标题
Biological metals and metal-targeting compounds in major neurodegenerative diseases
作者
关键词
-
出版物
CHEMICAL SOCIETY REVIEWS
Volume 43, Issue 19, Pages 6727-6749
出版商
Royal Society of Chemistry (RSC)
发表日期
2014-08-07
DOI
10.1039/c4cs00138a
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Increased Levels of Magnetic Iron Compounds in Alzheimer's Disease
- (2017) Quentin Pankhurst et al. JOURNAL OF ALZHEIMERS DISEASE
- Clioquinol Decreases Amyloid-β Burden and Reduces Working Memory Impairment in a Transgenic Mouse Model of Alzheimer's Disease
- (2017) Cristina Grossi et al. JOURNAL OF ALZHEIMERS DISEASE
- Deficiency of the Copper Chaperone for Superoxide Dismutase Increases Amyloid-β Production
- (2017) Emma H. Gray et al. JOURNAL OF ALZHEIMERS DISEASE
- PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses
- (2017) Noel G. Faux et al. JOURNAL OF ALZHEIMERS DISEASE
- Bis (thiosemicarbazonato) Cu-64 Complexes for Positron Emission Tomography Imaging of Alzheimer's Disease
- (2017) Michelle T. Fodero-Tavoletti et al. JOURNAL OF ALZHEIMERS DISEASE
- Metal Ions and Intrinsically Disordered Proteins and Peptides: From Cu/Zn Amyloid-β to General Principles
- (2014) Peter Faller et al. ACCOUNTS OF CHEMICAL RESEARCH
- The Bioinorganic Chemistry of Apoptosis: Potential Inhibitory Zinc Binding Sites in Caspase-3
- (2014) A. Gerard Daniel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Value of serum nonceruloplasmin copper for prediction of mild cognitive impairment conversion to Alzheimer disease
- (2014) Rosanna Squitti et al. ANNALS OF NEUROLOGY
- sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin
- (2014) R. C. McCarthy et al. EMBO REPORTS
- Iron deposits in post-mortem brains of patients with neurodegenerative and cerebrovascular diseases: a semi-quantitative 7.0 T magnetic resonance imaging study
- (2014) J. L. De Reuck et al. EUROPEAN JOURNAL OF NEUROLOGY
- Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction
- (2014) Jin-Sung Park et al. HUMAN MOLECULAR GENETICS
- Site-Specific Copper-Catalyzed Oxidation of α-Synuclein: Tightening the Link between Metal Binding and Protein Oxidative Damage in Parkinson’s Disease
- (2014) Marco C. Miotto et al. INORGANIC CHEMISTRY
- Phosphorylation of Amyloid Precursor Protein at Threonine 668 Is Essential for Its Copper-responsive Trafficking in SH-SY5Y Neuroblastoma Cells
- (2014) Karla M. Acevedo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Imbalance of iron influx and efflux causes brain iron accumulation over time in the healthy adult rat
- (2014) Jie-Hua Chen et al. Metallomics
- Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasis
- (2014) B. Elise Needham et al. Metallomics
- An anemia of Alzheimer's disease
- (2014) N G Faux et al. MOLECULAR PSYCHIATRY
- Copper is required for oncogenic BRAF signalling and tumorigenesis
- (2014) Donita C. Brady et al. NATURE
- Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease
- (2014) Javier Becerril-Ortega et al. NEUROBIOLOGY OF AGING
- An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta
- (2014) Dominic J. Hare et al. Chemical Science
- Aging results in copper accumulations in glial fibrillary acidic protein-positive cells in the subventricular zone
- (2013) Yulia Pushkar et al. AGING CELL
- Cortical phase changes in Alzheimer's disease at 7T MRI: A novel imaging marker
- (2013) Sanneke van Rooden et al. Alzheimers & Dementia
- The Catalytically Active Copper-Amyloid-Beta State: Coordination Site Responsible for Reactive Oxygen Species Production
- (2013) Laure-Estelle Cassagnes et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease
- (2013) David Devos et al. ANTIOXIDANTS & REDOX SIGNALING
- Biophysical Studies of the Amyloid β-Peptide: Interactions with Metal Ions and Small Molecules
- (2013) Sebastian Wärmländer et al. CHEMBIOCHEM
- Efficacy and Toxicity of Clioquinol Treatment and A-beta42 Inoculation in the APP/PSI Mouse Model of Alzheimer’s Disease
- (2013) Yi-Hong Zhang et al. Current Alzheimer Research
- SOD1 Aggregation and ALS: Role of Metallation States and Disulfide Status
- (2013) Yuewei Sheng et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Copper and Heme-Mediated Abeta Toxicity: Redox Chemistry, Abeta Oxidations and Anti-ROS Compounds
- (2013) Stefan Chassaing et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Loss of iron triggers PINK1/Parkin-independent mitophagy
- (2013) George F G Allen et al. EMBO REPORTS
- Chronic intranasal deferoxamine ameliorates motor defects and pathology in the α-synuclein rAAV Parkinson's model
- (2013) Fabia Febbraro et al. EXPERIMENTAL NEUROLOGY
- Zn2+ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation
- (2013) Taiji Tsunemi et al. HUMAN MOLECULAR GENETICS
- Role of Metal Ions in the Self-assembly of the Alzheimer’s Amyloid-β Peptide
- (2013) Peter Faller et al. INORGANIC CHEMISTRY
- Quantitative assessment of subcortical atrophy and iron content in progressive supranuclear palsy and parkinsonian variant of multiple system atrophy
- (2013) Jae-Hyeok Lee et al. JOURNAL OF NEUROLOGY
- Synaptic Zn2+ Inhibits Neurotransmitter Release by Promoting Endocannabinoid Synthesis
- (2013) T. Perez-Rosello et al. JOURNAL OF NEUROSCIENCE
- Iron levels in the human brain: A post-mortem study of anatomical region differences and age-related changes
- (2013) Patrícia Ramos et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- High precision isotope measurements reveal poor control of copper metabolism in Parkinsonism
- (2013) F. Larner et al. Metallomics
- SOD1 as a Molecular Switch for Initiating the Homeostatic ER Stress Response under Zinc Deficiency
- (2013) Kengo Homma et al. MOLECULAR CELL
- The changing scene of amyotrophic lateral sclerosis
- (2013) Wim Robberecht et al. NATURE REVIEWS NEUROSCIENCE
- Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease–like symptoms
- (2013) Minglin Lang et al. NEUROBIOLOGY OF AGING
- Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation
- (2013) Ângela C. Crespo et al. NEUROBIOLOGY OF AGING
- Dysregulation of intracellular copper homeostasis is common to transgenic mice expressing human mutant superoxide dismutase-1s regardless of their copper-binding abilities
- (2013) Eiichi Tokuda et al. NEUROBIOLOGY OF DISEASE
- Motor phenotype and magnetic resonance measures of basal ganglia iron levels in Parkinson's disease
- (2013) Nico Bunzeck et al. PARKINSONISM & RELATED DISORDERS
- Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine
- (2013) Jianfang Chen et al. PLoS One
- Convergent Ca2+and Zn2+signaling regulates apoptotic Kv2.1 K+currents
- (2013) Meghan C. McCord et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding
- (2013) G. Xiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance
- (2013) Itender Singh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Copper prevents amyloid-β1–42 from forming amyloid fibrils under near-physiological conditions in vitro
- (2013) Matthew Mold et al. Scientific Reports
- Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis
- (2013) Jonathon Telianidis et al. Frontiers in Aging Neuroscience
- Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis
- (2013) Erin J. McAllum et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer’s disease
- (2013) Animesh Raha et al. Acta Neuropathologica Communications
- Cu(II) Affinity for the Alzheimer’s Peptide: Tyrosine Fluorescence Studies Revisited
- (2012) Bruno Alies et al. ANALYTICAL CHEMISTRY
- A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants
- (2012) Takao Fujisawa et al. ANNALS OF NEUROLOGY
- Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease
- (2012) Scott Ayton et al. ANNALS OF NEUROLOGY
- The Novel Multi-Target Iron Chelating-Radical Scavenging Compound M30 Possesses Beneficial Effects on Major Hallmarks of Alzheimer's Disease
- (2012) Lana Kupershmidt et al. ANTIOXIDANTS & REDOX SIGNALING
- Alterations in Brain Transition Metals in Huntington Disease
- (2012) H. Diana Rosas et al. ARCHIVES OF NEUROLOGY
- The Elevated Copper Binding Strength of Amyloid-β Aggregates Allows the Sequestration of Copper from Albumin: A Pathway to Accumulation of Copper in Senile Plaques
- (2012) Dianlu Jiang et al. BIOCHEMISTRY
- Analogues of oxy-heme Aβ: reactive intermediates relevant to Alzheimer's disease
- (2012) Manas Seal et al. CHEMICAL COMMUNICATIONS
- Werner coordination chemistry and neurodegeneration
- (2012) Maria A. Telpoukhovskaia et al. CHEMICAL SOCIETY REVIEWS
- Inhibition of Cu-Amyloid-β by using Bifunctional Peptides with β-Sheet Breaker and Chelator Moieties
- (2012) Madeleine Jensen et al. CHEMISTRY-A EUROPEAN JOURNAL
- Bioinorganic chemistry of copper coordination to alpha-synuclein: Relevance to Parkinson's disease
- (2012) Andrés Binolfi et al. COORDINATION CHEMISTRY REVIEWS
- Metal binding sites in amyloid oligomers: Complexes and mechanisms
- (2012) Yifat Miller et al. COORDINATION CHEMISTRY REVIEWS
- The art of building multifunctional metal-binding agents from basic molecular scaffolds for the potential application in neurodegenerative diseases
- (2012) Cristina Rodríguez-Rodríguez et al. COORDINATION CHEMISTRY REVIEWS
- Interaction of amyloid β peptides with redox active heme cofactor: Relevance to Alzheimer's disease
- (2012) Debajyoti Pramanik et al. COORDINATION CHEMISTRY REVIEWS
- Zn2+-Aβ40 Complexes Form Metastable Quasi-spherical Oligomers That Are Cytotoxic to Cultured Hippocampal Neurons
- (2012) Inna Solomonov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multitarget-Directed Benzylideneindanone Derivatives: Anti-β-Amyloid (Aβ) Aggregation, Antioxidant, Metal Chelation, and Monoamine Oxidase B (MAO-B) Inhibition Properties against Alzheimer’s Disease
- (2012) Ling Huang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain
- (2012) Sven O. Dahms et al. JOURNAL OF MOLECULAR BIOLOGY
- Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ42 Peptide
- (2012) Anuj K. Sharma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Multi-target, Neuroprotective and Neurorestorative M30 Improves Cognitive Impairment and Reduces Alzheimer's-Like Neuropathology and Age-Related Alterations in Mice
- (2012) Lana Kupershmidt et al. MOLECULAR NEUROBIOLOGY
- Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer’s disease neuropathology
- (2012) Nicole L Bjorklund et al. Molecular Neurodegeneration
- Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level
- (2012) Georg Nübling et al. Molecular Neurodegeneration
- Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
- (2012) Peng Lei et al. NATURE MEDICINE
- Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease
- (2012) Chuang Guo et al. NEUROBIOLOGY OF AGING
- Interactions between Amyloid-β and Hemoglobin: Implications for Amyloid Plaque Formation in Alzheimer's Disease
- (2012) Jia-Ying Chuang et al. PLoS One
- Elevated Serum Ferritin Is Associated with Reduced Survival in Amyotrophic Lateral Sclerosis
- (2012) Yann Nadjar et al. PLoS One
- A neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors
- (2012) H. You et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prion protein facilitates uptake of zinc into neuronal cells
- (2012) Nicole T. Watt et al. Nature Communications
- Genetic Inhibition of Solute-Linked Carrier 39 Family Transporter 1 Ameliorates Aβ Pathology in a Drosophila Model of Alzheimer's Disease
- (2012) Minglin Lang et al. PLoS Genetics
- The Heterogeneous Nature of Cu2+Interactions with Alzheimer’s Amyloid-β Peptide
- (2011) Simon C. Drew et al. ACCOUNTS OF CHEMICAL RESEARCH
- Single particle analysis of tau oligomer formation induced by metal ions and organic solvents
- (2011) Benedikt Bader et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Toxicity of Alzheimer's disease-associated Aβ peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability
- (2011) Haiqing Hua et al. BIOLOGICAL CHEMISTRY
- Elevated labile Cu is associated with oxidative pathology in Alzheimer disease
- (2011) Simon A. James et al. FREE RADICAL BIOLOGY AND MEDICINE
- Development of Bifunctional Stilbene Derivatives for Targeting and Modulating Metal-Amyloid-β Species
- (2011) Joseph J. Braymer et al. INORGANIC CHEMISTRY
- Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Copper Chaperone of SOD1-dependent Copper/Zinc Superoxide Dismutase Activity
- (2011) Mark A. Greenough et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Different 8-Hydroxyquinolines Protect Models of TDP-43 Protein, α-Synuclein, and Polyglutamine Proteotoxicity through Distinct Mechanisms
- (2011) Daniel F. Tardiff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease
- (2011) Kazuma Murakami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cysteine Oxidation within N-terminal Mutant Huntingtin Promotes Oligomerization and Delays Clearance of Soluble Protein
- (2011) Jonathan H. Fox et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cu(II) Mediates Kinetically Distinct, Non-amyloidogenic Aggregation of Amyloid-β Peptides
- (2011) Jeppe T. Pedersen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinct Effects of Zn2+, Cu2+, Fe3+, and Al3+on Amyloid-β Stability, Oligomerization, and Aggregation
- (2011) Wei-Ting Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ALS-Causing SOD1 Mutations Promote Production of Copper-Deficient Misfolded Species
- (2011) Philbert Ip et al. JOURNAL OF MOLECULAR BIOLOGY
- The alpha-synuclein 5′untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen
- (2011) Jack T. Rogers et al. JOURNAL OF NEURAL TRANSMISSION
- Biphasic effects of copper on neurotransmission in rat hippocampal neurons
- (2011) Christian Peters et al. JOURNAL OF NEUROCHEMISTRY
- The Alzheimer’s therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity
- (2011) Peter J. Crouch et al. JOURNAL OF NEUROCHEMISTRY
- The Neurophysiology and Pathology of Brain Zinc
- (2011) S. L. Sensi et al. JOURNAL OF NEUROSCIENCE
- Molecular and genetic features of zinc transporters in physiology and pathogenesis
- (2011) Toshiyuki Fukada et al. Metallomics
- Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold
- (2011) Andreas M Grabrucker et al. Molecular Neurodegeneration
- Substantia nigra hyperechogenicity with LRRK2 G2019S mutations
- (2011) Norbert Brüggemann et al. MOVEMENT DISORDERS
- Effects of hemochromatosis and transferrin gene mutations on iron dyshomeostasis, liver dysfunction and on the risk of Alzheimer's disease
- (2011) Federica Giambattistelli et al. NEUROBIOLOGY OF AGING
- Vesicular Zinc Promotes Presynaptic and Inhibits Postsynaptic Long-Term Potentiation of Mossy Fiber-CA3 Synapse
- (2011) Enhui Pan et al. NEURON
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Gender and Iron Genes May Modify Associations Between Brain Iron and Memory in Healthy Aging
- (2011) George Bartzokis et al. NEUROPSYCHOPHARMACOLOGY
- Alpha-Synuclein Is a Cellular Ferrireductase
- (2011) Paul Davies et al. PLoS One
- Metal Ionophore Treatment Restores Dendritic Spine Density and Synaptic Protein Levels in a Mouse Model of Alzheimer's Disease
- (2011) Paul A. Adlard et al. PLoS One
- Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy
- (2011) S. C. Dodani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory
- (2010) Daniela Puzzo et al. ANNALS OF NEUROLOGY
- Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease
- (2010) James A. Duce et al. CELL
- Monomerized Cu,Zn-superoxide dismutase induces oxidative stress through aberrant Cu binding
- (2010) Hitoshi Kishigami et al. FREE RADICAL BIOLOGY AND MEDICINE
- Tau protein: Relevance to Parkinson's disease
- (2010) Peng Lei et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Copper Promotes the Trafficking of the Amyloid Precursor Protein
- (2010) Karla M. Acevedo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1
- (2010) Hyun-Hee Cho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substoichiometric Levels of Cu2+Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer Disease
- (2010) Claire J. Sarell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Copper binding regulates intracellular alpha-synuclein localisation, aggregation and toxicity
- (2010) Xiaoyan Wang et al. JOURNAL OF NEUROCHEMISTRY
- Blood-Borne Amyloid- Dimer Correlates with Clinical Markers of Alzheimer's Disease
- (2010) V. L. Villemagne et al. JOURNAL OF NEUROSCIENCE
- A Calorie-Restricted Diet Decreases Brain Iron Accumulation and Preserves Motor Performance in Old Rhesus Monkeys
- (2010) E. K. Kastman et al. JOURNAL OF NEUROSCIENCE
- Cognitive Loss in Zinc Transporter-3 Knock-Out Mice: A Phenocopy for the Synaptic and Memory Deficits of Alzheimer's Disease?
- (2010) P. A. Adlard et al. JOURNAL OF NEUROSCIENCE
- Active Site Environment of Heme-Bound Amyloid β Peptide Associated with Alzheimer’s Disease
- (2010) Debajyoti Pramanik et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Transcranial ultrasound as a risk marker for Parkinson's disease
- (2010) Daniela Berg MOVEMENT DISORDERS
- The challenges of determining metal–protein affinities
- (2010) Zhiguang Xiao et al. NATURAL PRODUCT REPORTS
- Affinity gradients drive copper to cellular destinations
- (2010) Lucia Banci et al. NATURE
- Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
- (2010) Daryl A Bosco et al. NATURE NEUROSCIENCE
- Increased brain iron coincides with early plaque formation in a mouse model of Alzheimer's disease
- (2010) Andreana C. Leskovjan et al. NEUROIMAGE
- Zinc ions promote Alzheimer A aggregation via population shift of polymorphic states
- (2010) Y. Miller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Design of small molecules that target metal-A species and regulate metal-induced A aggregation and neurotoxicity
- (2010) J.-S. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Electrochemical and homogeneous electron transfers to the Alzheimer amyloid- copper complex follow a preorganization mechanism
- (2010) V. Balland et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics
- (2010) James A. Duce et al. PROGRESS IN NEUROBIOLOGY
- Deprotonation of the Asp1Ala2 Peptide Bond Induces Modification of the Dynamic Copper(II) Environment in the Amyloid-β Peptide near Physiological pH
- (2009) Christelle Hureau et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Pulse EPR Spectroscopy Reveals the Coordination Sphere of Copper(II) Ions in the 1â16 Amyloid-β Peptide: A Key Role of the First Two N-Terminus Residues
- (2009) Pierre Dorlet et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Second Cu(II)-Binding Site in a Proton-Rich Environment Interferes with the Aggregation of Amyloid-β(1−40) into Amyloid Fibrils
- (2009) Sangmi Jun et al. BIOCHEMISTRY
- Alterations of Zinc Transporter Proteins ZnT-1, ZnT-4 and ZnT-6 in Preclinical Alzheimer's Disease Brain
- (2009) Ganna Lyubartseva et al. BRAIN PATHOLOGY
- Copper and Zinc Binding to Amyloid-β: Coordination, Dynamics, Aggregation, Reactivity and Metal-Ion Transfer
- (2009) Peter Faller CHEMBIOCHEM
- Unique copper-induced oligomers mediate alpha-synuclein toxicity
- (2009) Josephine A. Wright et al. FASEB JOURNAL
- Paradoxical Condensation of Copper with Elevated β-Amyloid in Lipid Rafts under Cellular Copper Deficiency Conditions
- (2009) Ya Hui Hung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Importance of dynamical processes in the coordination chemistry and redox conversion of copper amyloid-β complexes
- (2009) Christelle Hureau et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Copper in the brain and Alzheimer’s disease
- (2009) Ya Hui Hung et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Site-Activated Multifunctional Chelator with Acetylcholinesterase and Neuroprotective−Neurorestorative Moieties for Alzheimer’s Therapy
- (2009) Hailin Zheng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Picomolar Amyloid- Positively Modulates Synaptic Plasticity and Memory in Hippocampus
- (2009) D. Puzzo et al. JOURNAL OF NEUROSCIENCE
- Synaptically Released Zinc Triggers Metabotropic Signaling via a Zinc-Sensing Receptor in the Hippocampus
- (2009) L. Besser et al. JOURNAL OF NEUROSCIENCE
- A Role for Synaptic Zinc in Activity-Dependent A Oligomer Formation and Accumulation at Excitatory Synapses
- (2009) A. Deshpande et al. JOURNAL OF NEUROSCIENCE
- Pleomorphic Copper Coordination by Alzheimer’s Disease Amyloid-β Peptide
- (2009) Simon C. Drew et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Alanine-2 Carbonyl is an Oxygen Ligand in Cu2+Coordination of Alzheimer’s Disease Amyloid-β Peptide − Relevance to N-Terminally Truncated Forms
- (2009) Simon C. Drew et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Design, Selection, and Characterization of Thioflavin-Based Intercalation Compounds with Metal Chelating Properties for Application in Alzheimer’s Disease
- (2009) Cristina Rodríguez-Rodríguez et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Small Molecule Modulators of Copper-Induced Aβ Aggregation
- (2009) Sarmad S. Hindo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Errata
- (2009) LANCET NEUROLOGY
- Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses
- (2009) Efrat Abramov et al. NATURE NEUROSCIENCE
- Intracellular zinc inhibits KCC2 transporter activity
- (2009) Michal Hershfinkel et al. NATURE NEUROSCIENCE
- Zinc in the physiology and pathology of the CNS
- (2009) Stefano L. Sensi et al. NATURE REVIEWS NEUROSCIENCE
- Amyloid plaques in PSAPP mice bind less metal than plaques in human Alzheimer's disease
- (2009) Andreana C. Leskovjan et al. NEUROIMAGE
- Zinc-Mediated Transactivation of TrkB Potentiates the Hippocampal Mossy Fiber-CA3 Pyramid Synapse
- (2009) Yang Z. Huang et al. NEURON
- Increasing Cu bioavailability inhibits A oligomers and tau phosphorylation
- (2009) P. J. Crouch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intracellular copper deficiency increases amyloid-β secretion by diverse mechanisms
- (2008) Michael A. Cater et al. BIOCHEMICAL JOURNAL
- Ammonium tetrathiomolybdate delays onset, prolongs survival, and slows progression of disease in a mouse model for amyotrophic lateral sclerosis
- (2008) Eiichi Tokuda et al. EXPERIMENTAL NEUROLOGY
- Sequestration of Copper from β-Amyloid Promotes Selective Lysis by Cyclen-Hybrid Cleavage Agents
- (2008) Wei-hui Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intake of copper has no effect on cognition in patients with mild Alzheimer’s disease: a pilot phase 2 clinical trial
- (2008) Holger Kessler et al. JOURNAL OF NEURAL TRANSMISSION
- Transcranial sonography findings in a large family with homozygous and heterozygous PINK1 mutations
- (2008) J M Hagenah et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Zinc-Amyloid β Interactions on a Millisecond Time-Scale Stabilize Non-fibrillar Alzheimer-Related Species
- (2008) Dror Noy et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial
- (2008) Lars Lannfelt et al. LANCET NEUROLOGY
- Metal swap between Zn7-metallothionein-3 and amyloid-β–Cu protects against amyloid-β toxicity
- (2008) Gabriele Meloni et al. Nature Chemical Biology
- Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ
- (2008) Paul A. Adlard et al. NEURON
- New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals
- (2008) L. Zecca et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- Alpha-synuclein and its role in metal binding: Relevance to Parkinson's disease
- (2007) Josephine A. Wright et al. JOURNAL OF NEUROSCIENCE RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started