Calcitonin Gene-Related Peptide Receptor Antagonists: Beyond Migraine Pain—A Possible Analgesic Strategy for Osteoarthritis?

The CGRP receptor antagonist BIBN4096BS peripherally alleviates inflammatory pain in rats

(2013) Silke Hirsch et al.   PAIN

Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice

(2012) A. C. Ogbonna et al.   EUROPEAN JOURNAL OF PAIN

Evidence for anti-inflammatory and putative analgesic effects of a monoclonal antibody to calcitonin gene-related peptide

(2012) K.E. Bowler et al.   NEUROSCIENCE

Spontaneous firing in C-fibers and increased mechanical sensitivity in A-fibers of knee joint-associated mechanoreceptive primary afferent neurones during MIA-induced osteoarthritis in the rat

(2012) S. Kelly et al.   OSTEOARTHRITIS AND CARTILAGE

Localization of calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein 1 (RAMP1) in human gastrointestinal tract

(2012) Graeme S. Cottrell et al.   PEPTIDES

Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis

(2012) Niklas Schuelert et al.   ARTHRITIS RESEARCH & THERAPY

Neuropeptides Contribute to Peripheral Nociceptive Sensitization by Regulating Interleukin-1β Production in Keratinocytes

(2011) Xiaoyou Shi et al.   ANESTHESIA AND ANALGESIA

Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain

(2011) Sumihisa Orita et al.   BMC MUSCULOSKELETAL DISORDERS

Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis

(2011) Aisha Siddiqah Ahmed et al.   PAIN

Increased vascular penetration and nerve growth in the meniscus: a potential source of pain in osteoarthritis

(2010) S. Ashraf et al.   ANNALS OF THE RHEUMATIC DISEASES

Phenotypic alterations of neurons that innervate osteoarthritic joints in rats

(2010) Joana Ferreira-Gomes et al.   ARTHRITIS AND RHEUMATISM

Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate

(2010) Karel-Martijn Kalff et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Calcitonin gene-related peptide receptor antagonists for migraine

(2010) Michael JM Fischer   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Facilitation of Synaptic Transmission and Pain Responses by CGRP in the Amygdala of Normal Rats

(2010) Jeong S Han et al.   Molecular Pain

A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model

(2010) Pamela S. Puttfarcken et al.   PAIN

Sensitization in patients with painful knee osteoarthritis

(2010) Lars Arendt-Nielsen et al.   PAIN

Regulation of signal transduction by calcitonin gene-related peptide receptors

(2010) Christopher S Walker et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Possible sites of action of the new calcitonin gene-related peptide receptor antagonists

(2010) Sajedeh Eftekhari et al.   Therapeutic Advances in Neurological Disorders

Neurobiology of migraine

(2009) P.J. Goadsby et al.   NEUROSCIENCE

Nociceptor subpopulations involved in hyperalgesic priming

(2009) L.F. Ferrari et al.   NEUROSCIENCE

Calcitonin Gene-Related Peptide Receptor Inhibition Reduces Neuronal Activity Induced by Prolonged Increase in Nitric Oxide in the Rat Spinal Trigeminal Nucleus

(2008) S Kulchitsky et al.   CEPHALALGIA