Di-N-Methylation of Anti-Gram-Positive Aminoglycoside-Derived Membrane Disruptors Improves Antimicrobial Potency and Broadens Spectrum to Gram-Negative Bacteria

Amphiphilic Tobramycins with Immunomodulatory Properties

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Amphiphilic Tobramycin Analogues as Antibacterial and Antifungal Agents

(2015) Sanjib K. Shrestha et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tobramycin and Nebramine as Pseudo-oligosaccharide Scaffolds for the Development of Antimicrobial Cationic Amphiphiles

(2015) Yifat Berkov-Zrihen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structure–Activity Relationships for Antibacterial to Antifungal Conversion of Kanamycin to Amphiphilic Analogues

(2015) Marina Fosso et al.   JOURNAL OF ORGANIC CHEMISTRY

Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’

(2014) Tony Velkov et al.   ACS Chemical Biology

New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

(2014) Guillaume Sautrey et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Di-alkylated paromomycin derivatives: Targeting the membranes of Gram positive pathogens that cause skin infections

(2013) Yifat Berkov-Zrihen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Tuning the Antibacterial Activity of Amphiphilic Neamine Derivatives and Comparison to Paromamine Homologues

(2013) Louis Zimmermann et al.   JOURNAL OF MEDICINAL CHEMISTRY

6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes

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The Pseudomonas aeruginosa membranes: A target for a new amphiphilic aminoglycoside derivative?

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Antibacterial Activities of Aminoglycoside Antibiotics-Derived Cationic Amphiphiles. Polyol-Modified Neomycin B-, Kanamycin A-, Amikacin-, and Neamine-Based Amphiphiles with Potent Broad Spectrum Antibacterial Activity

(2010) Smritilekha Bera et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections

(2010) Julian G. Hurdle et al.   NATURE REVIEWS MICROBIOLOGY

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols