标题
MITF in melanoma: mechanisms behind its expression and activity
作者
关键词
BRAF<sup>V600E</sup>, Melanoma cancer plasticity, Gene regulation, MicroRNA, MITF, Oncogene, Transcription factor
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 72, Issue 7, Pages 1249-1260
出版商
Springer Nature
发表日期
2014-12-02
DOI
10.1007/s00018-014-1791-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pathways and therapeutic targets in melanoma
- (2015) Emma Shtivelman et al. Oncotarget
- MiRNA in melanoma-derived exosomes
- (2014) Anna Gajos-Michniewicz et al. CANCER LETTERS
- Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression
- (2014) G Denecker et al. CELL DEATH AND DIFFERENTIATION
- Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasis
- (2014) José A. Martina et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Targeted Therapy Resistance Mechanisms and Therapeutic Implications in Melanoma
- (2014) Guo Chen et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Molecular and genetic diversity in the metastatic process of melanoma
- (2014) Katja Harbst et al. JOURNAL OF PATHOLOGY
- Natural Compounds' Activity against Cancer Stem-Like or Fast-Cycling Melanoma Cells
- (2014) Malgorzata Sztiller-Sikorska et al. PLoS One
- Gene Expression Profiling Identifies Microphthalmia-Associated Transcription Factor (MITF) and Dickkopf-1 (DKK1) as Regulators of Microenvironment-Driven Alterations in Melanoma Phenotype
- (2014) Mariusz L. Hartman et al. PLoS One
- MicroRNA-218 inhibits melanogenesis by directly suppressing microphthalmia-associated transcription factor expression
- (2014) Jia Guo et al. RNA Biology
- A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors
- (2014) D. J. Konieczkowski et al. Cancer Discovery
- MiR-101 inhibits melanoma cell invasion and proliferation by targeting MITF and EZH2
- (2013) Chonglin Luo et al. CANCER LETTERS
- Anti-apoptotic proteins on guard of melanoma cell survival
- (2013) Mariusz L. Hartman et al. CANCER LETTERS
- Molecular and cellular pathogenesis of melanoma initiation and progression
- (2013) Tarik Regad CELLULAR AND MOLECULAR LIFE SCIENCES
- Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition
- (2013) Feng Wang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
- (2013) D. T. Frederick et al. CLINICAL CANCER RESEARCH
- MITF mutations associated with pigment deficiency syndromes and melanoma have different effects on protein function
- (2013) Christine Grill et al. HUMAN MOLECULAR GENETICS
- Neural stem cells inhibit melanin production by activation of Wnt inhibitors
- (2013) Insik Hwang et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Stat3-Targeted Therapies Overcome the Acquired Resistance to Vemurafenib in Melanomas
- (2013) Fang Liu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Phenotypic Characterization of Nevus and Tumor Patterns in MITF E318K Mutation Carrier Melanoma Patients
- (2013) Richard A. Sturm et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A Conditional Zebrafish MITF Mutation Reveals MITF Levels Are Critical for Melanoma Promotion vs. Regression In Vivo
- (2013) James A. Lister et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Transcription Factor/microRNA Axis Blocks Melanoma Invasion Program by miR-211 Targeting NUAK1
- (2013) Rachel E. Bell et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A melanocyte lineage program confers resistance to MAP kinase pathway inhibition
- (2013) Cory M. Johannessen et al. NATURE
- HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome
- (2013) J Wardwell-Ozgo et al. ONCOGENE
- Human skin neural crest progenitor cells are susceptible to BRAF V600E -induced transformation
- (2013) S M Kumar et al. ONCOGENE
- Targeting melanoma by small molecules: challenges ahead
- (2013) Rizwan Haq et al. Pigment Cell & Melanoma Research
- IFN-γinhibits basal andα-MSH-induced melanogenesis
- (2013) Jinyoung Son et al. Pigment Cell & Melanoma Research
- MITF-Independent Pro-Survival Role of BRG1-Containing SWI/SNF Complex in Melanoma Cells
- (2013) Lubica Ondrušová et al. PLoS One
- PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1
- (2013) Courtney Nicholas et al. PLoS One
- Genomic and functional characterizations of phosphodiesterase subtype 4D in human cancers
- (2013) D.-C. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma
- (2013) E. M. Van Allen et al. Cancer Discovery
- The tumor suppressor HINT1 regulates MITF and β-catenin transcriptional activity in melanoma cells
- (2012) Giannicola Genovese et al. CELL CYCLE
- Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
- (2012) Alexander Gheldof et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness
- (2012) Ester Sánchez-Tilló et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF
- (2012) V. Pogenberg et al. GENES & DEVELOPMENT
- Expression of Microphthalmia-associated Transcription Factor (MITF), Which Is Critical for Melanoma Progression, Is Inhibited by Both Transcription Factor GLI2 and Transforming Growth Factor-β
- (2012) Marie-Jeanne Pierrat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanism of Mitf inhibition and morphological differentiation effects of hirsein A on B16 melanoma cells revealed by DNA microarray
- (2012) Myra O. Villareal et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes
- (2012) Chonglin Luo et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Effect of SMURF2 Targeting on Susceptibility to MEK Inhibitors in Melanoma
- (2012) Michael P. Smith et al. JNCI-Journal of the National Cancer Institute
- Plasticity of melanoma cells induced by neural cell crest conditions and three-dimensional growth
- (2012) Stephanie Ghislin et al. MELANOMA RESEARCH
- Sphere formation and self-renewal capacity of melanoma cells is affected by the microenvironment
- (2012) Malgorzata Sztiller-Sikorska et al. MELANOMA RESEARCH
- The role of 8q24 copy number gains and c-MYC expression in amelanotic cutaneous melanoma
- (2012) Pedram Pouryazdanparast et al. MODERN PATHOLOGY
- A Phosphatidylinositol 3-Kinase-Pax3 Axis Regulates Brn-2 Expression in Melanoma
- (2012) E. Bonvin et al. MOLECULAR AND CELLULAR BIOLOGY
- Breast cancer suppressor candidate-1 (BCSC-1) is a melanoma tumor suppressor that down regulates MITF
- (2012) Silvia I. Anghel et al. Pigment Cell & Melanoma Research
- Prevalence of the E318K MITF germline mutation in Italian melanoma patients: associations with histological subtypes and family cancer history
- (2012) P. Ghiorzo et al. Pigment Cell & Melanoma Research
- Systematic classification of melanoma cells by phenotype-specific gene expression mapping
- (2012) Daniel S. Widmer et al. Pigment Cell & Melanoma Research
- Role of MicroRNA-182 in Posterior Uveal Melanoma: Regulation of Tumor Development through MITF, BCL2 and Cyclin D2
- (2012) Dongsheng Yan et al. PLoS One
- The E-box Binding Factors Max/Mnt, MITF, and USF1 Act Coordinately with FoxO to Regulate Expression of Proapoptotic and Cell Cycle Control Genes by Phosphatidylinositol 3-Kinase/Akt/Glycogen Synthase Kinase 3 Signaling
- (2011) Jolyon Terragni et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biology and Clinical Relevance of the Micropthalmia Family of Transcription Factors in Human Cancer
- (2011) Rizwan Haq et al. JOURNAL OF CLINICAL ONCOLOGY
- Inhibition of Human Melanoma Cell Growth by the Dietary Flavonoid Fisetin Is Associated with Disruption of Wnt/β-Catenin Signaling and Decreased Mitf Levels
- (2011) Deeba N. Syed et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
- (2011) Satoru Yokoyama et al. NATURE
- A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
- (2011) Corine Bertolotto et al. NATURE
- A picture of Mitf in melanoma immortality
- (2011) C R Goding ONCOGENE
- Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway
- (2011) A E Thurber et al. ONCOGENE
- Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells
- (2011) Y Cheli et al. ONCOGENE
- Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny
- (2011) Y Cheli et al. ONCOGENE
- Inhibition of coding region determinant binding protein sensitizes melanoma cells to chemotherapeutic agents
- (2011) Evisabel A. Craig et al. Pigment Cell & Melanoma Research
- Generation of melanocytes from neural crest cells
- (2011) Lukas Sommer Pigment Cell & Melanoma Research
- GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells
- (2011) Delphine Javelaud et al. Pigment Cell & Melanoma Research
- Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching
- (2011) Ossia M. Eichhoff et al. Pigment Cell & Melanoma Research
- Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor
- (2011) Glen M. Boyle et al. Pigment Cell & Melanoma Research
- The three M’s: melanoma, microphthalmia-associated transcription factor and microRNA
- (2011) Rachel E. Bell et al. Pigment Cell & Melanoma Research
- Melanoma Spheroids Grown Under Neural Crest Cell Conditions Are Highly Plastic Migratory/Invasive Tumor Cells Endowed with Immunomodulator Function
- (2011) Kiran Ramgolam et al. PLoS One
- Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF
- (2011) E. Feige et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of MITF stability by the USP13 deubiquitinase
- (2011) Xiansi Zhao et al. Nature Communications
- SWI/SNF chromatin remodeling complex is critical for the expression of microphthalmia-associated transcription factor in melanoma cells
- (2010) Jiri Vachtenheim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitf-Mdel, a novel melanocyte/melanoma-specific isoform of microphthalmia-associated transcription factor-M, as a candidate biomarker for melanoma
- (2010) Yixiang Wang et al. BMC Medicine
- An Oncogenic Role for ETV1 in Melanoma
- (2010) J. Jane-Valbuena et al. CANCER RESEARCH
- Microphthalmia-Associated Transcription Factor Controls the DNA Damage Response and a Lineage-Specific Senescence Program in Melanomas
- (2010) Sandy Giuliano et al. CANCER RESEARCH
- Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth
- (2010) T Botton et al. CELL DEATH AND DIFFERENTIATION
- Interleukins 1α and 1β secreted by some melanoma cell lines strongly reduce expression of MITF-M and melanocyte differentiation antigens
- (2010) Olga Kholmanskikh et al. INTERNATIONAL JOURNAL OF CANCER
- Heterogeneous Phenotype of Human Melanoma Cells with In Vitro and In Vivo Features of Tumor-Initiating Cells
- (2010) Michela Perego et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression
- (2010) Shujie He et al. MELANOMA RESEARCH
- MiTF links Erk1/2 kinase and p21CIP1/WAF1 activation after UVC radiation in normal human melanocytes and melanoma cells
- (2010) Feng Liu et al. Molecular Cancer
- Cell cycle inhibitor p21/ WAF1/ CIP1 as a cofactor of MITF expression in melanoma cells
- (2010) Blanka Šestáková et al. Pigment Cell & Melanoma Research
- Cancer stem cells versus phenotype-switching in melanoma
- (2010) Keith S. Hoek et al. Pigment Cell & Melanoma Research
- PAX3 and SOX10 activate MET receptor expression in melanoma
- (2010) Joseph B. Mascarenhas et al. Pigment Cell & Melanoma Research
- Wnt/β-catenin signaling is stimulated by α-melanocyte-stimulating hormone in melanoma and melanocyte cells: implication in cell differentiation
- (2010) Barbara Bellei et al. Pigment Cell & Melanoma Research
- miR-148 Regulates Mitf in Melanoma Cells
- (2010) Benedikta S. Haflidadóttir et al. PLoS One
- A Role for ATF2 in Regulating MITF and Melanoma Development
- (2010) Meera Shah et al. PLoS Genetics
- Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination
- (2009) S. Pinner et al. CANCER RESEARCH
- Cellular mechanisms regulating human melanogenesis
- (2009) H. Y. Park et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- CREB in the Pathophysiology of Cancer: Implications for Targeting Transcription Factors for Cancer Therapy
- (2009) K. M. Sakamoto et al. CLINICAL CANCER RESEARCH
- Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions
- (2009) Caroline N Mills et al. Molecular Cancer
- Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma
- (2009) B Keenen et al. ONCOGENE
- ERK-regulated differential expression of the Mitf 6a/b splicing isoforms in melanoma
- (2009) Aline Primot et al. Pigment Cell & Melanoma Research
- Frequent mutations in the MITF pathway in melanoma
- (2009) Julia C. Cronin et al. Pigment Cell & Melanoma Research
- Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor
- (2009) Miguel F. Segura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A genomic screen identifies TYRO3 as a MITF regulator in melanoma
- (2009) S. Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA-137 Targets Microphthalmia-Associated Transcription Factor in Melanoma Cell Lines
- (2008) L. T. Bemis et al. CANCER RESEARCH
- Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells
- (2008) J. Goodall et al. CANCER RESEARCH
- Inhibition of PAX3 by TGF-β Modulates Melanocyte Viability
- (2008) Guang Yang et al. MOLECULAR CELL
- Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage
- (2008) Satoru Yokoyama et al. Pigment Cell & Melanoma Research
- Novel MITF targets identified using a two-step DNA microarray strategy
- (2008) Keith S. Hoek et al. Pigment Cell & Melanoma Research
- Oncogenic BRAF Regulates Melanoma Proliferation through the Lineage Specific Factor MITF
- (2008) Claudia Wellbrock et al. PLoS One
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