IL-21 Is a Major Negative Regulator of IRF4-Dependent Lipolysis Affecting Tregs in Adipose Tissue and Systemic Insulin Sensitivity
出版年份 2014 全文链接
标题
IL-21 Is a Major Negative Regulator of IRF4-Dependent Lipolysis Affecting Tregs in Adipose Tissue and Systemic Insulin Sensitivity
作者
关键词
-
出版物
DIABETES
Volume 63, Issue 6, Pages 2086-2096
出版商
American Diabetes Association
发表日期
2014-01-16
DOI
10.2337/db13-0939
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Autocrine Regulation of IL-21 Production in Human T Lymphocytes
- (2014) F. Caprioli et al. JOURNAL OF IMMUNOLOGY
- Release from Regulatory T Cell-Mediated Suppression during the Onset of Tissue-Specific Autoimmunity Is Associated with Elevated IL-21
- (2014) L. E. Clough et al. JOURNAL OF IMMUNOLOGY
- ITCH Deficiency Protects From Diet-Induced Obesity
- (2013) A. Marino et al. DIABETES
- Interferon Regulatory Factor 4 Regulates Obesity-Induced Inflammation Through Regulation of Adipose Tissue Macrophage Polarization
- (2013) J. Eguchi et al. DIABETES
- Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay
- (2013) Loredana Fiorentino et al. EMBO Molecular Medicine
- Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus
- (2013) Stefan Kiechl et al. NATURE MEDICINE
- The MRC1/CD68 Ratio Is Positively Associated with Adipose Tissue Lipogenesis and with Muscle Mitochondrial Gene Expression in Humans
- (2013) José María Moreno-Navarrete et al. PLoS One
- TIMP3 Overexpression in Macrophages Protects From Insulin Resistance, Adipose Inflammation, and Nonalcoholic Fatty Liver Disease in Mice
- (2012) R. Menghini et al. DIABETES
- PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
- (2012) Daniela Cipolletta et al. NATURE
- Immunological complications of obesity
- (2012) Thirumala-Devi Kanneganti et al. NATURE IMMUNOLOGY
- The cellular and signaling networks linking the immune system and metabolism in disease
- (2012) Olivia Osborn et al. NATURE MEDICINE
- Inflammatory Mechanisms in Obesity
- (2011) Margaret F. Gregor et al. Annual Review of Immunology
- Alternative Macrophage Activation and Metabolism
- (2011) Justin I. Odegaard et al. Annual Review of Pathology-Mechanisms of Disease
- Transcriptional Control of Adipose Lipid Handling by IRF4
- (2011) Jun Eguchi et al. Cell Metabolism
- Increased Macrophage Migration Into Adipose Tissue in Obese Mice
- (2011) D. Y. Oh et al. DIABETES
- Innate immunity, insulin resistance and type 2 diabetes
- (2011) J. M. Fernández-Real et al. DIABETOLOGIA
- Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
- (2010) Aliki Kosteli et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulatory T cells in obesity: the leptin connection
- (2010) Giuseppe Matarese et al. TRENDS IN MOLECULAR MEDICINE
- Obesity predisposes to Th17 bias
- (2009) Shawn Winer et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
- (2009) Markus Feuerer et al. NATURE MEDICINE
- CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
- (2009) Satoshi Nishimura et al. NATURE MEDICINE
- Normalization of obesity-associated insulin resistance through immunotherapy
- (2009) Shawn Winer et al. NATURE MEDICINE
- Interleukin-21 as a new therapeutic target for immune-mediated diseases
- (2009) Giovanni Monteleone et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Regulatory T Cells and Immune Tolerance
- (2008) Shimon Sakaguchi et al. CELL
- Interferon Regulatory Factors Are Transcriptional Regulators of Adipogenesis
- (2008) Jun Eguchi et al. Cell Metabolism
- IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
- (2008) M. Huber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity
- (2007) Rosanne Spolski et al. Annual Review of Immunology
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