Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease

Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease

(2014) G. A. Smith et al.   HUMAN MOLECULAR GENETICS

Animal models of Huntington's disease for translation to the clinic: Best practices

(2014) Liliana Menalled et al.   MOVEMENT DISORDERS

Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease

(2014) Nan Wang et al.   NATURE MEDICINE

Multiple Sources of Striatal Inhibition Are Differentially Affected in Huntington's Disease Mouse Models

(2013) C. Cepeda et al.   JOURNAL OF NEUROSCIENCE

The Q175 Mouse Model of Huntington’s Disease Shows Gene Dosage- and Age-Related Decline in Circadian Rhythms of Activity and Sleep

(2013) Dawn H. Loh et al.   PLoS One

Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease

(2012) Renata P. Lerner et al.   BRAIN RESEARCH BULLETIN

Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin

(2012) Anton Dvorzhak et al.   JOURNAL OF PHYSIOLOGY-LONDON

Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

(2012) Liliana B. Menalled et al.   PLoS One

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

(2012) Taneli Heikkinen et al.   PLoS One

Differential Electrophysiological Changes in Striatal Output Neurons in Huntington's Disease

(2011) V. M. Andre et al.   JOURNAL OF NEUROSCIENCE

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function

(2011) L.A. Raymond et al.   NEUROSCIENCE

Alterations in Striatal Synaptic Transmission are Consistent across Genetic Mouse Models of Huntington's Disease

(2010) Damian M Cummings et al.   ASN Neuro

Early autophagic response in a novel knock-in model of Huntington disease

(2010) Mary Y. Heng et al.   HUMAN MOLECULAR GENETICS

Differential Susceptibility to Excitotoxic Stress in YAC128 Mouse Models of Huntington Disease between Initiation and Progression of Disease

(2009) R. K. Graham et al.   JOURNAL OF NEUROSCIENCE

Age-Dependent Alterations of Corticostriatal Activity in the YAC128 Mouse Model of Huntington Disease

(2009) P. R. Joshi et al.   JOURNAL OF NEUROSCIENCE

Alterations in Cortical Excitation and Inhibition in Genetic Mouse Models of Huntington's Disease

(2009) D. M. Cummings et al.   JOURNAL OF NEUROSCIENCE

Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neurons

(2008) Carlos Cepeda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Altered Information Processing in the Prefrontal Cortex of Huntington's Disease Mouse Models

(2008) A. G. Walker et al.   JOURNAL OF NEUROSCIENCE

Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice

(2008) M. Gray et al.   JOURNAL OF NEUROSCIENCE

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

(2008) M.A. Hickey et al.   NEUROSCIENCE

Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease

(2008) J. Spampanato et al.   NEUROSCIENCE