Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay

Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis

(2012) Aditya Murthy et al.   IMMUNITY

Circulating TNF Receptors 1 and 2 Predict Stage 3 CKD in Type 1 Diabetes

(2012) T. Gohda et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Circulating TNF Receptors 1 and 2 Predict ESRD in Type 2 Diabetes

(2012) M. A. Niewczas et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Dissociation of the Glucose and Lipid Regulatory Functions of FoxO1 by Targeted Knockin of Acetylation-Defective Alleles in Mice

(2011) Alexander S. Banks et al.   Cell Metabolism

Nutrient Sensing, Autophagy, and Diabetic Nephropathy

(2011) S. Kume et al.   DIABETES

Transcriptome Analysis of Human Diabetic Kidney Disease

(2011) K. I. Woroniecka et al.   DIABETES

The role of ADAM-mediated shedding in vascular biology

(2011) Daniela Dreymueller et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

JNK regulates FoxO-dependent autophagy in neurons

(2011) P. Xu et al.   GENES & DEVELOPMENT

The targeted podocyte

(2011) Agnes B. Fogo   JOURNAL OF CLINICAL INVESTIGATION

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

(2011) Markus Gödel et al.   JOURNAL OF CLINICAL INVESTIGATION

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

(2011) Ken Inoki et al.   JOURNAL OF CLINICAL INVESTIGATION

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

(2011) Guillaume Bollée et al.   NATURE MEDICINE

The Extending Network of FOXO Transcriptional Target Genes

(2010) Kristan E. van der Vos et al.   ANTIOXIDANTS & REDOX SIGNALING

FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis

(2010) Boyi Gan et al.   CANCER CELL

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

Modulation of Notch-1 Signaling Alleviates Vascular Endothelial Growth Factor–Mediated Diabetic Nephropathy

(2010) Chun-Liang Lin et al.   DIABETES

The role of Sirt1 in renal rejuvenation and resistance to stress

(2010) Karl A. Nath   JOURNAL OF CLINICAL INVESTIGATION

Sirt1 activation protects the mouse renal medulla from oxidative injury

(2010) Wenjuan He et al.   JOURNAL OF CLINICAL INVESTIGATION

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

(2010) Shinji Kume et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

(2010) Björn Hartleben et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytosolic FoxO1: alive and killing

(2010) René H. Medema et al.   NATURE CELL BIOLOGY

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

Kidney complications: Factors that protect the diabetic vasculature

(2010) Christian Rask-Madsen et al.   NATURE MEDICINE

The RAAS in the pathogenesis and treatment of diabetic nephropathy

(2010) Piero Ruggenenti et al.   Nature Reviews Nephrology

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SirT1

(2009) M. Cardellini et al.   DIABETES

The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes

(2009) P.-H. Groop et al.   DIABETES

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

(2009) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of TIMP3 Enhances Interstitial Nephritis and Fibrosis

(2009) Z. Kassiri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The cunning little vixen: Foxo and the cycle of life and death

(2009) Stephen M Hedrick   NATURE IMMUNOLOGY

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE