Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism

Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis

(2011) R. Conti et al.   DIABETES

Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells

(2011) Orkhontuya Tsedensodnom et al.   EXPERIMENTAL CELL RESEARCH

Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo

(2010) J. Zhao et al.   DIABETOLOGIA

Identification of β-catenin binding regions in colon cancer cells using ChIP-Seq

(2010) Daniel Bottomly et al.   NUCLEIC ACIDS RESEARCH

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

(2009) K. Pilgaard et al.   DIABETOLOGIA

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets

(2009) P. Osmark et al.   DIABETOLOGIA

Adiponectin and thiazolidinedione targets CRTC2 to regulate hepatic gluconeogenesis

(2009) Young-Sil Yoon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Convergence of Wnt Signaling on the HNF4α-Driven Transcription in Controlling Liver Zonation

(2009) Marta Colletti et al.   GASTROENTEROLOGY

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

(2009) Luan Shu et al.   HUMAN MOLECULAR GENETICS

Transcription dynamics in a physiological process: β-Catenin signaling directs liver metabolic zonation

(2009) Cyril Torre et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Proteomic analysis of β-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway

(2009) Philippe Chafey et al.   PROTEOMICS

Transcription factor 7-like 2 polymorphism modulates glucose and lipid homeostasis, adipokine profile, and hepatocyte apoptosis in NASH

(2008) Giovanni Musso et al.   HEPATOLOGY

Glucagon-like Peptide-1 Activation of TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell Proliferation

(2008) Zhengyu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact ofTCF7L2rs7903146 on Insulin Secretion and Action in Young and Elderly Danish Twins

(2008) Lise Wegner et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells

(2008) P. Hatzis et al.   MOLECULAR AND CELLULAR BIOLOGY

Calpain-10 Gene and Protein Expression in Human Skeletal Muscle: Effect of Acute Lipid-Induced Insulin Resistance and Type 2 Diabetes

(2007) L. Norton et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM