The Multivalent Effect in Glycosidase Inhibition: A New, Rapidly Emerging Topic in Glycoscience
出版年份 2014 全文链接
标题
The Multivalent Effect in Glycosidase Inhibition: A New, Rapidly Emerging Topic in Glycoscience
作者
关键词
-
出版物
CHEMBIOCHEM
Volume 15, Issue 9, Pages 1239-1251
出版商
Wiley
发表日期
2014-05-07
DOI
10.1002/cbic.201402026
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Iminosugar-based glycopolypeptides: glycosidase inhibition with bioinspired glycoprotein analogue micellar self-assemblies
- (2014) Colin Bonduelle et al. CHEMICAL COMMUNICATIONS
- A Convergent Strategy for the Synthesis of Second-Generation Iminosugar Clusters Using “Clickable” Trivalent Dendrons
- (2014) Antoine Joosten et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- A Systematic Investigation of Iminosugar Click Clusters as Pharmacological Chaperones for the Treatment of Gaucher Disease
- (2013) Antoine Joosten et al. CHEMBIOCHEM
- The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Valency, Peripheral Ligand Structure, and Topology with Cyclodextrin-Based Iminosugar Click Clusters
- (2013) Camille Decroocq et al. CHEMBIOCHEM
- Rescue of Functional CFTR Channels in Cystic Fibrosis: A Dramatic Multivalent Effect Using Iminosugar Cluster-Based Correctors
- (2013) Philippe Compain et al. CHEMBIOCHEM
- Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate–protein interactions
- (2013) Álvaro Martínez et al. CHEMICAL SOCIETY REVIEWS
- Bridging lectin binding sites by multivalent carbohydrates
- (2013) Valentin Wittmann et al. CHEMICAL SOCIETY REVIEWS
- Multivalent glycoconjugate syntheses and applications using aromatic scaffolds
- (2013) Yoann M. Chabre et al. CHEMICAL SOCIETY REVIEWS
- Fullerene-sp2-Iminosugar Balls as Multimodal Ligands for Lectins and Glycosidases: A Mechanistic Hypothesis for the Inhibitory Multivalent Effect
- (2013) Rocío Rísquez-Cuadro et al. CHEMISTRY-A EUROPEAN JOURNAL
- Correctors of the basic trafficking defect of the mutant F508del-CFTR that causes cystic fibrosis
- (2013) Véronique Birault et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Thiyl Glycosylation of Propargylated Octasilsesquioxane: Synthesis and Lectin-Binding Properties of Densely Glycosylated Clusters on a Cubic Platform
- (2013) Alberto Marra et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Exploring a Multivalent Approach to α-L-Fucosidase Inhibition
- (2013) Elena Moreno-Clavijo et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Pharmacological Chaperones as Therapeutics for Lysosomal Storage Diseases
- (2013) Robert E. Boyd et al. JOURNAL OF MEDICINAL CHEMISTRY
- Topological Effects and Binding Modes Operating with Multivalent Iminosugar-Based Glycoclusters and Mannosidases
- (2013) Yoan Brissonnet et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines
- (2013) Heidi M Sampson et al. Orphanet Journal of Rare Diseases
- Low-generation dendrimers with a calixarene core and based on a chiralC2-symmetric pyrrolidine as iminosugar mimics
- (2012) Marco Marradi et al. Beilstein Journal of Organic Chemistry
- Cyclodextrin-Based Iminosugar Click Clusters: The First Examples of Multivalent Pharmacological Chaperones for the Treatment of Lysosomal Storage Disorders
- (2012) Camille Decroocq et al. CHEMBIOCHEM
- sp2-Iminosugar O-, S-, and N-Glycosides as Conformational Mimics of α-Linked Disaccharides; Implications for Glycosidase Inhibition
- (2012) Elena M. Sánchez-Fernández et al. CHEMISTRY-A EUROPEAN JOURNAL
- Building Multivalent Iminosugar-Based Ligands on Calixarene Cores via Nitrone Cycloadditions
- (2012) Francesca Cardona et al. JOURNAL OF ORGANIC CHEMISTRY
- Carbohydrate Mimics and Lectins: A Source of New Drugs and Therapeutic Opportunities
- (2012) Jose J. Reina et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol–ene coupling. The observation of a striking glycoside cluster effect
- (2012) Mauro Lo Conte et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Polymer-attached zanamivir inhibits synergistically both early and late stages of influenza virus infection
- (2012) C. M. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synthesis of 1,4-triazole linked zanamivir dimers as highly potent inhibitors of influenza A and B
- (2012) Benjamin H. Fraser et al. MedChemComm
- Carbohydrate-Protein Interactions: A 3D View by NMR
- (2011) Virginia Roldós et al. CHEMBIOCHEM
- The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Architectural Parameters with Cyclodextrin-based Iminosugar Click Clusters
- (2011) Camille Decroocq et al. CHEMISTRY-A EUROPEAN JOURNAL
- The Bacterial Lectin FimH, a Target for Drug Discovery - Carbohydrate Inhibitors of Type 1 Fimbriae-Mediated Bacterial Adhesion
- (2011) Mirja Hartmann et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Pharmacological chaperone therapy for Gaucher disease: a patent review
- (2011) Juan M Benito et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Jack bean α-mannosidase (Jbα-man): Tolerance to alkali, chelating and reducing agents and energetics of catalysis and inhibition
- (2011) Avinash Kumar et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Pharmacological therapy for cystic fibrosis: From bench to bedside
- (2011) Frédéric Becq et al. Journal of Cystic Fibrosis
- Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect
- (2010) Philippe Compain et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral α-glucosidase inhibitory activity as antitumour agents
- (2010) Elena M. Sánchez-Fernández et al. CHEMICAL COMMUNICATIONS
- Attaching Zanamivir to a Polymer Markedly Enhances Its Activity Against Drug-resistant Strains of Influenza a Virus
- (2010) Alisha K. Weight et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands
- (2010) David Deniaud et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- A Cystic Fibrosis Respiratory Epithelial Cell Chronically Treated by Miglustat Acquires a Non–Cystic Fibrosis–Like Phenotype
- (2009) Caroline Norez et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Multivalent ligand presentation as a central concept to study intricate carbohydrate–protein interactions
- (2009) Narayanaswamy Jayaraman CHEMICAL SOCIETY REVIEWS
- A Click-Click Approach for the Preparation of Functionalized [5:1]-Hexaadducts of C60
- (2009) Julien Iehl et al. CHEMISTRY-A EUROPEAN JOURNAL
- Inhibitors Against Glycosidases as Medicines
- (2009) Tetsuya Kajimoto et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Treating lysosomal storage diseases with pharmacological chaperones: from concept to clinics
- (2009) Giancarlo Parenti EMBO Molecular Medicine
- Synergistic Effect of Zanamivir−Porphyrin Conjugates on Inhibition of Neuraminidase and Inactivation of Influenza Virus
- (2009) Wen-Hsien Wen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Maximising multivalency effects in protein–carbohydrate interactions
- (2009) Roland J. Pieters ORGANIC & BIOMOLECULAR CHEMISTRY
- Glycosidase inhibition: assessing mimicry of the transition state
- (2009) Tracey M. Gloster et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Generalized Anomeric Effect ingem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide Mimics
- (2009) Elena M. Sánchez-Fernández et al. ORGANIC LETTERS
- Synthesis and evaluation of dimeric lipophilic iminosugars as inhibitors of glucosylceramide metabolism
- (2009) Tom Wennekes et al. TETRAHEDRON-ASYMMETRY
- Glycomimetics and Glycodendrimers as High Affinity Microbial Anti-adhesins
- (2008) Anne Imberty et al. CHEMISTRY-A EUROPEAN JOURNAL
- Mechanistic insights into glycosidase chemistry
- (2008) David J Vocadlo et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Covalent inhibitors of glycosidases and their applications in biochemistry and biology
- (2008) B. P Rempel et al. GLYCOBIOLOGY
- The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics
- (2008) B. L. Cantarel et al. NUCLEIC ACIDS RESEARCH
- Multivalent iminosugars to modulate affinity and selectivity for glycosidases
- (2008) Jennifer Diot et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Golgi -mannosidase II cleaves two sugars sequentially in the same catalytic site
- (2008) N. Shah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A counterintuitive approach to treat enzyme deficiencies: use of enzyme inhibitors for restoring mutant enzyme activity
- (2007) Jian-Qiang Fan BIOLOGICAL CHEMISTRY
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