“Click” reactions: a versatile toolbox for the synthesis of peptide-conjugates

Defined Polymer-Peptide Conjugates to Form Cell-Instructive starPEG-Heparin Matrices In Situ

(2013) Mikhail V. Tsurkan et al.   ADVANCED MATERIALS

On-chip Enrichment and Analysis of Peptide Subsets Using a Maleimide-functionalized Fluorous Affinity Biochip and Nanostructure Initiator Mass Spectrometry

(2013) J. Li et al.   ANALYTICAL CHEMISTRY

Spatially Controlled Surface Immobilization of Nonmodified Peptides

(2013) Thomas Pauloehrl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Peptide Lipidation through Thiol-Ene Coupling Enables Rapid Synthesis and Evaluation of Self-Adjuvanting Vaccine Candidates

(2013) Tom H. Wright et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Relative Performance of Alkynes in Copper-Catalyzed Azide–Alkyne Cycloaddition

(2013) Alexander A. Kislukhin et al.   BIOCONJUGATE CHEMISTRY

Facile Fabrication of “Dual Click” One- and Two-Dimensional Orthogonal Peptide Concentration Gradients

(2013) Yanrui Ma et al.   BIOMACROMOLECULES

Cascading “Triclick” Functionalization of Poly(caprolactone) Thin Films Quantified via a Quartz Crystal Microbalance

(2013) Fei Lin et al.   BIOMACROMOLECULES

Valency-Dependent Affinity of Bioactive Hydroxyapatite-Binding Dendrons

(2013) Wen Tang et al.   BIOMACROMOLECULES

Synthetically Tractable Click Hydrogels for Three-Dimensional Cell Culture Formed Using Tetrazine–Norbornene Chemistry

(2013) Daniel L. Alge et al.   BIOMACROMOLECULES

Peptide-Functionalized Oxime Hydrogels with Tunable Mechanical Properties and Gelation Behavior

(2013) Fei Lin et al.   BIOMACROMOLECULES

Thiol-addition reactions and their applications in thiol recognition

(2013) Caixia Yin et al.   CHEMICAL SOCIETY REVIEWS

The Thiol-Michael Addition Click Reaction: A Powerful and Widely Used Tool in Materials Chemistry

(2013) Devatha P. Nair et al.   CHEMISTRY OF MATERIALS

Nanoparticles under the Light: Click Functionalization by Photochemical Thiol-yne Reaction, Towards Double Click Functionalization

(2013) Paul Demay-Drouhard et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Carbohydrate-Functionalised Sequence-Defined Oligo(amidoamine)s by Photochemical ThiolEne Coupling in a Continuous Flow Reactor

(2013) Felix Wojcik et al.   CHEMISTRY-A EUROPEAN JOURNAL

Native Chemical Ligation,Thiol–Ene Click: A Methodology for the Synthesis of Functionalized Peptides

(2013) Lyn Markey et al.   JOURNAL OF ORGANIC CHEMISTRY

Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High-Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography

(2013) Bobo Dang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Minimal Peptide Motif for Non-covalent Peptide–Heparin Hydrogels

(2013) Robert Wieduwild et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Postelectrospinning “Click” Modification of Degradable Amino Acid-Based Poly(ester urea) Nanofibers

(2013) Fei Lin et al.   MACROMOLECULES

GRGDS-Functionalized Poly(lactide)-graft-poly(ethylene glycol) Copolymers: Combining Thiol–Ene Chemistry with Staudinger Ligation

(2013) Dorothee E. Borchmann et al.   MACROMOLECULES

Thiol–yne radical reaction mediated site-specific protein labeling via genetic incorporation of an alkynyl-l-lysine analogue

(2013) Yiming Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Modular Ligation of Thioamide Functional Peptides onto Solid Cellulose Substrates

(2012) Thomas Tischer et al.   ADVANCED FUNCTIONAL MATERIALS

(Bio)Molecular Surface Patterning by Phototriggered Oxime Ligation

(2012) Thomas Pauloehrl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Copper-Free Click Chemistry In Vivo for Tumor-Targeted Delivery of Nanoparticles

(2012) Heebeom Koo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Scaffolds Using Multiple Orthogonal Conjugations: Applications in Chemical Biology and Drug Discovery

(2012) David M. Beal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amino Acids for Diels-Alder Reactions in Living Cells

(2012) Tilman Plass et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Heterobifunctional Protein Fusions Using Copper-Free Click Chemistry and the Aldehyde Tag

(2012) Jason E. Hudak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocompatible Silicon Surfaces through Orthogonal Click Chemistries and a High Affinity Silicon Oxide Binding Peptide

(2012) Rayk Hassert et al.   BIOCONJUGATE CHEMISTRY

Preventing Thiol-Yne Addition Improves the Specificity of Strain-Promoted Azide–Alkyne Cycloaddition

(2012) Remon van Geel et al.   BIOCONJUGATE CHEMISTRY

Specific Labeling of Zinc Finger Proteins using Noncanonical Amino Acids and Copper-Free Click Chemistry

(2012) Younghoon Kim et al.   BIOCONJUGATE CHEMISTRY

Application of Strain-Promoted Azide–Alkyne Cycloaddition and Tetrazine Ligation to Targeted Fc-Drug Conjugates

(2012) Joshua D. Thomas et al.   BIOCONJUGATE CHEMISTRY

F-18 Labeling Protocol of Peptides Based on Chemically Orthogonal Strain-Promoted Cycloaddition under Physiologically Friendly Reaction Conditions

(2012) Kalme Sachin et al.   BIOCONJUGATE CHEMISTRY

Polyvalent Side Chain Peptide–Synthetic Polymer Conjugates as HIV-1 Entry Inhibitors

(2012) Maarten Danial et al.   BIOMACROMOLECULES

Biocompatible Hydrogels by Oxime Click Chemistry

(2012) Gregory N. Grover et al.   BIOMACROMOLECULES

Cross-Linking and Degradation of Step-Growth Hydrogels Formed by Thiol–Ene Photoclick Chemistry

(2012) Han Shih et al.   BIOMACROMOLECULES

Efficient γ-amino-proline-derived cell penetrating peptide–superparamagnetic iron oxide nanoparticle conjugates via aniline-catalyzed oxime chemistry as bimodal imaging nanoagents

(2012) Silvia Cavalli et al.   CHEMICAL COMMUNICATIONS

Click–click chemistry on a peptidic scaffold for easy access to tetrameric DNA structures

(2012) Romaric Bonnet et al.   CHEMICAL COMMUNICATIONS

Vapor-based synthesis of maleimide-functionalized coating for biointerface engineering

(2012) Meng-Yu Tsai et al.   CHEMICAL COMMUNICATIONS

Synthesis of Multivalent Neoglyconjugates of MUC1 by the Conjugation of Carbohydrate-Centered, Triazole-Linked Glycoclusters to MUC1 Peptides Using Click Chemistry

(2012) Dong Jun Lee et al.   JOURNAL OF ORGANIC CHEMISTRY

Post-Assembly Derivatization of Electrospun Nanofibers via Strain-Promoted Azide Alkyne Cycloaddition

(2012) Jukuan Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorophore Targeting to Cellular Proteins via Enzyme-Mediated Azide Ligation and Strain-Promoted Cycloaddition

(2012) Jennifer Z. Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiol–Ene Click Chemistry: Computational and Kinetic Analysis of the Influence of Alkene Functionality

(2012) Brian H. Northrop et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strain-Promoted “Click” Modification of a Mesoporous Metal–Organic Framework

(2012) Chong Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Micropatterning of Functional Conductive Polymers with Multiple Surface Chemistries in Register

(2012) Johan U. Lind et al.   LANGMUIR

Rate Determination of Azide Click Reactions onto Alkyne Polymer Brush Scaffolds: A Comparison of Conventional and Catalyst-Free Cycloadditions for Tunable Surface Modification

(2012) Sara V. Orski et al.   LANGMUIR

Direct Characterization of Native Chemical Ligation of Peptides on Silicon Nanowires

(2012) Nabil Dendane et al.   LANGMUIR

A Proline-Based Phosphine Template for Staudinger Ligation

(2012) Chung-Min Park et al.   ORGANIC LETTERS

Strain-Promoted Catalyst-Free Click Chemistry for Rapid Construction of 64Cu-Labeled PET Imaging Probes

(2012) Kai Chen et al.   ACS Medicinal Chemistry Letters

Bioorthogonal Click Chemistry: An Indispensable Tool to Create Multifaceted Cell Culture Scaffolds

(2012) Malar A. Azagarsamy et al.   ACS Macro Letters

From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions

(2011) Ellen M. Sletten et al.   ACCOUNTS OF CHEMICAL RESEARCH

Biomedical Applications of Tetrazine Cycloadditions

(2011) Neal K. Devaraj et al.   ACCOUNTS OF CHEMICAL RESEARCH

Evaluation of Multivalent, Functional Polymeric Nanoparticles for Imaging Applications

(2011) Monica Shokeen et al.   ACS Nano

Surface Functionalization by Strain-Promoted Alkyne-Azide Click Reactions

(2011) Radostina Manova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Access to Biomolecular Assemblies through One-Pot Triple Orthogonal Chemoselective Ligations

(2011) Mathieu Galibert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reliable and Efficient Procedures for the Conjugation of Biomolecules through Huisgen Azide-Alkyne Cycloadditions

(2011) Enrique Lallana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Staudinger Ligation as a Method for Bioconjugation

(2011) Sander S. van Berkel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study

(2011) Christen Besanceney-Webler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dendrimer Display of Tumor-Homing Peptides

(2011) Edith H. M. Lempens et al.   BIOCONJUGATE CHEMISTRY

Side-Chain Peptide-Synthetic Polymer Conjugates via Tandem “Ester-Amide/Thiol–Ene” Post-Polymerization Modification of Poly(pentafluorophenyl methacrylate) Obtained Using ATRP

(2011) Nikhil K. Singha et al.   BIOMACROMOLECULES

Antibacterial Surfaces Based on Polymer Brushes: Investigation on the Influence of Brush Properties on Antimicrobial Peptide Immobilization and Antimicrobial Activity

(2011) Guangzheng Gao et al.   BIOMACROMOLECULES

Multi-molecule reaction of serum albumin can occur through thiol-yne coupling

(2011) Mauro Lo Conte et al.   CHEMICAL COMMUNICATIONS

Modular synthesis of supramolecular ureidopyrimidinone–peptide conjugates using an oxime ligation strategy

(2011) Roxanne E. Kieltyka et al.   CHEMICAL COMMUNICATIONS

Recent applications of thiol–ene coupling as a click process for glycoconjugation

(2011) Alessandro Dondoni et al.   CHEMICAL SOCIETY REVIEWS

Click to Join Peptides/Proteins Together

(2011) Xuechen Li   Chemistry-An Asian Journal

On-Demand Electrochemical Activation of the Click Reaction on Self-Assembled Monolayers on Gold Presenting Masked Acetylene Groups

(2011) Inseong Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Native Chemical Ligation of Hydrolysis-Resistant 3′-Peptidyl–tRNA Mimics

(2011) Anna-Skrollan Geiermann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From Phage Display to Dendrimer Display: Insights into Multivalent Binding

(2011) Maartje M. C. Bastings et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combination of Integrin-Binding Peptide and Growth Factor Promotes Cell Adhesion on Electron-Beam-Fabricated Patterns

(2011) Christopher M. Kolodziej et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of an NDPK Phosphocarrier Domain Peptide Containing a Novel Triazolylalanine Analogue of Phosphohistidine Using Click Chemistry

(2011) Sung Hyun Yang et al.   ORGANIC LETTERS

Thiol-Yne Chemistry: A Powerful Tool for Creating Highly Functional Materials

(2010) Richard Hoogenboom   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vivo Chemistry for Pretargeted Tumor Imaging in Live Mice

(2010) Raffaella Rossin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Surface Functionalization Using Catalyst-Free Azide−Alkyne Cycloaddition

(2010) Alexander Kuzmin et al.   BIOCONJUGATE CHEMISTRY

Copper-Free Click Chemistry for Highly Luminescent Quantum Dot Conjugates: Application toin VivoMetabolic Imaging

(2010) Aude Bernardin et al.   BIOCONJUGATE CHEMISTRY

Solid-Phase Synthesis of PEGylated Lipopeptides Using Click Chemistry

(2010) Rasmus I. Jølck et al.   BIOCONJUGATE CHEMISTRY

Peptide-Modified “Smart” Hydrogels and Genetically Engineered Stem Cells for Skeletal Tissue Engineering

(2010) Shai Garty et al.   BIOMACROMOLECULES

Synthesis and Characterization of Enzymatically Biodegradable PEG and Peptide-Based Hydrogels Prepared by Click Chemistry

(2010) Maarten van Dijk et al.   BIOMACROMOLECULES

Biofunctionalization of electrospun PCL-based scaffolds with perlecan domain IV peptide to create a 3-D pharmacokinetic cancer model

(2010) Olga Hartman et al.   BIOMATERIALS

Native chemical ligation in the synthesis of internally modified oligonucleotide-peptide conjugates

(2010) Franziska Diezmann et al.   BIOPOLYMERS

Invited reviewnative chemical ligation applied to the synthesis and bioengineering of circular peptides and proteins

(2010) Richard J. Clark et al.   BIOPOLYMERS

Multimerization of cRGD Peptides by Click Chemistry: Synthetic Strategies, Chemical Limitations, and Influence on Biological Properties

(2010) Carmen Wängler  et al.   CHEMBIOCHEM

Two-Step Labeling of Endogenous Enzymatic Activities by Diels-Alder Ligation

(2010) Lianne I. Willems et al.   CHEMBIOCHEM

Bioresponsive peptide–inorganic hybrid nanomaterials

(2010) Daniel Aili et al.   CHEMICAL SOCIETY REVIEWS

Stimulus responsive peptide based materials

(2010) Dennis W. P. M. Löwik et al.   CHEMICAL SOCIETY REVIEWS

More than just bare scaffolds: towards multi-component and decorated fibrous biomaterials

(2010) Derek N. Woolfson et al.   CHEMICAL SOCIETY REVIEWS

Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture

(2010) Cole A. DeForest et al.   CHEMISTRY OF MATERIALS

Surface Modification of Polymeric Micelles by Strain-Promoted Alkyne-Azide Cycloadditions

(2010) Jun Guo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Thiol-yne click chemistry: A powerful and versatile methodology for materials synthesis

(2010) Andrew B. Lowe et al.   JOURNAL OF MATERIALS CHEMISTRY

Oligonucleotide Sequential Bis-Conjugation via Click−Oxime and Click−Huisgen Procedures

(2010) Albert Meyer et al.   JOURNAL OF ORGANIC CHEMISTRY

Photoinduced Addition of Glycosyl Thiols to Alkynyl Peptides: Use of Free-Radical Thiol−Yne Coupling for Post-Translational Double-Glycosylation of Peptides

(2010) Mauro Lo Conte et al.   JOURNAL OF ORGANIC CHEMISTRY

An Insight into the Radical Thiol/Yne Coupling: The Emergence of Arylalkyne-Tagged Sugars for the Direct Photoinduced Glycosylation of Cysteine-Containing Peptides

(2010) Matteo Minozzi et al.   JOURNAL OF ORGANIC CHEMISTRY

Efficient synthesis of an (aminooxy) acetylated-somatostatin derivative using (aminooxy)acetic acid as a ‘carbonyl capture’ reagent

(2010) Gábor Mezö et al.   JOURNAL OF PEPTIDE SCIENCE

Strain-Promoted Alkyne Azide Cycloaddition for the Functionalization of Poly(amide)-Based Dendrons and Dendrimers

(2010) Cátia Ornelas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High Density Orthogonal Surface Immobilization via Photoactivated Copper-Free Click Chemistry

(2010) Sara V. Orski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting of Cancer Cells Using Click-Functionalized Polymer Capsules

(2010) Marloes M. J. Kamphuis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocompatible Copper(I) Catalysts for in Vivo Imaging of Glycans

(2010) David Soriano del Amo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemoselective Immobilization of Peptides on Abiotic and Cell Surfaces at Controlled Densities

(2010) Venkata R. Krishnamurthy et al.   LANGMUIR

Complex Surface Concentration Gradients by Stenciled ”Electro Click Chemistry”

(2010) Thomas S. Hansen et al.   LANGMUIR

A Comparison of Triazole-forming Bioconjugation Techniques for Constructing Comb-Shaped Peptide-Polymer Bioconjugates

(2010) Luiz A. Canalle et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Nucleophile-Initiated Thiol-Michael Reactions: Effect of Organocatalyst, Thiol, and Ene

(2010) Justin W. Chan et al.   MACROMOLECULES

Alkyne–azide click reaction catalyzed by metallic copper under ultrasound

(2010) Pedro Cintas et al.   Nature Protocols

Application of click–click chemistry to the synthesis of new multivalent RGD conjugates

(2010) Mathieu Galibert et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization

(2009) Benjamin D. Fairbanks et al.   ADVANCED MATERIALS

Modular Peptide Growth Factors for Substrate-Mediated Stem Cell Differentiation

(2009) Jae Sam Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thiyl Glycosylation of Olefinic Proteins: S-Linked Glycoconjugate Synthesis

(2009) Nicola Floyd et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrafast Click Conjugation of Macromolecular Building Blocks at Ambient Temperature

(2009) Andrew J. Inglis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Approach to Well-Defined Biomolecular Assemblies by Orthogonal Chemoselective Ligations

(2009) Mathieu Galibert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis and Optimization of Copper-Catalyzed Azide–Alkyne Cycloaddition for Bioconjugation

(2009) Vu Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile Conjugation of Octreotide to Dendrimers by Cycloaddition (“Click”) Chemistry to Yield High-Affinity Multivalent Cyclic Peptide Dendrimers

(2009) Cheng-Bin Yim et al.   BIOCONJUGATE CHEMISTRY

Hydrogels Cross-Linked by Native Chemical Ligation

(2009) Bi-Huang Hu et al.   BIOMACROMOLECULES

Preparation of Biomolecule Microstructures and Microarrays by Thiol-ene Photoimmobilization

(2009) Dirk Weinrich et al.   CHEMBIOCHEM

Phosphine-mediated one-pot thiol–ene “click” approach to polymer–protein conjugates

(2009) Mathew W. Jones et al.   CHEMICAL COMMUNICATIONS

Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition

(2009) Marjoke F. Debets et al.   CHEMICAL COMMUNICATIONS

Risks of Copper and Iron Toxicity during Aging in Humans

(2009) George J. Brewer   CHEMICAL RESEARCH IN TOXICOLOGY

Amino Acid-Protecting Groups

(2009) Albert Isidro-Llobet et al.   CHEMICAL REVIEWS

Cu(I)-Catalyzed Huisgen Azide−Alkyne 1,3-Dipolar Cycloaddition Reaction in Nucleoside, Nucleotide, and Oligonucleotide Chemistry

(2009) Franck Amblard et al.   CHEMICAL REVIEWS

Marrying click chemistry with polymerization: expanding the scope of polymeric materials

(2009) Patricia L. Golas et al.   CHEMICAL SOCIETY REVIEWS

A New Ligation Strategy for Peptide and Protein Glycosylation: Photoinduced Thiol-Ene Coupling

(2009) Alessandro Dondoni et al.   CHEMISTRY-A EUROPEAN JOURNAL

Inverse-electron-demand Diels-Alder reaction as a highly efficient chemoselective ligation procedure: Synthesis and function of a BioShuttle for temozolomide transport into prostate cancer cells

(2009) Rüdiger Pipkorn et al.   JOURNAL OF PEPTIDE SCIENCE

Azide reduction during peptide cleavage from solid support—the choice of thioscavenger?

(2009) Philipp E. Schneggenburger et al.   JOURNAL OF PEPTIDE SCIENCE

Biomimetic Synthesis of Lispro Insulin via a Chemically Synthesized “Mini-Proinsulin” Prepared by Oxime-Forming Ligation

(2009) Youhei Sohma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-Affinity Peptide-Based Collagen Targeting Using Synthetic Phage Mimics: From Phage Display to Dendrimer Display

(2009) Brett A. Helms et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Directed Assembly of PEGylated-Peptide Coatings for Infection-Resistant Titanium Metal

(2009) Xiaojuan Khoo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Collagen Targeting Using Protein-Functionalized Micelles: The Strength of Multiple Weak Interactions

(2009) Sanne W. A. Reulen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Using “Click” Chemistry to Prepare SAM Substrates to Study Stem Cell Adhesion

(2009) Gregory A. Hudalla et al.   LANGMUIR

Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments

(2009) Cole A. DeForest et al.   NATURE MATERIALS

Synthesis of Fish Antifreeze Neoglycopeptides Using Microwave-Assisted “Click Chemistry”

(2009) Nicole Miller et al.   ORGANIC LETTERS

A One-Pot Approach to Neoglycopeptides using Orthogonal Native Chemical Ligation and Click Chemistry

(2009) Dong Jun Lee et al.   ORGANIC LETTERS

Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide–alkyne “click” chemistry☆

(2008) J LUTZ et al.   ADVANCED DRUG DELIVERY REVIEWS

Chemoselective Ligation and Modification Strategies for Peptides and Proteins

(2008) Christian P. R. Hackenberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective Peptide Cyclization by Traceless Staudinger Ligation

(2008) Rolf Kleineweischede et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photochemical Surface Patterning by the Thiol-Ene Reaction

(2008) Pascal Jonkheijm et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Protein Mimics with Nonlinear Backbone Topology by a Combined Recombinant, Enzymatic, and Chemical Synthesis Strategy

(2008) Stephan Pritz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions

(2008) Xinghai Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dual Labeling of Biomolecules by Using Click Chemistry: A Sequential Approach

(2008) Péter Kele et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Signal Transduction of Hyaluronic Acid−Peptide Conjugate for Formyl Peptide Receptor Like 1 Receptor

(2008) Eun Ju Oh et al.   BIOCONJUGATE CHEMISTRY

In VivoTumor Cell Targeting with “Click” Nanoparticles

(2008) Geoffrey von Maltzahn et al.   BIOCONJUGATE CHEMISTRY

Rapid Oxime and Hydrazone Ligations with Aromatic Aldehydes for Biomolecular Labeling

(2008) Anouk Dirksen et al.   BIOCONJUGATE CHEMISTRY

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

(2008) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

Three-Dimensional Biochemical Patterning of Click-Based Composite Hydrogels via Thiolene Photopolymerization

(2008) Brian D. Polizzotti et al.   BIOMACROMOLECULES

Biodegradable poly(ethylene glycol)–peptide hydrogels with well-defined structure and properties for cell delivery

(2008) Shao Qiong Liu et al.   BIOMATERIALS

Electrochemically Protected Copper(I)-Catalyzed Azide-Alkyne Cycloaddition

(2008) Vu Hong et al.   CHEMBIOCHEM

Total chemical synthesis of proteins

(2008) Stephen B. H. Kent   CHEMICAL SOCIETY REVIEWS

Racemization-Free Synthesis of S-Alkylated Cysteines via Thiol-ene Reaction

(2008) Gemma Triola et al.   JOURNAL OF ORGANIC CHEMISTRY

Selective Functionalization of a Genetically Encoded Alkene-Containing Protein via “Photoclick Chemistry” in Bacterial Cells

(2008) Wenjiao Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxo-ester Mediated Native Chemical Ligation: Concept and Applications

(2008) Qian Wan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sugar-Assisted Glycopeptide Ligation with Complex Oligosaccharides: Scope and Limitations

(2008) Clay S. Bennett et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Interfacial Oxime Reaction To Immobilize Ligands and Cells in Patterns and Gradients to Photoactive Surfaces

(2008) Sungjin Park et al.   LANGMUIR

In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish

(2008) S. T. Laughlin et al.   SCIENCE