Article
Nanoscience & Nanotechnology
Keivan Asadi, Junghoon Yeom, Hanna Cho
Summary: Investigating internal resonance (IR) mechanisms in micro/nanoresonators reveals that intermodal coupling between second and third flexural modes in asymmetric structures provides an optimal condition for strong IR, with high energy transfer to the resonated mode. This study introduces design strategies that can be easily integrated into typical micro/nanoelectromechanical systems, offering potential for paradigm-shifting applications in micro/nanosystems.
MICROSYSTEMS & NANOENGINEERING
(2021)
Editorial Material
Multidisciplinary Sciences
Telmo O. Paiva, Albertus Viljoen, Yves F. Dufrene
Summary: Advancements in atomic force microscopy (AFM) techniques and methodologies in microbiology have enhanced our understanding of microbial cell surfaces. Recent studies have shown that AFM imaging of cells and membranes at or near molecular resolution enables detailed visualization of membrane-drug interactions.
NATURE COMMUNICATIONS
(2022)
Article
Physics, Applied
Shiquan Lin, Zhong Lin Wang
Summary: Inspired by TENG, scanning TENG is proposed for local surface charge density measurement using atomic force microscopy. The technique taps a conductive tip above a charged dielectric surface to induce an AC, with Fourier analysis showing a linear relation to surface charge density. Results demonstrate its power in probing nanoscale charge transfer in contact-electrification.
APPLIED PHYSICS LETTERS
(2021)
Article
Chemistry, Physical
Miles F. Beaux, Reuben J. Peterson, Igor O. Usov
Summary: Atomic force microscopy was used to map the topography and qualitative mechanical characteristics of gallium-stabilized delta-phase plutonium coupons. The initial rough and heterogeneous surface of plutonium was observed, along with distinct striation patterns in qualitative nanomechanical mapping. Investigation suggested that the striations were not measurement artifacts or plutonium-specific features, and were influenced by mechanical working of the surface.
SURFACES AND INTERFACES
(2021)
Article
Polymer Science
Jin Hau Lew, Omar K. Matar, Erich A. Mueller, Paul F. Luckham, Adrielle Sousa Santos, Maung Maung Myo Thant
Summary: In this study, the interaction between hydrolysed polyacrylamide (HPAM) with different molecular weights and calcium carbonate (CaCO3) was investigated using atomic force microscopy (AFM). The results showed that the presence of polymers, salt concentration, and molecular weight have significant effects on the interaction.
Article
Chemistry, Physical
Francisco J. Solis, Monica Olvera de la Cruz
Summary: This article discusses the interactions between charged particles and induced polarization charge on solid-liquid or liquid-liquid interfaces with dielectric contrast, as well as the self-energy of charged particles near rough surfaces. Results show that the local convexity and concavity of the surface affect the repulsion of ions.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Chemistry, Applied
Qiuyu Li, Shixiang Yao, Lili Deng, Kaifang Zeng
Summary: Postharvest granulation in citrus fruit is a severe physiological disorder that may be related to pectin metabolism. Changes in fruit quality and pectin metabolism, such as an increase in various soluble pectins and pectin methylesterase activity, were observed during granulation. Remodeling of the complex network of pectin may immobilize free water in juice sacs and induce gelation, further promoting the granulation process.
Article
Chemistry, Applied
Beibei He, Shancan Wang, Ping Lan, Weihua Wang, Jie Zhu
Summary: The effects of environmental temperature and relative humidity on the surface ultrastructure of carboxymethyl cellulose (CMC) films were investigated, and the mechanical and water vapor barrier properties were evaluated. The results showed that temperature and humidity influenced the size and numbers of holes on the film surface, which in turn affected the mechanical properties and water vapor permeability of the films.
Article
Cell Biology
Elma Sakinatus Sajidah, Keesiang Lim, Tomoyoshi Yamano, Goro Nishide, Yujia Qiu, Takeshi Yoshida, Hanbo Wang, Akiko Kobayashi, Masaharu Hazawa, Firli R. P. Dewi, Rikinari Hanayama, Toshio Ando, Richard W. Wong
Summary: Small extracellular vesicles (sEVs) play a crucial role in cell communication and can be used for drug delivery and structural characterization of nanoparticles. The high-speed atomic force microscopy (HS-AFM) can evaluate the structural changes of sEVs under different physicochemical stresses.
JOURNAL OF EXTRACELLULAR VESICLES
(2022)
Article
Mechanics
Abbasali Abouei Mehrizi, Qiao Liu, Hao Wang
Summary: The extended thin-film region adjacent to the contact line plays a crucial role in heat transfer and wetting dynamics by enhancing heat transfer and influencing contact line morphology. The study focused on advancing contact line morphology induced by water vapor condensation at low rates. Results showed that the morphology of the liquid film in this process differs from nonvolatile cases, with a precursor nanofilm and nanodroplets detected beyond the contact line.
Article
Chemistry, Analytical
Xinyu Li, Li Zhao, Rongrong Feng, Xiaowei Du, Zelin Guo, Yu Meng, Yulan Zou, Wenchao Liao, Qiyuan Liu, Yaohuan Sheng, Gaowei Zhao, Haijian Zhong, Weidong Zhao
Summary: Using atomic force microscopy, it was found that Na(V)1.5 is irregularly distributed on the surfaces of both normal and cancer breast cells, with higher expression on cancer cells. The stability of the Na(V)1.5-antibody complex is higher on normal breast cells compared to cancer breast cells. These findings provide insights into the interactions of ion channel-antibody systems and the role of sodium channels in tumor metastasis and invasion.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Multidisciplinary
Niklas A. Weber, Hendrik Schmidt, Tim Sievert, Christian Jooss, Friedrich Guethoff, Vasily Moshneaga, Konrad Samwer, Matthias Krueger, Cynthia A. Volkert
Summary: This study investigates the mechanism of friction at sliding contacts, proposing that friction can be explained by considering the damping of stick-slip pulses. The findings provide a basis for reconciling controversies in literature studies on friction and suggest possible tactics for controlling friction.
Article
Physiology
Jinhui Tao, Emma Hanson, Alice C. Dohnalkova, Garry W. Buchko, Biao Jin, Wendy J. Shaw, Barbara J. Tarasevich
Summary: This study investigates the adsorption interactions between amelogenin and calcium phosphate minerals using mechanistic probes. The results reveal the importance of the oligomer quaternary structure in controlling amelogenin adsorption and hydroxyapatite (HAP) mineralization.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Cell Biology
Yuan Qiu, Chen-Chi Chien, Basile Maroulis, Jiani Bei, Angelo Gaitas, Bin Gong
Summary: This article presents a review of the applications of atomic force microscopy (AFM) and fluidic atomic force microscopy (fluidFM) in single-cell studies. It discusses the use of AFM in studying single cells, extracellular vesicles, colloidal force spectroscopy, and single-cell adhesion measurements. FluidFM, a combination of microfluidics and AFM, allows for biological, pathological, and pharmacological studies on single cells in a liquid environment. The review focuses on the capabilities of fluidFM in measuring adhesion, binding forces, and manipulating single cells, as well as its applications in patch clamping and mass measurements.
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Emilie Gachon, Patrick Mesquida
Summary: Collagen fibrils exhibit a surface charge dependency on longitudinal strain, becoming more positive within 10% strain and more negative between 10% to 17% strain. This change is correlated with fibril stiffness and may be influenced by structural rearrangements. Kelvin-probe force microscopy testing on fibrils attached to an extensible, thin polymer film allows for the determination of electrical surface potential.
Article
Neurosciences
Phillip F. Giannopoulos, Jin Chu, Margaret Sperow, Jian-Guo Li, W. Haung Yu, Lynn G. Kirby, Mary Abood, Domenico Pratico
BIOLOGICAL PSYCHIATRY
(2015)
Article
Cell Biology
Jeffrey L. Barr, Elena Deliu, G. Cristina Brailoiu, Pingwei Zhao, Guang Yan, Mary E. Abood, Ellen M. Unterwald, Eugen Brailoiu
Article
Substance Abuse
J. Palma, M. E. Abood, K. Benamar
DRUG AND ALCOHOL DEPENDENCE
(2015)
Editorial Material
Chemistry, Medicinal
Mary E. Abood
JOURNAL OF MEDICINAL CHEMISTRY
(2016)
Article
Pharmacology & Pharmacy
Linda Console-Bram, Eugen Brailoiu, Gabriela Cristina Brailoiu, Haleli Sharir, Mary E. Abood
BRITISH JOURNAL OF PHARMACOLOGY
(2014)
Article
Biochemistry & Molecular Biology
Derek M. Shore, Gemma L. Baillie, Dow H. Hurst, Frank Navas, Herbert H. Seltzman, Jahan P. Marcu, Mary E. Abood, Ruth A. Ross, Patricia H. Reggio
JOURNAL OF BIOLOGICAL CHEMISTRY
(2014)
Article
Biochemistry & Molecular Biology
Pingwei Zhao, Tom R. Lane, Helen G. L. Gao, Dow P. Hurst, Evangelia Kotsikorou, Long Le, Eugen Brailoiu, Patricia H. Reggio, Mary E. Abood
JOURNAL OF BIOLOGICAL CHEMISTRY
(2014)
Article
Chemistry, Medicinal
Valentina Lucchesi, Dow P. Hurst, Derek M. Shore, Simone Bertini, Brandie M. Ehrmann, Marco Allara, Lyle Lawrence, Alessia Ligresti, Filippo Minutolo, Giuseppe Saccomanni, Haleli Sharir, Marco Macchia, Vincenzo Di Marzo, Mary E. Abood, Patricia H. Reggio, Clementina Manera
JOURNAL OF MEDICINAL CHEMISTRY
(2014)
Article
Multidisciplinary Sciences
Yaping Lin-Moshier, Michael V. Keebler, Robert Hooper, Michael J. Boulware, Xiaolong Liu, Dev Churamani, Mary E. Abood, Timothy F. Walseth, Eugen Brailoiu, Sandip Patel, Jonathan S. Marchant
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2014)
Article
Chemistry, Medicinal
Paula Morales, Ana Lago-Fernandez, Dow P. Hurst, Noori Sotudeh, Eugen Brailoiu, Patricia H. Reggio, Mary E. Abood, Nadine Jagerovic
JOURNAL OF MEDICINAL CHEMISTRY
(2020)
Article
Pharmacology & Pharmacy
Luciana M. Leo, Rufaida Al-Zoubi, Dow P. Hurst, Anna P. Stephan, Pingwei Zhao, Douglas G. Tilley, Elke Miess, Stefan Schulz, Mary E. Abood, Patricia H. Reggio
Summary: This study discovered the crucial role of amino acids in the NPXXY motif of the CB1 receptor in beta-arrestin recruitment. These findings reveal a novel mechanism for beta-arrestin recruitment and suggest the significance of amino acids in the NPXXY motif in the specific conformational state of GPCRs.
CANNABIS AND CANNABINOID RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Henry Blanton, Sabiha Armin, Steven Muenster, Mary Abood, Khalid Benamar
Summary: This study found that blockade of GPR55 action in the periaqueductal gray can alleviate inflammatory pain, suggesting an important role of GPR55 in the descending pain modulatory system.
CANNABIS AND CANNABINOID RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Mary A. Lingerfelt, Pingwei Zhao, Haleli P. Sharir, Dow P. Hurst, Patricia H. Reggio, Mary E. Abood
Article
Pharmacology & Pharmacy
Elena Deliu, Margaret Sperow, Linda Console-Bram, Rhonda L. Carter, Douglas G. Tilley, Daniel J. Kalamarides, Lynn G. Kirby, G. Cristina Brailoiu, Eugen Brailoiu, Khalid Benamar, Mary E. Abood
MOLECULAR PHARMACOLOGY
(2015)
Article
Biochemistry & Molecular Biology
Pei-Yang Gao, Ya-Nan Ou, Yi-Ming Huang, Zhi-Bo Wang, Yan Fu, Ya-Hui Ma, Qiong-Yao Li, Li-Yun Ma, Rui-Ping Cui, Yin-Chu Mi, Lan Tan, Jin-Tai Yu
Summary: Liver function may play a role in the progression of Alzheimer's disease. The study found that as AD progressed, certain liver function markers increased while others decreased. The relationship between liver function and CSF AD biomarkers indicates a potential mediation effect on cognition.
JOURNAL OF NEUROCHEMISTRY
(2024)