Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease

Dendritic Spine Instability Leads to Progressive Neocortical Spine Loss in a Mouse Model of Huntington's Disease

(2013) R. P. Murmu et al.   JOURNAL OF NEUROSCIENCE

Mutant Huntingtin Alters Retrograde Transport of TrkB Receptors in Striatal Dendrites

(2013) G. Liot et al.   JOURNAL OF NEUROSCIENCE

Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data

(2013) Sarah J Tabrizi et al.   LANCET NEUROLOGY

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

Loss of corticostriatal and thalamostriatal synaptic terminals precedes striatal projection neuron pathology in heterozygous Q140 Huntington's disease mice

(2013) Y.P. Deng et al.   NEUROBIOLOGY OF DISEASE

dnc-1/dynactin 1 Knockdown Disrupts Transport of Autophagosomes and Induces Motor Neuron Degeneration

(2013) Kensuke Ikenaka et al.   PLoS One

Systemic Delivery of Recombinant Brain Derived Neurotrophic Factor (BDNF) in the R6/2 Mouse Model of Huntington’s Disease

(2013) Carmela Giampà et al.   PLoS One

The Q175 Mouse Model of Huntington’s Disease Shows Gene Dosage- and Age-Related Decline in Circadian Rhythms of Activity and Sleep

(2013) Dawn H. Loh et al.   PLoS One

Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes

(2012) The HD iPSC Consortium   Cell Stem Cell

Characterization of a rat model of Huntington’s disease based on targeted expression of mutanthuntingtinin the forebrain using adeno-associated viral vectors

(2012) Sanaz Gabery et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Circadian and sleep disorder in Huntington's disease

(2012) A. Jennifer Morton   EXPERIMENTAL NEUROLOGY

Relationship between BDNF expression in major striatal afferents, striatum morphology and motor behavior in the R6/2 mouse model of Huntington's disease

(2012) P. Samadi et al.   GENES BRAIN AND BEHAVIOR

Transgenic Mouse Model Expressing the Caspase 6 Fragment of Mutant Huntingtin

(2012) E. Waldron-Roby et al.   JOURNAL OF NEUROSCIENCE

Schizandrin, an Antioxidant Lignan fromSchisandra chinensis,Ameliorates Aβ1–42-Induced Memory Impairment in Mice

(2012) Di Hu et al.   Oxidative Medicine and Cellular Longevity

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

(2012) Taneli Heikkinen et al.   PLoS One

Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(CAG)150 Huntington's disease knock-in mouse

(2011) Zubeyde Bayram-Weston et al.   BRAIN RESEARCH BULLETIN

Light and electron microscopic characterization of the evolution of cellular pathology in HdhQ92 Huntington's disease knock-in mice

(2011) Zubeyde Bayram-Weston et al.   BRAIN RESEARCH BULLETIN

Light and electron microscopic characterization of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice

(2011) Zubeyde Bayram-Weston et al.   BRAIN RESEARCH BULLETIN

Light and electron microscopic characterization of the evolution of cellular pathology in YAC128 Huntington's disease transgenic mice

(2011) Zubeyde Bayram-Weston et al.   BRAIN RESEARCH BULLETIN

Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease

(2011) P Richards et al.   CELL DEATH AND DIFFERENTIATION

Rab GTPases, Membrane Trafficking and Diseases

(2011) Guangpu Li   CURRENT DRUG TARGETS

Cytoplasmic dynein in neurodegeneration

(2011) Judith Eschbach et al.   PHARMACOLOGY & THERAPEUTICS

Brain-Derived Neurotrophic Factor in Patients with Huntington's Disease

(2011) Chiara Zuccato et al.   PLoS One

A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons

(2010) Kerstin E. Braunstein et al.   HUMAN MOLECULAR GENETICS

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

(2009) Leslie Michels Thompson et al.   JOURNAL OF CELL BIOLOGY

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV  -Synucleinopathy

(2009) C. Y. Chung et al.   JOURNAL OF NEUROSCIENCE

Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity

(2009) X. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Disruption of Rab11 activity in a knock-in mouse model of Huntington's disease

(2009) Xueyi Li et al.   NEUROBIOLOGY OF DISEASE

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

(2009) Liliana Menalled et al.   NEUROBIOLOGY OF DISEASE

Short-Term Striatal Gene Expression Responses to Brain-Derived Neurotrophic Factor Are Dependent on MEK and ERK Activation

(2009) Ozgun Gokce et al.   PLoS One

Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression

(2009) Chee Yeun Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical and brainstem LTP-like plasticity in Huntington's disease

(2007) Domenica Crupi et al.   BRAIN RESEARCH BULLETIN