Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth

Copy number alterations in pancreatic cancer identify recurrentPAK4amplification

(2010) Shuaili Chen et al.   CANCER BIOLOGY & THERAPY

Novel Agents on the Horizon for Cancer Therapy

(2009) W. W. Ma et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting group II PAKs in cancer and metastasis

(2009) Jeyanthy Eswaran et al.   CANCER AND METASTASIS REVIEWS

Pak protein kinases and their role in cancer

(2009) Bettina Dummler et al.   CANCER AND METASTASIS REVIEWS

Discovery of a novel class of targeted kinase inhibitors that blocks protein kinase C signaling and ameliorates retinal vascular leakage in a diabetic rat model

(2009) Stephan Grant et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation

(2009) Yanmei Tian et al.   MECHANISMS OF DEVELOPMENT

PAK signaling in oncogenesis

(2009) P R Molli et al.   ONCOGENE

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

(2008) Sanjeev Shangary et al.   Annual Review of Pharmacology and Toxicology

A tale of two Paks

(2008) Luis E. Arias-Romero et al.   BIOLOGY OF THE CELL

Targeting the unactivated conformations of protein kinases for small molecule drug discovery

(2008) Gordon R Alton et al.   Expert Opinion on Drug Discovery

Rho GTPases in cancer cell biology

(2008) Francisco M. Vega et al.   FEBS LETTERS

Imaging of Cell Proliferation: Status and Prospects

(2008) J. R. Bading et al.   JOURNAL OF NUCLEAR MEDICINE

The Pak4 Protein Kinase Plays a Key Role in Cell Survival and Tumorigenesis in Athymic Mice

(2008) Y. Liu et al.   MOLECULAR CANCER RESEARCH

miR-29 miRNAs activate p53 by targeting p85α and CDC42

(2008) Seong-Yeon Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer

(2008) A. C. Kimmelman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UnPAKing the class differences among p21-activated kinases

(2008) Jeyanthy Eswaran et al.   TRENDS IN BIOCHEMICAL SCIENCES