Curcumin-loaded PLGA-PEG nanoparticles conjugated with B6 peptide for potential use in Alzheimer’s disease

Amyloid-β42 Activates the Expression of BACE1 Through the JNK Pathway

(2018) Michela Guglielmotto et al.   JOURNAL OF ALZHEIMERS DISEASE

The Mechanisms of Action of Curcumin in Alzheimer’s Disease

(2017) Mengxi Tang et al.   JOURNAL OF ALZHEIMERS DISEASE

Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes

(2017) Sarah Urnauer et al.   JOURNAL OF GENE MEDICINE

TDP-43 expression influences amyloidβ plaque deposition and tau aggregation

(2017) Stephani A. Davis et al.   NEUROBIOLOGY OF DISEASE

Curcumin administration suppress acetylcholinesterase gene expression in cadmium treated rats

(2017) Ayodele Jacob Akinyemi et al.   NEUROTOXICOLOGY

Anthocyanins encapsulated by PLGA@PEG nanoparticles potentially improved its free radical scavenging capabilities via p38/JNK pathway against Aβ1–42-induced oxidative stress

(2017) Faiz Ul Amin et al.   JOURNAL OF NANOBIOTECHNOLOGY

Physiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2

(2017) Riqiang Yan   Frontiers in Molecular Neuroscience

Graphene quantum dots conjugated neuroprotective peptide improve learning and memory capability

(2016) Songhua Xiao et al.   BIOMATERIALS

Curcumin ameliorates insulin signalling pathway in brain of Alzheimer’s disease transgenic mice

(2016) Hui-li Feng et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Synthesis, characterisation and preliminary investigation of the haemocompatibility of polyethyleneimine-grafted carboxymethyl chitosan for gene delivery

(2016) Xuan Liu et al.   Materials Science & Engineering C-Materials for Biological Applications

Curcumin Ameliorates Memory Decline via Inhibiting BACE1 Expression and β-Amyloid Pathology in 5×FAD Transgenic Mice

(2016) Kunmu Zheng et al.   MOLECULAR NEUROBIOLOGY

Optimization of Curcumin-Loaded PEG-PLGA Nanoparticles by GSH Functionalization: Investigation of the Internalization Pathway in Neuronal Cells

(2016) Ghislain Djiokeng Paka et al.   MOLECULAR PHARMACEUTICS

Curcumin, a Compound from Natural Sources, a True Scientific Challenge – A Review

(2016) Zorka Stanić   PLANT FOODS FOR HUMAN NUTRITION

Sialic acid (SA)-modified selenium nanoparticles coated with a high blood–brain barrier permeability peptide-B6 peptide for potential use in Alzheimer’s disease

(2015) Tiantian Yin et al.   Acta Biomaterialia

Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer’s disease

(2015) K. G. Goozee et al.   BRITISH JOURNAL OF NUTRITION

Rodent models for Alzheimer’s disease drug discovery

(2015) Daniela Puzzo et al.   Expert Opinion on Drug Discovery

The Stability, Sustained Release and Cellular Antioxidant Activity of Curcumin Nanoliposomes

(2015) Xing Chen et al.   MOLECULES

Amyloid-β pathology induced in humans

(2015) Mathias Jucker et al.   NATURE

Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits

(2015) Shu-Sheng Jiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological and therapeutic activities, and anticancer properties of curcumin

(2015) DONATELLA PERRONE et al.   Experimental and Therapeutic Medicine

PI3K/AKT/mTOR/p70S6K Pathway Is Involved in Aβ25-35-Induced Autophagy

(2015) Shengnuo Fan et al.   Biomed Research International

Curcumin nanoformulations: A review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment

(2014) Ornchuma Naksuriya et al.   BIOMATERIALS

Icariin Decreases the Expression of APP and BACE-1 and Reduces the β-amyloid Burden in an APP Transgenic Mouse Model of Alzheimer's Disease

(2014) Lan Zhang et al.   International Journal of Biological Sciences

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

B6 Peptide-Modified PEG-PLA Nanoparticles for Enhanced Brain Delivery of Neuroprotective Peptide

(2013) Zhongyang Liu et al.   BIOCONJUGATE CHEMISTRY

Curcumin attenuates amyloid-β-induced tau hyperphosphorylation in human neuroblastoma SH-SY5Y cells involving PTEN/Akt/GSK-3β signaling pathway

(2013) Han-Chang Huang et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Phosphodiesterase 7 inhibitor reduced cognitive impairment and pathological hallmarks in a mouse model of Alzheimer's disease

(2013) Rocio Perez-Gonzalez et al.   NEUROBIOLOGY OF AGING

Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor

(2012) Roger Prades et al.   BIOMATERIALS

Preparation and characterization of cationic curcumin nanoparticles for improvement of cellular uptake

(2012) Jinsong Liu et al.   CARBOHYDRATE POLYMERS

Curcumin loaded mixed micelles composed of Pluronic P123 and F68: Preparation, optimization and in vitro characterization

(2012) Liyan Zhao et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Pharmacokinetics of curcumin-loaded PLGA and PLGA–PEG blend nanoparticles after oral administration in rats

(2012) Najeh Maissar Khalil et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Curcumin Binds to Aβ1–40 Peptides and Fibrils Stronger Than Ibuprofen and Naproxen

(2012) Son Tung Ngo et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Nanobiotechnology-based strategies for crossing the blood–brain barrier

(2012) Kewal K Jain   Nanomedicine

Protective Effects of Curcumin on Amyloid-β-Induced Neuronal Oxidative Damage

(2012) Han-Chang Huang et al.   NEUROCHEMICAL RESEARCH

Curcumin Loaded-PLGA Nanoparticles Conjugated with Tet-1 Peptide for Potential Use in Alzheimer's Disease

(2012) Anila Mathew et al.   PLoS One

Targeting the brain with PEG–PLGA nanoparticles modified with phage-displayed peptides

(2011) Jingwei Li et al.   BIOMATERIALS

Preparation, characterization, in vitro drug release and biological studies of curcumin loaded dextran sulphate–chitosan nanoparticles

(2011) A. Anitha et al.   CARBOHYDRATE POLYMERS

The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems—A review

(2011) Susanne Fredenberg et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Dual-targeted polyplexes: One step towards a synthetic virus for cancer gene therapy

(2011) Yu Nie et al.   JOURNAL OF CONTROLLED RELEASE

REVIEW: Curcumin and Alzheimer's Disease

(2010) Tsuyoshi Hamaguchi et al.   CNS Neuroscience & Therapeutics

Hollow microcapsules built by layer by layer assembly for the encapsulation and sustained release of curcumin

(2010) S. Manju et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Curcumin-loaded PLGA-PEG-PLGA triblock copolymeric micelles: Preparation, pharmacokinetics and distribution in vivo

(2010) Zhimei Song et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain

(2010) Inge van Rooy et al.   JOURNAL OF CONTROLLED RELEASE

Synaptic degeneration in Alzheimer’s disease

(2009) Thomas Arendt   ACTA NEUROPATHOLOGICA

Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer

(2009) J. Shaikh et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH