Group I and II mammalian PAKs have different modes of activation by Cdc42

The emerging importance of group II PAKs

(2010) Claire M. Wells et al.   BIOCHEMICAL JOURNAL

Copy number alterations in pancreatic cancer identify recurrentPAK4amplification

(2010) Shuaili Chen et al.   CANCER BIOLOGY & THERAPY

Integrin-mediated Cell Attachment Induces a PAK4-dependent Feedback Loop Regulating Cell Adhesion through Modified Integrin αvβ5 Clustering and Turnover

(2010) Zhilun Li et al.   MOLECULAR BIOLOGY OF THE CELL

Cdc42 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells through PAK4 and Par6B

(2010) Sean W. Wallace et al.   MOLECULAR BIOLOGY OF THE CELL

A Functional Requirement for PAK1 Binding to the KH(2) Domain of the Fragile X Protein-Related FXR1

(2010) Evonne Say et al.   MOLECULAR CELL

The assembly of a GTPase–kinase signalling complex by a bacterial catalytic scaffold

(2010) Andrey S. Selyunin et al.   NATURE

p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

(2010) M. K. Y. Siu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth

(2010) B. W. Murray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why an A-Loop Phospho-Mimetic Fails to Activate PAK1: Understanding an Inaccessible Kinase State by Molecular Dynamics Simulations

(2010) Yuen-Wai Ng et al.   STRUCTURE

Pak4, a Novel Gab1 Binding Partner, Modulates Cell Migration and Invasion by the Met Receptor

(2009) G. N. Paliouras et al.   MOLECULAR AND CELLULAR BIOLOGY

A tale of two Paks

(2008) Luis E. Arias-Romero et al.   BIOLOGY OF THE CELL

PAK Is Regulated by PI3K, PIX, CDC42, and PP2Cα and Mediates Focal Adhesion Turnover in the Hyperosmotic Stress-induced p38 Pathway

(2008) Perry M. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling

(2008) W. Koh et al.   JOURNAL OF CELL SCIENCE