Canonical microRNAs in thymic epithelial cells promote central tolerance

An evolutionarily conserved mutual interdependence between Aire and microRNAs in promiscuous gene expression

(2013) Olga Ucar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MicroRNA regulation of T-cell differentiation and function

(2013) Lukas T. Jeker et al.   IMMUNOLOGICAL REVIEWS

The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression

(2013) Dirk Baumjohann et al.   NATURE IMMUNOLOGY

DGCR8-Mediated Production of Canonical Micrornas Is Critical for Regulatory T Cell Function and Stability

(2013) Lukas T. Jeker et al.   PLoS One

MicroRNAs Control the Maintenance of Thymic Epithelia and Their Competence for T Lineage Commitment and Thymocyte Selection

(2012) S. Zuklys et al.   JOURNAL OF IMMUNOLOGY

Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection

(2012) R. T. Taniguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of T-cell tolerance

(2011) Roza I. Nurieva et al.   IMMUNOLOGICAL REVIEWS

Control of central and peripheral tolerance by Aire

(2011) Todd C. Metzger et al.   IMMUNOLOGICAL REVIEWS

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

(2011) Aikaterini S Papadopoulou et al.   NATURE IMMUNOLOGY

A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing

(2011) J. E. Babiarz et al.   RNA

MicroRNA Function Is Globally Suppressed in Mouse Oocytes and Early Embryos

(2010) Nayoung Suh et al.   CURRENT BIOLOGY

Small RNA Regulators of T Cell-Mediated Autoimmunity

(2010) Lukas T. Jeker et al.   JOURNAL OF CLINICAL IMMUNOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Loss of Cardiac microRNA-Mediated Regulation Leads to Dilated Cardiomyopathy and Heart Failure

(2009) Prakash K. Rao et al.   CIRCULATION RESEARCH

Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity

(2009) Mireia Guerau-de-Arellano et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tracking epitope-specific T cells

(2009) James J Moon et al.   Nature Protocols

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of an Autoantigen Demonstrates a Link Between Interstitial Lung Disease and a Defect in Central Tolerance

(2009) A. K. Shum et al.   Science Translational Medicine

Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells

(2008) L. T. Jeker et al.   BLOOD

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

(2008) J. E. Babiarz et al.   GENES & DEVELOPMENT

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

(2008) Xuyu Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

(2008) J. M. Gardner et al.   SCIENCE