MECHANISMS IN ENDOCRINOLOGY: Biological role, clinical significance, and therapeutic possibilities of the recently discovered metabolic hormone fibroblastic growth factor 21
出版年份 2012 全文链接
标题
MECHANISMS IN ENDOCRINOLOGY: Biological role, clinical significance, and therapeutic possibilities of the recently discovered metabolic hormone fibroblastic growth factor 21
作者
关键词
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出版物
EUROPEAN JOURNAL OF ENDOCRINOLOGY
Volume 167, Issue 3, Pages 301-309
出版商
Bioscientifica
发表日期
2012-06-28
DOI
10.1530/eje-12-0357
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Serum fibroblast growth factor 21 was elevated in subjects with type 2 diabetes mellitus and was associated with the presence of carotid artery plaques
- (2012) So-Yeon An et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- FGF21 regulates PGC-1 and browning of white adipose tissues in adaptive thermogenesis
- (2012) f. M. Fisher et al. GENES & DEVELOPMENT
- Relationship of Serum Fibroblast Growth Factor 21 with Abnormal Glucose Metabolism and Insulin Resistance: The Baltimore Longitudinal Study of Aging
- (2012) Richard D. Semba et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Fibroblast Growth Factor 21 (FGF-21) and Its Relation to Obesity, Metabolic Syndrome, and Nonalcoholic Fatty Liver in Children: A Longitudinal Analysis
- (2012) Thomas Reinehr et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Serum Fibroblast Growth Factor 21 Is Associated with Renal Function and Chronic Kidney Disease in Community-Dwelling Adults
- (2012) Candace Crasto et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Various Oscillation Patterns of Serum Fibroblast Growth Factor 21 Concentrations in Healthy Volunteers
- (2012) Sang Ah Lee et al. Diabetes & Metabolism Journal
- Circadian Rhythm of Circulating Fibroblast Growth Factor 21 Is Related to Diurnal Changes in Fatty Acids in Humans
- (2011) H. Yu et al. CLINICAL CHEMISTRY
- Plasma FGF21 displays a circadian rhythm during a 72-h fast in healthy female volunteers
- (2011) Birgitte Andersen et al. CLINICAL ENDOCRINOLOGY
- Fibroblast growth factor 21: effects on carbohydrate and lipid metabolism in health and disease
- (2011) Susan Kralisch et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Mitiglinide treatment may decreases plasma fibroblast growth factor-21 levels in individuals with new-onset T2DM
- (2011) Bo Wang et al. CYTOKINE
- FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in Rodents
- (2011) J. Mu et al. DIABETES
- Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity
- (2011) Fredirick L. Mashili et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Exenatide decreases hepatic fibroblast growth factor 21 resistance in non-alcoholic fatty liver disease in a mouse model of obesity and in a randomised controlled trial
- (2011) S. L. Samson et al. DIABETOLOGIA
- Serum FGF-21 Levels in Type 2 Diabetic Patients
- (2011) Xingbo Cheng et al. ENDOCRINE RESEARCH
- Growth Hormone Stimulates Transcription of the Fibroblast Growth Factor 21 Gene in the Liver through the Signal Transducer and Activator of Transcription 5
- (2011) Jie Yu et al. ENDOCRINOLOGY
- Lack of Overt FGF21 Resistance in Two Mouse Models of Obesity and Insulin Resistance
- (2011) Clarence Hale et al. ENDOCRINOLOGY
- Growth Hormone Induces Hepatic Production of Fibroblast Growth Factor 21 through a Mechanism Dependent on Lipolysis in Adipocytes
- (2011) Wei Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fibroblast Growth Factor 21 Induces Glucose Transporter-1 Expression through Activation of the Serum Response Factor/Ets-Like Protein-1 in Adipocytes
- (2011) Xuan Ge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinct Changes in Serum Fibroblast Growth Factor 21 Levels in Different Subtypes of Diabetes
- (2011) Yang Xiao et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Association between serum fibroblast growth factor 21 and diabetic nephropathy
- (2011) Wei-Xia Jian et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The effects of fibroblast growth factor-21 knockdown and over-expression on its signaling pathway and glucose–lipid metabolism in vitro
- (2011) Ke Li et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- A Better Anti-Diabetic Recombinant Human Fibroblast Growth Factor 21 (rhFGF21) Modified with Polyethylene Glycol
- (2011) Zhifeng Huang et al. PLoS One
- Circulating FGF21 Levels Are Progressively Increased from the Early to End Stages of Chronic Kidney Diseases and Are Associated with Renal Function in Chinese
- (2011) Zhuofeng Lin et al. PLoS One
- Paradoxical Regulation of Human FGF21 by Both Fasting and Feeding Signals: Is FGF21 a Nutritional Adaptation Factor?
- (2011) Takashi Uebanso et al. PLoS One
- Circulating Fibroblast Growth Factor 21 Levels Are Closely Associated with Hepatic Fat Content: A Cross-Sectional Study
- (2011) Hongmei Yan et al. PLoS One
- Effects of Short-Term Continuous Subcutaneous Insulin Infusion on Fasting Plasma Fibroblast Growth Factor-21 Levels in Patients with Newly Diagnosed Type 2 Diabetes Mellitus
- (2011) Mengliu Yang et al. PLoS One
- Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1
- (2011) A.-L. Wu et al. Science Translational Medicine
- Effects of postbariatric surgery weight loss on adipokines and metabolic parameters: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy—a prospective randomized trial
- (2011) Bettina Woelnerhanssen et al. Surgery for Obesity and Related Diseases
- Physiological modulation of circulating FGF21: relevance of free fatty acids and insulin
- (2010) Knut Mai et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARα and FGF21 transcripts in vivo
- (2010) Eric D. Berglund et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Hepatic FGF21 Expression Is Induced at Birth via PPARα in Response to Milk Intake and Contributes to Thermogenic Activation of Neonatal Brown Fat
- (2010) Elayne Hondares et al. Cell Metabolism
- Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats
- (2010) D. A. Sarruf et al. DIABETES
- Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
- (2010) f. M. Fisher et al. DIABETES
- Increased serum FGF21 levels in patients with nonalcoholic fatty liver disease
- (2010) Yusuf Yilmaz et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease
- (2010) Jody Dushay et al. GASTROENTEROLOGY
- Serum fibroblast growth factor 21 levels in polycystic ovary syndrome
- (2010) Suheyla Gorar et al. GYNECOLOGICAL ENDOCRINOLOGY
- Liver Fat But Not Other Adiposity Measures Influence Circulating FGF21 Levels in Healthy Young Adult Twins
- (2010) Henna Tyynismaa et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride
- (2010) Huating Li et al. JOURNAL OF HEPATOLOGY
- Serum fibroblast growth factor–21 concentration is associated with residual renal function and insulin resistance in end-stage renal disease patients receiving long-term peritoneal dialysis
- (2010) Seung Hyeok Han et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Relation between fibroblast growth factor–21, adiposity, metabolism, and weight reduction
- (2010) Knut Mai et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Serum Levels of FGF-21 Are Increased in Coronary Heart Disease Patients and Are Independently Associated with Adverse Lipid Profile
- (2010) Zhuofeng Lin et al. PLoS One
- Fibroblast Growth Factor-21 as a Therapeutic Agent for Metabolic Diseases
- (2009) Alexei Kharitonenkov et al. BIODRUGS
- Endocrine fibroblast growth factors as regulators of metabolic homeostasis
- (2009) Hiroshi Kurosu et al. BIOFACTORS
- Free Fatty Acids Link Metabolism and Regulation of the Insulin-Sensitizing Fibroblast Growth Factor-21
- (2009) K. Mai et al. DIABETES
- Fibroblast Growth Factor-21 Is Induced in Human Skeletal Muscles by Hyperinsulinemia
- (2009) Pernille Hojman et al. DIABETES
- Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance
- (2009) A. O. Chavez et al. DIABETES CARE
- Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity
- (2009) Eric D. Berglund et al. ENDOCRINOLOGY
- Fibroblast Growth Factor 21 Regulates Lipolysis in White Adipose Tissue But Is Not Required for Ketogenesis and Triglyceride Clearance in Liver
- (2009) Yuhei Hotta et al. ENDOCRINOLOGY
- Effects of rosiglitazone on fasting plasma fibroblast growth factor-21 levels in patients with type 2 diabetes mellitus
- (2009) Ke Li et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 inob/obmice
- (2009) Xiaofan Li et al. FEBS LETTERS
- Fibroblast Growth Factor 21 Reduces the Severity of Cerulein-Induced Pancreatitis in Mice
- (2009) Charis L. Johnson et al. GASTROENTEROLOGY
- Molecular pathology of the fibroblast growth factor family
- (2009) Pavel Krejci et al. HUMAN MUTATION
- Serum fibroblast growth factor 21 levels in gestational diabetes mellitus in relation to insulin resistance and dyslipidemia
- (2009) Sebastian Stein et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The FGF family: biology, pathophysiology and therapy
- (2009) Andrew Beenken et al. NATURE REVIEWS DRUG DISCOVERY
- The Circulating Metabolic Regulator FGF21 Is Induced by Prolonged Fasting and PPARα Activation in Man
- (2008) Cecilia Gälman et al. Cell Metabolism
- Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity
- (2008) M. Mraz et al. CLINICAL ENDOCRINOLOGY
- Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans
- (2008) X. Zhang et al. DIABETES
- Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
- (2008) J. Xu et al. DIABETES
- Serum Levels of the Adipokine FGF21 Depend on Renal Function
- (2008) S. Stein et al. DIABETES CARE
- Plasma FGF-21 levels in type 2 diabetic patients with ketosis
- (2008) Ling Li et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Fibroblast Growth Factor 21 Corrects Obesity in Mice
- (2008) Tamer Coskun et al. ENDOCRINOLOGY
- FGF21 attenuates lipolysis in human adipocytes - A possible link to improved insulin sensitivity
- (2008) Peter Arner et al. FEBS LETTERS
- Plasma Concentrations of Fibroblast Growth Factors 19 and 21 in Patients with Anorexia Nervosa
- (2008) Ivana Dostálová et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The Klotho gene family as a regulator of endocrine fibroblast growth factors
- (2008) Hiroshi Kurosu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- βKlotho Is Required for Fibroblast Growth Factor (FGF) 21 Signaling through FGF Receptor (FGFR) 1c and FGFR3c
- (2008) Masashi Suzuki et al. MOLECULAR ENDOCRINOLOGY
- Adipose Fibroblast Growth Factor 21 Is Up-Regulated by Peroxisome Proliferator-Activated Receptor and Altered Metabolic States
- (2008) E. S. Muise et al. MOLECULAR PHARMACOLOGY
- Endocrine FGFs and Klothos: emerging concepts
- (2008) Makoto Kuro-o TRENDS IN ENDOCRINOLOGY AND METABOLISM
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