Intergenerational programming of metabolic disease: evidence from human populations and experimental animal models

Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function

(2012) Nicole O. Palmer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

C. elegans piRNAs Mediate the Genome-wide Surveillance of Germline Transcripts

(2012) Heng-Chi Lee et al.   CELL

piRNAs Can Trigger a Multigenerational Epigenetic Memory in the Germline of C. elegans

(2012) Alyson Ashe et al.   CELL

TrxG and PcG Proteins but Not Methylated Histones Remain Associated with DNA through Replication

(2012) Svetlana Petruk et al.   CELL

DNA methylation at differentially methylated regions of imprinted genes is resistant to developmental programming by maternal nutrition

(2012) Elena Ivanova et al.   Epigenetics

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality

(2012) Bethany A. Buckley et al.   NATURE

Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint

(2012) Sam Guoping Gu et al.   NATURE GENETICS

Chromatin replication and epigenome maintenance

(2012) Constance Alabert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability

(2012) V. R. Nelson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function, Targets, and Evolution of Caenorhabditis elegans piRNAs

(2012) M. P. Bagijn et al.   SCIENCE

An Unbiased Assessment of the Role of Imprinted Genes in an Intergenerational Model of Developmental Programming

(2012) Elizabeth J. Radford et al.   PLoS Genetics

Seminal Plasma Proteins: What Role Do They Play?

(2011) Heriberto Rodríguez-Martínez et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Inheritance of Stress-Induced, ATF-2-Dependent Epigenetic Change

(2011) Ki-Hyeon Seong et al.   CELL

Transgenerational Inheritance of an Acquired Small RNA-Based Antiviral Response in C. elegans

(2011) Oded Rechavi et al.   CELL

You Are What Your Dad Ate

(2011) Anne C. Ferguson-Smith et al.   Cell Metabolism

Association of Maternal Diabetes Mellitus in Pregnancy With Offspring Adiposity Into Early Adulthood

(2011) Debbie A. Lawlor et al.   CIRCULATION

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

Maternal Environment and the Transgenerational Cycle of Obesity and Diabetes

(2011) D. Dabelea et al.   DIABETES

Maternal High-Fat Diet Effects on Third-Generation Female Body Size via the Paternal Lineage

(2011) Gregory A. Dunn et al.   ENDOCRINOLOGY

Variable histone modifications at the Avymetastable epiallele

(2011) Dana C. Dolinoy et al.   Epigenetics

The Impact of In Utero Exposure to Diabetes on Childhood Body Mass Index Growth Trajectories: The EPOCH Study

(2011) Tessa L. Crume et al.   JOURNAL OF PEDIATRICS

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE

Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

(2011) Eric L. Greer et al.   NATURE

Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus

(2011) T. Watanabe et al.   SCIENCE

Early Life Nutrition Modulates Muscle Stem Cell Number: Implications for Muscle Mass and Repair

(2011) Melissa Woo et al.   STEM CELLS AND DEVELOPMENT

A Role for Set1/MLL-Related Components in Epigenetic Regulation of the Caenorhabditis elegans Germ Line

(2011) Tengguo Li et al.   PLoS Genetics

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

Transgenerational Inheritance of Glucose Intolerance in a Mouse Model of Neonatal Overnutrition

(2010) Thais Pentinat et al.   ENDOCRINOLOGY

Ancestral paternal genotype controls body weight and food intake for multiple generations

(2010) Soha N. Yazbek et al.   HUMAN MOLECULAR GENETICS

The effect of paternal diet-induced obesity on sperm function and fertilization in a mouse model

(2010) H. W. Bakos et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Maternal BMI, Parity, and Pregnancy Weight Gain: Influences on Offspring Adiposity in Young Adulthood

(2010) R. M. Reynolds et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans

(2010) Eric L. Greer et al.   NATURE

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Respective Contributions of Maternal Insulin Resistance and Diet to Metabolic and Hypothalamic Phenotypes of Progeny

(2010) Jill S. Carmody et al.   Obesity

Epigenetic Transgenerational Actions of Vinclozolin on Promoter Regions of the Sperm Epigenome

(2010) Carlos Guerrero-Bosagna et al.   PLoS One

Transgenerational genetic effects of the paternal Y chromosome on daughters’ phenotypes

(2010) Vicki R Nelson et al.   Epigenomics

Transgenerational genetic effects

(2010) Vicki R Nelson et al.   Epigenomics

Male-line transgenerational responses in humans

(2010) Marcus E. Pembrey   Human Fertility

Season of Conception in Rural Gambia Affects DNA Methylation at Putative Human Metastable Epialleles

(2010) Robert A. Waterland et al.   PLoS Genetics

Potential role of multiple members of the kallikrein-related peptidase family of serine proteases in activating latent TGFβ1 in semen

(2009) Nashmil Emami et al.   BIOLOGICAL CHEMISTRY

The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth

(2009) V. Grandjean et al.   DEVELOPMENT

Accelerated Postnatal Growth Increases Lipogenic Gene Expression and Adipocyte Size in Low-Birth Weight Mice

(2009) E. Isganaitis et al.   DIABETES

Lifelong Enhanced Diabetes Susceptibility and Obesity after Temporary Intrahypothalamic Hyperinsulinism during Brain Organization

(2009) A. Plagemann et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

DNA methylation profiles in monozygotic and dizygotic twins

(2009) Zachary A Kaminsky et al.   NATURE GENETICS

The effect of the nitric oxide donor sodium nitroprusside on glucose uptake in human primary skeletal muscle cells

(2009) Darren C. Henstridge et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

A network of interactions among seminal proteins underlies the long-term postmating response in Drosophila

(2009) K. R. Ram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm

(2009) Christelle Stouder et al.   REPRODUCTION

Intergenerational influences on childhood body mass index: the effect of parental body mass index trajectories

(2008) Leah Li et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life

(2008) RC Painter et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring

(2008) Karen A. Lillycrop et al.   BRITISH JOURNAL OF NUTRITION

Diabetes Risk Begins In Utero

(2008) Melissa Woo et al.   Cell Metabolism

RNA Induction and Inheritance of Epigenetic Cardiac Hypertrophy in the Mouse

(2008) Kay D. Wagner et al.   DEVELOPMENTAL CELL

Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice

(2008) J. C. Jimenez-Chillaron et al.   DIABETES

Maternal Lipids as Strong Determinants of Fetal Environment and Growth in Pregnancies With Gestational Diabetes Mellitus

(2008) U. M. Schaefer-Graf et al.   DIABETES CARE

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Transmission Dynamics of Heritable Silencing Induced by Double-Stranded RNA in Caenorhabditis elegans

(2008) Rosa M. Alcazar et al.   GENETICS

Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function

(2008) Caroline Bertram et al.   JOURNAL OF PHYSIOLOGY-LONDON

Grandparental and Parental Obesity Influences on Childhood Overweight: Implications for Primary Care Practice

(2008) M. M. Davis et al.   Journal of the American Board of Family Medicine

Effect of In Utero and Early-Life Conditions on Adult Health and Disease

(2008) Peter D. Gluckman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Epigenetic Role for Maternally Inherited piRNAs in Transposon Silencing

(2008) J. Brennecke et al.   SCIENCE