SAMHD1's protein expression profile in humans

Modulation of an Ectodomain Motif in the Influenza A Virus Neuraminidase Alters Tetherin Sensitivity and Results in Virus Attenuation In Vivo

(2014) Victor H. Leyva-Grado et al.   JOURNAL OF MOLECULAR BIOLOGY

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

(2014) Jeongmin Ryoo et al.   NATURE MEDICINE

p21 regulates the HIV-1 restriction factor SAMHD1

(2014) E. Pauls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reply to Pauls et al.: p21 is a master regulator of HIV replication in macrophages through dNTP synthesis block

(2014) A. Allouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into an X-traordinary viral protein

(2014) Torsten Schaller et al.   Frontiers in Microbiology

The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation

(2013) Tommy E. White et al.   Cell Host & Microbe

Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutières Syndrome and HIV-1 Restriction

(2013) Natalia Beloglazova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Restriction of HIV-1 Replication in Primary Macrophages by IL-12 and IL-18 through the Upregulation of SAMHD1

(2013) E. Pauls et al.   JOURNAL OF IMMUNOLOGY

SAMHD1 Restricts Herpes Simplex Virus 1 in Macrophages by Limiting DNA Replication

(2013) Eui Tae Kim et al.   JOURNAL OF VIROLOGY

Restriction of Virus Infection but Not Catalytic dNTPase Activity Is Regulated by Phosphorylation of SAMHD1

(2013) S. Welbourn et al.   JOURNAL OF VIROLOGY

Restriction of diverse retroviruses by SAMHD1

(2013) Thomas Gramberg et al.   Retrovirology

Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1

(2013) Alexandra Cribier et al.   Cell Reports

Host Factor SAMHD1 Restricts DNA Viruses in Non-Dividing Myeloid Cells

(2013) Joseph A. Hollenbaugh et al.   PLoS Pathogens

Tight Interplay among SAMHD1 Protein Level, Cellular dNTP Levels, and HIV-1 Proviral DNA Synthesis Kinetics in Human Primary Monocyte-derived Macrophages

(2012) Baek Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

(2012) Hichem Lahouassa et al.   NATURE IMMUNOLOGY

SAMHD1 restricts HIV-1 infection in resting CD4+ T cells

(2012) Hanna-Mari Baldauf et al.   NATURE MEDICINE

SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons

(2012) Corine St Gelais et al.   Retrovirology

Aicardi-Goutières Syndrome Gene and HIV-1 Restriction Factor SAMHD1 Is a dGTP-regulated Deoxynucleotide Triphosphohydrolase

(2011) Rebecca D. Powell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aicardi-Goutières Syndrome and Systemic Lupus Erythematosus (SLE) in a 12-Year-Old Boy With SAMHD1 Mutations

(2011) Georgia Ramantani et al.   JOURNAL OF CHILD NEUROLOGY

Budding Capability of the Influenza Virus Neuraminidase Can Be Modulated by Tetherin

(2011) M. A. Yondola et al.   JOURNAL OF VIROLOGY

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

(2011) David C. Goldstone et al.   NATURE

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humans

(2011) E. Erikson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Samhd1 changes our view of viral restriction

(2011) Nadine Laguette et al.   TRENDS IN IMMUNOLOGY

HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

(2011) S. Schmidt et al.   mBio

SAMHD1-Deficient CD14+ Cells from Individuals with Aicardi-Goutières Syndrome Are Highly Susceptible to HIV-1 Infection

(2011) André Berger et al.   PLoS Pathogens

Comparison of the Pathology Caused by H1N1, H5N1, and H3N2 Influenza Viruses

(2010) Jeannette Guarner et al.   ARCHIVES OF MEDICAL RESEARCH

Nucleic acid metabolism and systemic autoimmunity revisited

(2010) Min Ae Lee-Kirsch   ARTHRITIS AND RHEUMATISM

Cerebral arterial stenoses and stroke: novel features of Aicardi-Goutières syndrome caused by the Arg164X mutation in SAMHD1 are associated with altered cytokine expression

(2010) Holger Thiele et al.   HUMAN MUTATION

Chilblains as a Diagnostic Sign of Aicardi-Goutières Syndrome

(2010) G. M. H. Abdel-Salam et al.   NEUROPEDIATRICS

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

(2009) Y. J. Crow et al.   HUMAN MOLECULAR GENETICS

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

(2009) Gillian I Rice et al.   NATURE GENETICS

Dendritic cell-derived interferon-γ-induced protein mediates tumor necrosis factor-α stimulation of human lung fibroblasts

(2008) Wupeng Liao et al.   PROTEOMICS

Inhibition of G1P3 expression found in the differential display study on respiratory syncytial virus infection

(2008) Dong-chi Zhao et al.   Virology Journal

Pathogenetic mechanisms of severe acute respiratory syndrome

(2007) Yong Guo et al.   VIRUS RESEARCH