Activation of GPR18 by cannabinoid compounds: a tale of biased agonism

A GPR18-based signalling system regulates IOP in murine eye

(2013) Meggie D. Caldwell et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

G-protein coupled receptor 18 (GPR18) in channel catfish: Expression analysis and efficacy as immunostimulant against Aeromonas hydrophila infection

(2013) Julia W. Pridgeon et al.   FISH & SHELLFISH IMMUNOLOGY

Distinct Roles of β-Arrestin 1 and β-Arrestin 2 in ORG27569-induced Biased Signaling and Internalization of the Cannabinoid Receptor 1 (CB1)

(2013) Kwang H. Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Activation of Cultured Neonatal Cardiomyocytes by PlasmalemmalVersusIntracellular G Protein-coupled Receptor 55

(2013) Justine Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antagonists for the Orphan G-Protein-Coupled Receptor GPR55 Based on a Coumarin Scaffold

(2013) Viktor Rempel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Modulation of the Endocannabinoid System: Vulnerability Factor and New Treatment Target for Stimulant Addiction

(2013) Stéphanie Olière et al.   Frontiers in Psychiatry

N -arachidonoyl glycine induces macrophage apoptosis via GPR18

(2012) Rina Takenouchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GPR18 in microglia: implications for the CNS and endocannabinoid system signalling

(2012) D McHugh   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid receptors: nomenclature and pharmacological principles

(2012) Linda Console-Bram et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The endocannabinoid system: an overview

(2012) Natalia Battista et al.   Frontiers in Behavioral Neuroscience

Δ9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells

(2011) Douglas McHugh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intracellular Cannabinoid Type 1 (CB1) Receptors Are Activated by Anandamide

(2011) G. Cristina Brailoiu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysophosphatidylinositol Causes Neurite Retraction via GPR55, G13 and RhoA in PC12 Cells

(2011) Yutaro Obara et al.   PLoS One

N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

(2010) Douglas McHugh et al.   BMC NEUROSCIENCE

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Quantitative expression profiling of G-protein-coupled receptors (GPCRs) in metastatic melanoma: the constitutively active orphan GPCR GPR18 as novel drug target

(2010) Y. Qin et al.   Pigment Cell & Melanoma Research

The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways

(2009) Heather B Bradshaw et al.   BMC BIOCHEMISTRY

Lipid G Protein-coupled Receptor Ligand Identification Using β-Arrestin PathHunter™ Assay

(2009) Hong Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anatomical Profiling of G Protein-Coupled Receptor Expression

(2008) Jean B. Regard et al.   CELL

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

(2008) J. E. Lauckner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA