SAMHD1 restricts HIV-1 infection in resting CD4+ T cells

Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein

(2012) Nadine Laguette et al.   Cell Host & Microbe

The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx

(2012) Efrem S. Lim et al.   Cell Host & Microbe

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

(2012) Hichem Lahouassa et al.   NATURE IMMUNOLOGY

Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration

(2012) Hanna-Mari Tervo et al.   Retrovirology

Hiding in Plain Sight: How HIV Evades Innate Immune Responses

(2011) Nicolas Manel et al.   CELL

Aicardi-Goutières Syndrome Gene and HIV-1 Restriction Factor SAMHD1 Is a dGTP-regulated Deoxynucleotide Triphosphohydrolase

(2011) Rebecca D. Powell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Immunodeficiency Virus Type 1 Modified To Package Simian Immunodeficiency Virus Vpx Efficiently Infects Macrophages and Dendritic Cells

(2011) N. Sunseri et al.   JOURNAL OF VIROLOGY

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

(2011) David C. Goldstone et al.   NATURE

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

In vivo expression profile of the antiviral restriction factor and tumor-targeting antigen CD317/BST-2/HM1.24/tetherin in humans

(2011) E. Erikson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon

(2011) Thomas Pertel et al.   Retrovirology

SAMHD1-Deficient CD14+ Cells from Individuals with Aicardi-Goutières Syndrome Are Highly Susceptible to HIV-1 Infection

(2011) André Berger et al.   PLoS Pathogens

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

(2010) Gilad Doitsh et al.   CELL

Sustained LFA-1 cluster formation in the immune synapse requires the combined activities of L-plastin and calmodulin

(2010) Guido H. Wabnitz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cerebral arterial stenoses and stroke: novel features of Aicardi-Goutières syndrome caused by the Arg164X mutation in SAMHD1 are associated with altered cytokine expression

(2010) Holger Thiele et al.   HUMAN MUTATION

Interaction of Vpx and Apolipoprotein B mRNA-editing Catalytic Polypeptide 3 Family Member A (APOBEC3A) Correlates with Efficient Lentivirus Infection of Monocytes

(2010) André Berger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous CD317/Tetherin Limits Replication of HIV-1 and Murine Leukemia Virus in Rodent Cells and Is Resistant to Antagonists from Primate Viruses

(2010) C. Goffinet et al.   JOURNAL OF VIROLOGY

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

(2010) Nicolas Manel et al.   NATURE

HIV-1 Antagonism of CD317 Is Species Specific and Involves Vpu-Mediated Proteasomal Degradation of the Restriction Factor

(2009) Christine Goffinet et al.   Cell Host & Microbe

Human Immunodeficiency Virus Integrates Directly into Naive Resting CD4+ T Cells but Enters Naive Cells Less Efficiently than Memory Cells

(2009) J. Dai et al.   JOURNAL OF VIROLOGY

The Human Immunodeficiency Virus Type 2 Vpx Protein Usurps the CUL4A-DDB1DCAF1 Ubiquitin Ligase To Overcome a Postentry Block in Macrophage Infection

(2009) A. Bergamaschi et al.   JOURNAL OF VIROLOGY

Evidence for an Activation Domain at the Amino Terminus of Simian Immunodeficiency Virus Vpx

(2009) T. Gramberg et al.   JOURNAL OF VIROLOGY

APOBEC3G-Depleted Resting CD4+ T Cells Remain Refractory to HIV1 Infection

(2009) Francesca R. Santoni de Sio et al.   PLoS One

Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec

(2009) Alessia Ruggieri et al.   Retrovirology

HIV Envelope-CXCR4 Signaling Activates Cofilin to Overcome Cortical Actin Restriction in Resting CD4 T Cells

(2008) Alyson Yoder et al.   CELL

SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors

(2008) G Berger et al.   GENE THERAPY

Characterization of Simian Immunodeficiency Virus SIVSM/Human Immunodeficiency Virus Type 2 Vpx Function in Human Myeloid Cells

(2008) C. Goujon et al.   JOURNAL OF VIROLOGY

Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density

(2008) Silvia Geuenich et al.   Retrovirology

Primate Lentiviral Vpx Commandeers DDB1 to Counteract a Macrophage Restriction

(2008) Natalia Sharova et al.   PLoS Pathogens

Lentiviral Vpx Accessory Factor Targets VprBP/DCAF1 Substrate Adaptor for Cullin 4 E3 Ubiquitin Ligase to Enable Macrophage Infection

(2008) Smita Srivastava et al.   PLoS Pathogens