An in vitro method for the prediction of renal proximal tubular toxicity in humans

Human embryonic stem cells differentiate into functional renal proximal tubular–like cells

(2013) Karthikeyan Narayanan et al.   KIDNEY INTERNATIONAL

Comparing predictive drug nephrotoxicity biomarkers in kidney 3-D primary organoid culture and immortalized cell lines

(2012) Anna I. Astashkina et al.   BIOMATERIALS

A 3-D organoid kidney culture model engineered for high-throughput nephrotoxicity assays

(2012) Anna I. Astashkina et al.   BIOMATERIALS

Interleukin-6 and interleukin-8 levels in the urine of children with renal scarring

(2012) Despoina Tramma et al.   PEDIATRIC NEPHROLOGY

The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule

(2012) Sarah E. Jenkinson et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The use of a library of industrial materials to determine the nature of substrate-dependent performance of primary adherent human cells

(2011) Ming Ni et al.   BIOMATERIALS

Acute Kidney Injury and Increasing Nephrotoxic-Medication Exposure in Noncritically-Ill Children

(2011) B. S. Moffett et al.   Clinical Journal of the American Society of Nephrology

Earlier recognition of nephrotoxicity using novel biomarkers of acute kidney injury

(2011) W. Stephen Waring et al.   CLINICAL TOXICOLOGY

Effects of quantum dots on different renal proximal tubule cell models and on gel-free renal tubules generatedin vitro

(2011) Yao Li et al.   Nanotoxicology

Effects of Bone Morphogenetic Proteins on Primary Human Renal Cells and the Generation of Bone Morphogenetic Protein-7-Expressing Cells for Application in Bioartificial Kidneys

(2011) Farah Tasnim et al.   TISSUE ENGINEERING PART A

Evaluation of Drugs With Specific Organ Toxicities in Organ-Specific Cell Lines

(2011) Zhiwu Lin et al.   TOXICOLOGICAL SCIENCES

Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes

(2011) Alice Limonciel et al.   TOXICOLOGY IN VITRO

A high-throughput respirometric assay for mitochondrial biogenesis and toxicity

(2010) Craig C. Beeson et al.   ANALYTICAL BIOCHEMISTRY

Characterization of membrane materials and membrane coatings for bioreactor units of bioartificial kidneys

(2010) Ming Ni et al.   BIOMATERIALS

Mediators of Inflammation in Acute Kidney Injury

(2010) Ali Akcay et al.   MEDIATORS OF INFLAMMATION

Next-generation biomarkers for detecting kidney toxicity

(2010) Joseph V Bonventre et al.   NATURE BIOTECHNOLOGY

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

(2010) Frank Dieterle et al.   NATURE BIOTECHNOLOGY

Secreted proteins from adipose tissue and skeletal muscle – adipokines, myokines and adipose/muscle cross-talk

(2010) Paul Trayhurn et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

The nephrotoxic effects of HAART

(2009) Hassane Izzedine et al.   Nature Reviews Nephrology

Upregulated IL-18 expression in type 2 diabetic subjects with nephropathy: TGF-β1 enhanced IL-18 expression in human renal proximal tubular epithelial cells

(2008) Kazunari Miyauchi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The Local and Systemic Inflammatory Transcriptome after Acute Kidney Injury

(2008) D. N. Grigoryev et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cell models for studying renal physiology

(2008) M. Bens et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY