Environmental Endocrine Disruption of Energy Metabolism and Cardiovascular Risk

The Hijacking of Cellular Signaling and the Diabetes Epidemic: Mechanisms of Environmental Disruption of Insulin Action and Glucose Homeostasis

(2014) Robert M. Sargis   Diabetes & Metabolism Journal

Arsenic Exposure From Drinking Water, Arsenic Methylation Capacity, and Carotid Intima-Media Thickness in Bangladesh

(2013) Yu Chen et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Adiponectin increases macrophages cholesterol efflux and suppresses foam cell formation in patients with type 2 diabetes mellitus

(2013) Min Wang et al.   ATHEROSCLEROSIS

Low dose effects and non-monotonic dose responses for endocrine active chemicals: Science to practice workshop: Workshop summary

(2013) Claire Beausoleil et al.   CHEMOSPHERE

Environmental Chemicals and Type 2 Diabetes: An Updated Systematic Review of the Epidemiologic Evidence

(2013) Chin-Chi Kuo et al.   Current Diabetes Reports

Economic Costs of Diabetes in the U.S. in 2012

(2013)   DIABETES CARE

Hepatic DNA methylation modifications in early development of rats resulting from perinatal BPA exposure contribute to insulin resistance in adulthood

(2013) Y. Ma et al.   DIABETOLOGIA

Evaluation of the Association between Persistent Organic Pollutants (POPs) and Diabetes in Epidemiological Studies: A National Toxicology Program Workshop Review

(2013) Kyla W. Taylor et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effect of Bisphenol-A on insulin signal transduction and glucose oxidation in liver of adult male albino rat

(2013) Shankar Jayashree et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Cadmium exposure induces vascular injury due to endothelial oxidative stress: the role of local angiotensin II and COX-2

(2013) Jhuli Keli Angeli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Estrogen Normalizes Perinatal Nicotine–Induced Hypertensive Responses in Adult Female Rat Offspring

(2013) Daliao Xiao et al.   HYPERTENSION

In uteroand lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin modulates dysregulation of the lipid metabolism in mouse offspring fed a high-calorie diet

(2013) Etsuko Sugai et al.   JOURNAL OF APPLIED TOXICOLOGY

Cadmium exposure is accompanied by increased prevalence and future growth of atherosclerotic plaques in 64-year-old women

(2013) Björn Fagerberg et al.   JOURNAL OF INTERNAL MEDICINE

Nonylphenol disrupts the cardio-protective effects of 17^|^beta;-estradiol on ischemia/reperfusion injury in isolated hearts of guinea pig

(2013) Yan Wang et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Chronic Exposure to PCBs (Aroclor 1254) Exacerbates Obesity-Induced Insulin Resistance and Hyperinsulinemia in Mice

(2013) Sarah L. Gray et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Polybrominated Diphenyl Ethers Alter Hepatic Phosphoenolpyruvate Carboxykinase Enzyme Kinetics in Male Wistar Rats: Implications for Lipid and Glucose Metabolism

(2013) Jessica T. Nash et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Regioisomers of Phosphatidylcholine Containing DHA and Their Potential to Deliver DHA to the Brain: Role of Phospholipase Specificities

(2013) Su Chen et al.   LIPIDS

The Endocrine Disrupting Chemical Tolylfluanid Alters Adipocyte Metabolism via Glucocorticoid Receptor Activation

(2013) Brian A. Neel et al.   MOLECULAR ENDOCRINOLOGY

Circulating levels of persistent organic pollutants in relation to visceral and subcutaneous adipose tissue by abdominal MRI

(2013) Vendela Roos et al.   Obesity

Cadmium Induces Apoptosis in Pancreatic β-Cells through a Mitochondria-Dependent Pathway: The Role of Oxidative Stress-Mediated c-Jun N-Terminal Kinase Activation

(2013) Kai-Chih Chang et al.   PLoS One

Perinatal Bisphenol A Exposure and Adult Glucose Homeostasis: Identifying Critical Windows of Exposure

(2013) Jingli Liu et al.   PLoS One

Diethylhexyl Phthalates Is Associated with Insulin Resistance via Oxidative Stress in the Elderly: A Panel Study

(2013) Jin Hee Kim et al.   PLoS One

Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells

(2013) M.G. Alves et al.   REPRODUCTIVE TOXICOLOGY

Metabolic disruption in male mice due to fetal exposure to low but not high doses of bisphenol A (BPA): Evidence for effects on body weight, food intake, adipocytes, leptin, adiponectin, insulin and glucose regulation

(2013) Brittany M. Angle et al.   REPRODUCTIVE TOXICOLOGY

Increases in Oxidized Low-Density Lipoprotein and Other Inflammatory and Adhesion Molecules With a Concomitant Decrease in High-Density Lipoprotein in the Individuals Exposed to Arsenic in Bangladesh

(2013) Md. Rezaul Karim et al.   TOXICOLOGICAL SCIENCES

Arsenic augments the uptake of oxidized LDL by upregulating the expression of lectin-like oxidized LDL receptor in mouse aortic endothelial cells

(2013) Ekhtear Hossain et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Beijing ambient particle exposure accelerates atherosclerosis in ApoE knockout mice

(2013) Tian Chen et al.   TOXICOLOGY LETTERS

Angiotensin II-Induced Production of Mitochondrial Reactive Oxygen Species: Potential Mechanisms and Relevance for Cardiovascular Disease

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Air Pollution and Incidence of Hypertension and Diabetes Mellitus in Black Women Living in Los Angeles

(2012) Patricia F. Coogan et al.   CIRCULATION

Projections of Type 1 and Type 2 Diabetes Burden in the U.S. Population Aged

(2012) G. Imperatore et al.   DIABETES CARE

Adiponectin: mechanistic insights and clinical implications

(2012) A. T. Turer et al.   DIABETOLOGIA

Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses

(2012) Laura N. Vandenberg et al.   ENDOCRINE REVIEWS

GSTM1 , GSTT1 , and GSTP1 Polymorphisms and Associations between Air Pollutants and Markers of Insulin Resistance in Elderly Koreans

(2012) Jin Hee Kim et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Role of Environmental Chemicals in Diabetes and Obesity: A National Toxicology Program Workshop Review

(2012) Kristina A. Thayer et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Blood Concentrations of Persistent Organic Pollutants and Prediabetes and Diabetes in the General Population of Catalonia

(2012) Magda Gasull et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Identification of chemical components of combustion emissions that affect pro-atherosclerotic vascular responses in mice

(2012) Steven K. Seilkop et al.   INHALATION TOXICOLOGY

Diethyl Hexyl Phthalate (DEHP) is associated with insulin resistance in adipose tissue of male rat: Protective role of antioxidant vitamins (C & E)

(2012) Parsanathan Rajesh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Environmental arsenic exposure and serum matrix metalloproteinase-9

(2012) Jefferey L Burgess et al.   Journal of Exposure Science and Environmental Epidemiology

Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model

(2012) Ze Zheng et al.   JOURNAL OF HEPATOLOGY

Can persistent organic pollutants and plastic-associated chemicals cause cardiovascular disease?

(2012) L. Lind et al.   JOURNAL OF INTERNAL MEDICINE

Selective Thyromimetics Using Receptor and Tissue Selectivity Approaches: Prospects for Dyslipidemia

(2012) Amit A. Joharapurkar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1

(2012) Tingting Zhou et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Bisphenol A at concentrations found in human serum induces aneugenic effects in endothelial cells

(2012) Edna Ribeiro-Varandas et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Rapid Insulinotropic Action of Low Doses of Bisphenol-A on Mouse and Human Islets of Langerhans: Role of Estrogen Receptor β

(2012) Sergi Soriano et al.   PLoS One

Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures

(2012) Mohan Manikkam et al.   PLoS One

Reduced metabolic insulin sensitivity following sub-acute exposures to low levels of ambient fine particulate matter air pollution

(2012) Robert D. Brook et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cultured human peripheral blood mononuclear cells alter their gene expression when challenged with endocrine-disrupting chemicals

(2012) B. Wens et al.   TOXICOLOGY

Cyprodinil as an activator of aryl hydrocarbon receptor

(2012) Chien-Chung Fang et al.   TOXICOLOGY

Atrazine acts as an endocrine disrupter by inhibiting cAMP-specific phosphodiesterase-4

(2012) Marek Kucka et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arsenite activates NFκB through induction of C-reactive protein

(2012) Ingrid L. Druwe et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Methylated trivalent arsenicals are potent inhibitors of glucose stimulated insulin secretion by murine pancreatic islets

(2012) Christelle Douillet et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Activation of Aryl Hydrocarbon Receptor Induces Vascular Inflammation and Promotes Atherosclerosis in Apolipoprotein E−/− Mice

(2011) Dalei Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Circulating levels of bisphenol A and phthalates are related to carotid atherosclerosis in the elderly

(2011) P. Monica Lind et al.   ATHEROSCLEROSIS

Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: Involvement of the adaptive antioxidant response

(2011) Peng Xue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Chronic Fine Particulate Matter Exposure Induces Systemic Vascular Dysfunction via NADPH Oxidase and TLR4 Pathways

(2011) Thomas Kampfrath et al.   CIRCULATION RESEARCH

Perinatal Exposure to Bisphenol A at Reference Dose Predisposes Offspring to Metabolic Syndrome in Adult Rats on a High-Fat Diet

(2011) Jie Wei et al.   ENDOCRINOLOGY

Characterization of the Impaired Glucose Homeostasis Produced in C57BL/6 Mice by Chronic Exposure to Arsenic and High-Fat Diet

(2011) David S. Paul et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Circulating Levels of Persistent Organic Pollutants (POPs) and Carotid Atherosclerosis in the Elderly

(2011) P. Monica Lind et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Glucose and lipid homeostasis in adult rat is impaired by early-life exposure to perfluorooctane sulfonate

(2011) Ziquan Lv et al.   ENVIRONMENTAL TOXICOLOGY

Low doses of bisphenol a induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver

(2011) Alice Marmugi et al.   HEPATOLOGY

Enhanced insulin resistance in diet-induced obese rats exposed to fine particles by instillation

(2011) Yuan-Horng Yan et al.   INHALATION TOXICOLOGY

Urinary Bisphenol A (BPA) Concentration Associates with Obesity and Insulin Resistance

(2011) Tiange Wang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Endocrine disrupting properties of perfluorooctanoic acid

(2011) Sally S. White et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Lipid, Lipoproteins, Total Antioxidant Status and Organ Changes in Rats Administered High Doses of Cadmium Chloride

(2011) M.J. Olisekodiaka et al.   MEDICAL PRINCIPLES AND PRACTICE

Endocrine disruptors in the etiology of type 2 diabetes mellitus

(2011) Paloma Alonso-Magdalena et al.   Nature Reviews Endocrinology

Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues

(2011) Zhaobin Xu et al.   Particle and Fibre Toxicology

Polychlorinated biphenyl 77 augments angiotensin II-induced atherosclerosis and abdominal aortic aneurysms in male apolipoprotein E deficient mice

(2011) Violeta Arsenescu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Atherosclerosis induced by arsenic in drinking water in rats through altering lipid metabolism

(2011) Tain-Junn Cheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Diabetes and Coronary Heart Disease as Risk Factors for Mortality in Older Adults

(2010) Mercedes R. Carnethon et al.   AMERICAN JOURNAL OF MEDICINE

Endocrine Disrupting Chemicals Targeting Estrogen Receptor Signaling: Identification and Mechanisms of Action

(2010) Erin K. Shanle et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Arsenic Inhibits Myogenic Differentiation and Muscle Regeneration

(2010) Yuan-Peng Yen et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Low Dose of Some Persistent Organic Pollutants Predicts Type 2 Diabetes: A Nested Case–Control Study

(2010) Duk-Hee Lee et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bisphenol A Exposure during Pregnancy Disrupts Glucose Homeostasis in Mothers and Adult Male Offspring

(2010) Paloma Alonso-Magdalena et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Low-Level Arsenic Impairs Glucose-Stimulated Insulin Secretion in Pancreatic Beta Cells: Involvement of Cellular Adaptive Response to Oxidative Stress

(2010) Jingqi Fu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Inflammatory response and insulin signaling alteration induced by PCB77

(2010) Jing Wang et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

2,3,7,8-Tetrachlorodibenzo-p-Dioxin Impairs an Insulin Signaling Pathway through the Induction of Tumor Necrosis Factor-α in Adipocytes

(2010) Shin Nishiumi et al.   TOXICOLOGICAL SCIENCES

Long-Term Consequences of Fetal and Neonatal Nicotine Exposure: A Critical Review

(2010) Jennifer E. Bruin et al.   TOXICOLOGICAL SCIENCES

Omega-3 fatty acid oxidation products prevent vascular endothelial cell activation by coplanar polychlorinated biphenyls

(2010) Zuzana Majkova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Therapeutic Implications of Diabetes in Cardiovascular Disease

(2009) Biju Cherian et al.   AMERICAN JOURNAL OF THERAPEUTICS

Cadmium Is a Novel and Independent Risk Factor for Early Atherosclerosis Mechanisms and In Vivo Relevance

(2009) Barbara Messner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ambient Air Pollution Exaggerates Adipose Inflammation and Insulin Resistance in a Mouse Model of Diet-Induced Obesity

(2009) Qinghua Sun et al.   CIRCULATION

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement

(2009) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS

Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome

(2009) Jérôme Ruzzin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Neonatal Organophosphorus Pesticide Exposure Alters the Developmental Trajectory of Cell-Signaling Cascades Controlling Metabolism: Differential Effects of Diazinon and Parathion

(2009) Abayomi A. Adigun et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Exposures to Particulate Matter and Polycyclic Aromatic Hydrocarbons and Oxidative Stress in Schoolchildren

(2009) Sanghyuk Bae et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Tributyltin causes obesity and hepatic steatosis in male mice

(2009) Zhenghong Zuo et al.   ENVIRONMENTAL TOXICOLOGY

Dioxin Exposure and Insulin Resistance in Taiwanese Living Near a Highly Contaminated Area

(2009) Jung-Wei Chang et al.   EPIDEMIOLOGY

Triphenyltin chloride induces glucose intolerance by the suppression of insulin release from hamster pancreatic ß-cells

(2009) K. Ogino et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Molecular physiology of weight regulation in mice and humans

(2009) R L Leibel   INTERNATIONAL JOURNAL OF OBESITY

Aryl hydrocarbon receptor-mediated effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on glucose-stimulated insulin secretion in mice

(2009) Hisaka Kurita et al.   JOURNAL OF APPLIED TOXICOLOGY

Environmental estrogens and obesity

(2009) Retha R. Newbold et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Chronic Exposure to the Herbicide, Atrazine, Causes Mitochondrial Dysfunction and Insulin Resistance

(2009) Soo Lim et al.   PLoS One

Cadmium reduces adipocyte size and expression levels of adiponectin and Peg1/Mest in adipose tissue

(2009) Takashige Kawakami et al.   TOXICOLOGY

Up-regulation of endothelial monocyte chemoattractant protein-1 by coplanar PCB77 is caveolin-1-dependent

(2009) Zuzana Majkova et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arsenate-induced maternal glucose intolerance and neural tube defects in a mouse model

(2009) Denise S. Hill et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inorganic mercury causes pancreatic β-cell death via the oxidative stress-induced apoptotic and necrotic pathways

(2009) Ya Wen Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Levels of Tobacco-Specific Nitrosamines and Polycyclic Aromatic Hydrocarbons in Mainstream Smoke from Different Tobacco Varieties

(2008) Y. S. Ding et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Cytokines and atherosclerosis: a comprehensive review of studies in mice

(2008) R. Kleemann et al.   CARDIOVASCULAR RESEARCH

Hypertension, Cardiac Hypertrophy, and Impaired Vascular Relaxation Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin are Associated with Increased Superoxide

(2008) Phillip G. Kopf et al.   Cardiovascular Toxicology

Enhanced zinc consumption prevents cadmium-induced alterations in lipid metabolism in male rats

(2008) Joanna Rogalska et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Bisphenol A at Environmentally Relevant Doses Inhibits Adiponectin Release from Human Adipose Tissue Explants and Adipocytes

(2008) Eric R. Hugo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Polychlorinated Biphenyl-77 Induces Adipocyte Differentiation and Proinflammatory Adipokines and Promotes Obesity and Atherosclerosis

(2008) Violeta Arsenescu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Association of polychlorinated biphenyls with hypertension in the 1999–2002 National Health and Nutrition Examination Survey

(2008) Charles J. Everett et al.   ENVIRONMENTAL RESEARCH

Association of Urinary Bisphenol A Concentration With Medical Disorders and Laboratory Abnormalities in Adults

(2008) Iain A. Lang   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener

(2007) Vicki M. Richardson et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY