Studying ongoing and spontaneous pain in rodents - challenges and opportunities

Validation and implementation of a novel high-throughput behavioral phenotyping instrument for mice

(2014) Jesse Brodkin et al.   JOURNAL OF NEUROSCIENCE METHODS

Alleviation of chronic neuropathic pain by environmental enrichment in mice well after the establishment of chronic pain

(2013) Pascal Vachon et al.   Behavioral and Brain Functions

Burrowing as a non-reflex behavioural readout for analgesic action in a rat model of sub-chronic knee joint inflammation

(2013) K. Rutten et al.   EUROPEAN JOURNAL OF PAIN

Brain-network mechanisms underlying the divergent effects of depression on spontaneous versus evoked pain in rats: A multiple single-unit study

(2013) Ning Wang et al.   EXPERIMENTAL NEUROLOGY

Rotterdam Advanced Multiple Plate: A novel method to measure cold hyperalgesia and allodynia in freely behaving rodents

(2013) Liron S. Duraku et al.   JOURNAL OF NEUROSCIENCE METHODS

Suppression of Voluntary Wheel Running in Rats Is Dependent on the Site of Inflammation: Evidence for Voluntary Running as a Measure of Hind Paw-Evoked Pain

(2013) Peter M. Grace et al.   JOURNAL OF PAIN

Voluntary Movements as a Possible Non-Reflexive Pain Assay

(2013) Hawon Cho et al.   Molecular Pain

A back translation of pregabalin and carbamazepine against evoked and non-evoked endpoints in the rat spared nerve injury model of neuropathic pain

(2013) W. Lau et al.   NEUROPHARMACOLOGY

Assessment of avoidance behaviors in mouse models of muscle pain

(2013) D. Pratt et al.   NEUROSCIENCE

Social stress exacerbates the aversion to painful experiences in rats exposed to chronic pain: The role of the locus coeruleus

(2013) Lidia Bravo et al.   PAIN

A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy

(2013) Wenlong Huang et al.   PAIN

Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain

(2012) Alexandre J. Parent et al.   BEHAVIOURAL BRAIN RESEARCH

Spontaneous pain in partial nerve injury models of neuropathy and the role of nociceptive sensory cover

(2012) Pini Koplovitch et al.   EXPERIMENTAL NEUROLOGY

Negative Reinforcement Reveals Non-Evoked Ongoing Pain in Mice With Tissue or Nerve Injury

(2012) Ying He et al.   JOURNAL OF PAIN

Use of dynamic weight bearing as a novel end-point for the assessment of Freund's Complete Adjuvant induced hypersensitivity in mice

(2012) Ian Robinson et al.   NEUROSCIENCE LETTERS

Periaqueductal gray stimulation suppresses spontaneous pain behavior in rats

(2012) Kuo-Sheng Lee et al.   NEUROSCIENCE LETTERS

Inflammation-induced decrease in voluntary wheel running in mice: A nonreflexive test for evaluating inflammatory pain and analgesia

(2012) Enrique J. Cobos et al.   PAIN

Afferent drive elicits ongoing pain in a model of advanced osteoarthritis

(2012) Alec Okun et al.   PAIN

The Assessment of Post-Vasectomy Pain in Mice Using Behaviour and the Mouse Grimace Scale

(2012) Matthew C. Leach et al.   PLoS One

Gait Analysis in Rats with Single Joint Inflammation: Influence of Experimental Factors

(2012) Kristina Ängeby Möller et al.   PLoS One

Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry

(2012) E. Navratilova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predictive validity of behavioural animal models for chronic pain

(2011) Odd-Geir Berge   BRITISH JOURNAL OF PHARMACOLOGY

Spontaneous burrowing behaviour in the rat is reduced by peripheral nerve injury or inflammation associated pain

(2011) N. Andrews et al.   EUROPEAN JOURNAL OF PAIN

Homer1a Signaling in the Amygdala Counteracts Pain-Related Synaptic Plasticity, mGluR1 Function and Pain Behaviors

(2011) Anke Tappe-Theodor et al.   Molecular Pain

The Rat Grimace Scale: A Partially Automated Method for Quantifying Pain in the Laboratory Rat via Facial Expressions

(2011) Susana G Sotocina et al.   Molecular Pain

Ongoing pain in the MIA model of osteoarthritis

(2011) Ping Liu et al.   NEUROSCIENCE LETTERS

Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity

(2011) Tamara King et al.   PAIN

Lesion of the rostral anterior cingulate cortex eliminates the aversiveness of spontaneous neuropathic pain following partial or complete axotomy

(2011) Chaoling Qu et al.   PAIN

Behavioral indices of ongoing pain are largely unchanged in male mice with tissue or nerve injury-induced mechanical hypersensitivity

(2011) Rochelle Urban et al.   PAIN

Weight bearing evaluation in inflammatory, neuropathic and cancer chronic pain in freely moving rats

(2011) Pascal Tétreault et al.   PHYSIOLOGY & BEHAVIOR

Nav1.9 Channel Contributes to Mechanical and Heat Pain Hypersensitivity Induced by Subacute and Chronic Inflammation

(2011) Stéphane Lolignier et al.   PLoS One

Pregabalin attenuates place escape/avoidance behavior in a rat model of spinal cord injury

(2010) Cathrine Baastrup et al.   BRAIN RESEARCH

TRPV1-lineage neurons are required for thermal sensation

(2010) Santosh K Mishra et al.   EMBO JOURNAL

Depression Shows Divergent Effects on Evoked and Spontaneous Pain Behaviors in Rats

(2010) Miao Shi et al.   JOURNAL OF PAIN

An Improved Behavioural Assay Demonstrates That Ultrasound Vocalizations Constitute a Reliable Indicator of Chronic Cancer Pain and Neuropathic Pain

(2010) Martina Kurejova et al.   Molecular Pain

Hypolocomotion, Asymmetrically Directed Behaviors (Licking, Lifting, Flinching, and Shaking) and Dynamic Weight Bearing (Gait) Changes are Not Measures of Neuropathic Pain in Mice

(2010) Jeffrey S Mogil et al.   Molecular Pain

Coding of facial expressions of pain in the laboratory mouse

(2010) Dale J Langford et al.   NATURE METHODS

Spinal-, brainstem- and cerebrally mediated responses at- and below-level of a spinal cord contusion in rats: Evaluation of pain-like behavior

(2010) Cathrine Baastrup et al.   PAIN

Monosodium iodoacetate-induced osteoarthritis produces pain-depressed wheel running in rats: Implications for preclinical behavioral assessment of chronic pain

(2010) Glenn W. Stevenson et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Burrowing Behavior as an Indicator of Post-Laparotomy Pain in Mice

(2010) Paulin Jirkof et al.   Frontiers in Behavioral Neuroscience

Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models

(2009) Michael J. Piesla et al.   BRAIN RESEARCH

The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception

(2009) Jacques Noël et al.   EMBO JOURNAL

Unmasking the tonic-aversive state in neuropathic pain

(2009) Tamara King et al.   NATURE NEUROSCIENCE

Animal models of pain: progress and challenges

(2009) Jeffrey S. Mogil   NATURE REVIEWS NEUROSCIENCE

Comparison of mechanical allodynia and the affective component of inflammatory pain in rats

(2009) Janel M. Boyce-Rustay et al.   NEUROPHARMACOLOGY

Assessment of Movement-Evoked Pain in Osteoarthritis by the Knee-Bend and CatWalk Tests: A Clinically Relevant Study

(2008) Joana Ferreira-Gomes et al.   JOURNAL OF PAIN

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

(2008) Yasuhiko Kawasaki et al.   NATURE MEDICINE

A robust automated system elucidates mouse home cage behavioral structure

(2008) E. H. Goulding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA