Main path and byways: non-vesicular glutamate release by system xc−as an important modifier of glutamatergic neurotransmission
出版年份 2015 全文链接
标题
Main path and byways: non-vesicular glutamate release by system xc−as an important modifier of glutamatergic neurotransmission
作者
关键词
-
出版物
JOURNAL OF NEUROCHEMISTRY
Volume 135, Issue 6, Pages 1062-1079
出版商
Wiley
发表日期
2015-09-04
DOI
10.1111/jnc.13348
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Crucial role of astrocytes in temporal lobe epilepsy
- (2016) C. Steinhäuser et al. NEUROSCIENCE
- Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc−, the Na+-independent glutamate–cystine exchanger
- (2015) Jing Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-Dependent upregulation of glutathione synthesis
- (2015) Yan He et al. GLIA
- Cystathionine Is a Novel Substrate of Cystine/Glutamate Transporter
- (2015) Sho Kobayashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease
- (2015) Kou Takahashi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inhibition of SystemXc−Transporter Attenuates Autoimmune Inflammatory Demyelination
- (2015) Kirsten S. Evonuk et al. JOURNAL OF IMMUNOLOGY
- Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells
- (2015) Katja Linher-Melville et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
- (2015) Yu Tang et al. MOLECULAR NEUROBIOLOGY
- Global quantitative analysis of phosphorylation underlying phencyclidine signaling and sensorimotor gating in the prefrontal cortex
- (2015) D B McClatchy et al. MOLECULAR PSYCHIATRY
- MPTP-induced parkinsonism in mice alters striatal and nigral xCT expression but is unaffected by the genetic loss of xCT
- (2015) Eduard Bentea et al. NEUROSCIENCE LETTERS
- Lack of effect of Theiler’s murine encephalomyelitis virus infection on system xc−
- (2015) Ellen Merckx et al. NEUROSCIENCE LETTERS
- Absence of system xc- in mice decreases anxiety and depressive-like behavior without affecting sensorimotor function or spatial vision
- (2015) Eduard Bentea et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma
- (2015) E Singer et al. Cell Death & Disease
- Repeated cycles of chronic intermittent ethanol exposure increases basal glutamate in the nucleus accumbens of mice without affecting glutamate transport
- (2015) William C. Griffin et al. Frontiers in Pharmacology
- Behavioral characterization of system xc- mutant mice
- (2014) Elizabeth A. McCullagh et al. BEHAVIOURAL BRAIN RESEARCH
- System xC− is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice
- (2014) Pinar Mesci et al. BRAIN
- IGF-I Regulates Redox Status in Breast Cancer Cells by Activating the Amino Acid Transport Molecule xC−
- (2014) Yuzhe Yang et al. CANCER RESEARCH
- Sigma receptor 1 modulates ER stress and Bcl2 in murine retina
- (2014) Yonju Ha et al. CELL AND TISSUE RESEARCH
- Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damage
- (2014) Federico N. Soria et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulation of Hippocampal Synaptic Strength by Glial xCT
- (2014) L. E. Williams et al. JOURNAL OF NEUROSCIENCE
- Transcription Factor Nrf1 Negatively Regulates the Cystine/Glutamate Transporter and Lipid-Metabolizing Enzymes
- (2014) T. Tsujita et al. MOLECULAR AND CELLULAR BIOLOGY
- Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington’s disease
- (2014) Bindu D. Paul et al. NATURE
- Dysregulation of system xc− expression induced by mutant huntingtin in a striatal neuronal cell line and in R6/2 mice
- (2014) Natalie M. Frederick et al. NEUROCHEMISTRY INTERNATIONAL
- Sulfasalazine and temozolomide with radiation therapy for newly diagnosed glioblastoma
- (2014) Satoru Takeuchi et al. NEUROLOGY INDIA
- Stress-induced inhibition of nonsense-mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11
- (2014) L Martin et al. ONCOGENE
- Effects of ceftriaxone on ethanol intake: a possible role for xCT and GLT-1 isoforms modulation of glutamate levels in P rats
- (2014) Hasan Alhaddad et al. PSYCHOPHARMACOLOGY
- Behavioral assessment of acute inhibition of system xc - in rats
- (2014) Victoria Lutgen et al. PSYCHOPHARMACOLOGY
- Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor
- (2014) Jon M. Resch et al. SYNAPSE
- Phosphoinositide 3-Kinases Upregulate System xc− via Eukaryotic Initiation Factor 2α and Activating Transcription Factor 4 – A Pathway Active in Glioblastomas and Epilepsy
- (2013) Jan Lewerenz et al. ANTIOXIDANTS & REDOX SIGNALING
- Inhibition of the Group I mGluRs Reduces Acute Brain Damage and Improves Long-Term Histological Outcomes after Photothrombosis-Induced Ischaemia
- (2013) Hailong Li et al. ASN Neuro
- FGF-2 induces neuronal death through upregulation of system xc-
- (2013) XiaoQian Liu et al. BRAIN RESEARCH
- Regulation of system xc− in the SOD1-G93A mouse model of ALS
- (2013) Rebecca Albano et al. EXPERIMENTAL NEUROLOGY
- Using EAE to better understand principles of immune function and autoimmune pathology
- (2013) Manu Rangachari et al. JOURNAL OF AUTOIMMUNITY
- Alpha-lipoic acid effects on brain glial functions accompanying double-stranded RNA antiviral and inflammatory signaling
- (2013) Philip O. Scumpia et al. NEUROCHEMISTRY INTERNATIONAL
- Novel di-aryl-substituted isoxazoles act as noncompetitive inhibitors of the system xc- cystine/glutamate exchanger
- (2013) J.L. Newell et al. NEUROCHEMISTRY INTERNATIONAL
- Dysregulation of Dopamine and Glutamate Release in the Prefrontal Cortex and Nucleus Accumbens Following Methamphetamine Self-Administration and During Reinstatement in Rats
- (2013) Aram Parsegian et al. NEUROPSYCHOPHARMACOLOGY
- Increased Extracellular Glutamate In the Nucleus Accumbens Promotes Excessive Ethanol Drinking in Ethanol Dependent Mice
- (2013) William C Griffin III et al. NEUROPSYCHOPHARMACOLOGY
- JAKs and STATs in Immunity, Immunodeficiency, and Cancer
- (2013) John J. O'Shea et al. NEW ENGLAND JOURNAL OF MEDICINE
- Role of mGluR5 neurotransmission in reinstated cocaine-seeking
- (2012) Xiusong Wang et al. ADDICTION BIOLOGY
- The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
- (2012) Jan Lewerenz et al. ANTIOXIDANTS & REDOX SIGNALING
- Non-Cell Autonomous Influence of the Astrocyte System xc− on Hypoglycaemic Neuronal Cell Death
- (2012) Nicole A Jackman et al. ASN Neuro
- Impaired long-term potentiation and long-term memory deficits in xCT-deficientsutmice
- (2012) Yan Li et al. BIOSCIENCE REPORTS
- Regulators of synaptic transmission: Roles in the pathogenesis and treatment of epilepsy
- (2012) Pablo M. Casillas-Espinosa et al. EPILEPSIA
- Sulfasalazine for brain cancer fits
- (2012) Harald Sontheimer et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells
- (2012) Márcio Ribeiro et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ceftriaxone Normalizes Nucleus Accumbens Synaptic Transmission, Glutamate Transport, and Export following Cocaine Self-Administration and Extinction Training
- (2012) H. Trantham-Davidson et al. JOURNAL OF NEUROSCIENCE
- Increased xCT Expression Correlates With Tumor Invasion and Outcome in Patients With Glioblastomas
- (2012) Satoru Takeuchi et al. NEUROSURGERY
- N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: Behavioral and biochemical analyses in rats
- (2012) Irena Smaga et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Ceftriaxone prevents the induction of cocaine sensitization and produces enduring attenuation of cue- and cocaine-primed reinstatement of cocaine-seeking
- (2011) Ilan Sondheimer et al. BEHAVIOURAL BRAIN RESEARCH
- Antioxidants in Huntington's disease
- (2011) Ashu Johri et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression
- (2011) J Lewerenz et al. CELL DEATH AND DIFFERENTIATION
- System xc− regulates microglia and macrophage glutamate excitotoxicity in vivo
- (2011) Kristina A. Kigerl et al. EXPERIMENTAL NEUROLOGY
- Increased expression of cystine/glutamate antiporter in multiple sclerosis
- (2011) Olatz Pampliega et al. Journal of Neuroinflammation
- Loss of System xFormula Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility
- (2011) D. De Bundel et al. JOURNAL OF NEUROSCIENCE
- SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments
- (2011) Peter I. Joyce et al. MAMMALIAN GENOME
- Glutamate release by primary brain tumors induces epileptic activity
- (2011) Susan C Buckingham et al. NATURE MEDICINE
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- Functional upregulation of system xc− by fibroblast growth factor-2
- (2011) XiaoQian Liu et al. NEUROPHARMACOLOGY
- Distinct Neurochemical Adaptations Within the Nucleus Accumbens Produced by a History of Self-Administered vs Non-Contingently Administered Intravenous Methamphetamine
- (2011) Kevin D Lominac et al. NEUROPSYCHOPHARMACOLOGY
- Dopaminergic neurons of system xc−-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity
- (2010) Ann Massie et al. FASEB JOURNAL
- Regulation of System xc−Activity and Expression in Astrocytes by Interleukin-1β
- (2010) Nicole A. Jackman et al. GLIA
- Extinction Training after Cocaine Self-Administration Induces Glutamatergic Plasticity to Inhibit Cocaine Seeking
- (2010) L. A. Knackstedt et al. JOURNAL OF NEUROSCIENCE
- N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a Novel Metabotropic Glutamate 2 Potentiator with Potential Anxiolytic/Antidepressant Properties: In Vivo Profiling Suggests a Link between Behavioral and Central Nervous System Neurochemical Changes
- (2010) M. J. Fell et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
- (2010) Giles E. Hardingham et al. NATURE REVIEWS NEUROSCIENCE
- Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse
- (2010) K. Moussawi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Bermuda Triangle of cocaine-induced neuroadaptations
- (2010) Marina E. Wolf TRENDS IN NEUROSCIENCES
- Ceftriaxone Restores Glutamate Homeostasis and Prevents Relapse to Cocaine Seeking
- (2009) Lori A. Knackstedt et al. BIOLOGICAL PSYCHIATRY
- Isoxazole analogues bind the System xc- transporter: Structure–activity relationship and pharmacophore model
- (2009) Sarjubhai A. Patel et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of Sulfasalazine for the treatment of progressing malignant gliomas in adults
- (2009) Pierre A Robe et al. BMC CANCER
- β-N-methylamino-l-alanine induces oxidative stress and glutamate release through action on system Xc−
- (2009) XiaoQian Liu et al. EXPERIMENTAL NEUROLOGY
- Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxonein vitro
- (2009) Jan Lewerenz et al. JOURNAL OF NEUROCHEMISTRY
- Molecular regulation of antioxidant ability in the hippocampus of EL mice
- (2008) Mayuko Takaki et al. BRAIN RESEARCH
- Basal Levels of eIF2α Phosphorylation Determine Cellular Antioxidant Status by Regulating ATF4 and xCT Expression
- (2008) Jan Lewerenz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neurodegeneration in multiple sclerosis: The role of oxidative stress and excitotoxicity
- (2008) R.E. Gonsette JOURNAL OF THE NEUROLOGICAL SCIENCES
- Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving
- (2008) Kelly L. Conrad et al. NATURE
- Small interfering RNA–mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema
- (2008) Nicolai E Savaskan et al. NATURE MEDICINE
- Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
- (2008) Gerard Sanacora et al. NATURE REVIEWS DRUG DISCOVERY
- Neuroprotection for ischemic stroke: Past, present and future
- (2008) Myron D. Ginsberg NEUROPHARMACOLOGY
- Time-dependent changes in striatal xCT protein expression in hemi-Parkinson rats
- (2008) Ann Massie et al. NEUROREPORT
- Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse
- (2008) B.R. Miller et al. NEUROSCIENCE
- Current Status of Neuroprotection for Cerebral Ischemia: Synoptic Overview
- (2008) M. D. Ginsberg STROKE
- Synergism between fluoxetine and the mGlu2/3 receptor agonist, LY379268, in an in vitro model for antidepressant drug-induced neurogenesis
- (2007) F. Matrisciano et al. NEUROPHARMACOLOGY
- Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function
- (2003) Steven W. Barger et al. JOURNAL OF NEUROCHEMISTRY
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