al. TOXICOLOGY IN VITRO
- The interaction of hepatitis A virus (HAV) with soluble forms of its cellular receptor 1 (HAVCR1) share the physiological requirements of infectivity in cell culture
- (2009) Erica Silberstein et al. Virology Journal
- 3D cell culture opens new dimensions in cell-based assays
- (2008) Bradley A. Justice et al. DRUG DISCOVERY TODAY
- Genistein protects the kidney from cisplatin-induced injury
- (2008) Mi Jeong Sung et al. KIDNEY INTERNATIONAL
- Neutrophil gelatinase‐associated lipocalin (NGAL): A new marker of kidney disease
- (2008) Peasad Devarajan SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
- Biomarkers of Acute Kidney Injury
- (2007) Vishal S. Vaidya et al. Annual Review of Pharmacology and Toxicology
- Urinary biomarkers in the early diagnosis of acute kidney injury
- (2007) W.K. Han et al. KIDNEY INTERNATIONAL
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started