标题
The unique features of follicular T cell subsets
作者
关键词
Germinal center, Follicular helper T cell, IL-21, Immune response, Antibody production
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 70, Issue 24, Pages 4771-4784
出版商
Springer Nature
发表日期
2013-07-13
DOI
10.1007/s00018-013-1420-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- IL-21-Induced Isotype Switching to IgG and IgA by Human Naive B Cells Is Differentially Regulated by IL-4
- (2014) D. T. Avery et al. JOURNAL OF IMMUNOLOGY
- Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection
- (2013) Noah J. Tubo et al. CELL
- Persistent Antigen and Germinal Center B Cells Sustain T Follicular Helper Cell Responses and Phenotype
- (2013) Dirk Baumjohann et al. IMMUNITY
- Roquin Paralogs 1 and 2 Redundantly Repress the Icos and Ox40 Costimulator mRNAs and Control Follicular Helper T Cell Differentiation
- (2013) Katharina U. Vogel et al. IMMUNITY
- Roquin-2 Shares Functions with Its Paralog Roquin-1 in the Repression of mRNAs Controlling T Follicular Helper Cells and Systemic Inflammation
- (2013) Alvin Pratama et al. IMMUNITY
- Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility
- (2013) Heping Xu et al. NATURE
- Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses
- (2013) Keiji Hirota et al. NATURE IMMUNOLOGY
- Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms
- (2013) Chuanxin Huang et al. NATURE IMMUNOLOGY
- Inadequate T follicular cell help impairs B cell immunity during HIV infection
- (2013) Rafael A Cubas et al. NATURE MEDICINE
- Role of the frequency of blood CD4+ CXCR5+ CCR6+ T cells in autoimmunity in patients with Sjögren’s syndrome
- (2012) Xue-yi Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Heterozygosity for Roquinsan leads to angioimmunoblastic T-cell lymphoma-like tumors in mice
- (2012) J. I. Ellyard et al. BLOOD
- Functional STAT3 deficiency compromises the generation of human T follicular helper cells
- (2012) C. S. Ma et al. BLOOD
- Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters
- (2012) F. Lemonnier et al. BLOOD
- IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma
- (2012) R. A. Cairns et al. BLOOD
- A Validated Regulatory Network for Th17 Cell Specification
- (2012) Maria Ciofani et al. CELL
- T-follicular helper cells survive as long-term memory cells
- (2012) Jan P. Weber et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Receptor Ly108 Functions as a SAP Adaptor-Dependent On-Off Switch for T Cell Help to B Cells and NKT Cell Development
- (2012) Robin Kageyama et al. IMMUNITY
- STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and Function
- (2012) Roza I. Nurieva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expansion of HIV-specific T follicular helper cells in chronic HIV infection
- (2012) Madelene Lindqvist et al. JOURNAL OF CLINICAL INVESTIGATION
- CD4 T follicular helper cell dynamics during SIV infection
- (2012) Constantinos Petrovas et al. JOURNAL OF CLINICAL INVESTIGATION
- Dual regulation of IRF4 function in T and B cells is required for the coordination of T–B cell interactions and the prevention of autoimmunity
- (2012) Partha S. Biswas et al. JOURNAL OF EXPERIMENTAL MEDICINE
- BCL6 positively regulates AID and germinal center gene expression via repression of miR-155
- (2012) Katia Basso et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
- (2012) Matthieu Perreau et al. JOURNAL OF EXPERIMENTAL MEDICINE
- STAT5 is a potent negative regulator of TFHcell differentiation
- (2012) Robert J. Johnston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
- (2012) Alex Karnowski et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CD80 Expression on B Cells Regulates Murine T Follicular Helper Development, Germinal Center B Cell Survival, and Plasma Cell Generation
- (2012) K. L. Good-Jacobson et al. JOURNAL OF IMMUNOLOGY
- IL-21 Receptor Is Required for the Systemic Accumulation of Activated B and T Lymphocytes in MRL/MpJ-Faslpr/lpr/J Mice
- (2012) A. L. Rankin et al. JOURNAL OF IMMUNOLOGY
- Interleukin 21 Correlates with T Cell and B Cell Subset Alterations in Systemic Lupus Erythematosus
- (2012) B. TERRIER et al. JOURNAL OF RHEUMATOLOGY
- BATF–JUN is critical for IRF4-mediated transcription in T cells
- (2012) Peng Li et al. NATURE
- The development and fate of follicular helper T cells defined by an IL-21 reporter mouse
- (2012) Katja Lüthje et al. NATURE IMMUNOLOGY
- Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
- (2012) Kenneth J Oestreich et al. NATURE IMMUNOLOGY
- Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation
- (2012) N. Bollig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes
- (2012) E. Glasmacher et al. SCIENCE
- A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis
- (2012) Rui Liu et al. ARTHRITIS RESEARCH & THERAPY
- Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion
- (2011) Rimpei Morita et al. IMMUNITY
- Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition
- (2011) Shingo Nakayamada et al. IMMUNITY
- Opposing Signals from the Bcl6 Transcription Factor and the Interleukin-2 Receptor Generate T Helper 1 Central and Effector Memory Cells
- (2011) Marion Pepper et al. IMMUNITY
- ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6
- (2011) Youn Soo Choi et al. IMMUNITY
- Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone
- (2011) Steven M. Kerfoot et al. IMMUNITY
- Functional and Epigenetic Studies Reveal Multistep Differentiation and Plasticity of In Vitro-Generated and In Vivo-Derived Follicular T Helper Cells
- (2011) Kristina T. Lu et al. IMMUNITY
- Bcl6 Protein Expression Shapes Pre-Germinal Center B Cell Dynamics and Follicular Helper T Cell Heterogeneity
- (2011) Masahiro Kitano et al. IMMUNITY
- Increased Frequency of Follicular Helper T Cells in Patients with Autoimmune Thyroid Disease
- (2011) Chenlu Zhu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells
- (2011) Sau K. Lee et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Loss of Roquin induces early death and immune deregulation but not autoimmunity
- (2011) Arianna Bertossi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells
- (2011) Laura M. Fahey et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B Cell-Specific Expression of B7-2 Is Required for Follicular Th Cell Function in Response to Vaccinia Virus
- (2011) S. Salek-Ardakani et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Distinct Waves of BCL6 Expression during T Follicular Helper Cell Development
- (2011) D. Baumjohann et al. JOURNAL OF IMMUNOLOGY
- CXCR5 Expressing Human Central Memory CD4 T Cells and Their Relevance for Humoral Immune Responses
- (2011) N. Chevalier et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Dendritic Cell-Restricted Antigen Presentation Initiates the Follicular Helper T Cell Program but Cannot Complete Ultimate Effector Differentiation
- (2011) R. Goenka et al. JOURNAL OF IMMUNOLOGY
- Germinal center B and follicular helper T cells: siblings, cousins or just good friends?
- (2011) Stephen L Nutt et al. NATURE IMMUNOLOGY
- The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells
- (2011) Wataru Ise et al. NATURE IMMUNOLOGY
- The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
- (2011) Erika Cretney et al. NATURE IMMUNOLOGY
- Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses
- (2011) Pheh-Ping Chang et al. NATURE IMMUNOLOGY
- Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner
- (2011) Irah L King et al. NATURE IMMUNOLOGY
- Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
- (2011) Yeonseok Chung et al. NATURE MEDICINE
- Foxp3+ follicular regulatory T cells control the germinal center response
- (2011) Michelle A Linterman et al. NATURE MEDICINE
- IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation
- (2011) Danelle Eto et al. PLoS One
- Optimal Germinal Center Responses Require a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84
- (2010) Jennifer L. Cannons et al. IMMUNITY
- Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling
- (2010) Elissa K. Deenick et al. IMMUNITY
- IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells
- (2010) Marcel Batten et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
- (2010) Michelle A. Linterman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism
- (2010) Dimitra Zotos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-21 Receptor Is Critical for the Development of Memory B Cell Responses
- (2010) A. L. Rankin et al. JOURNAL OF IMMUNOLOGY
- B and T Lymphocyte Attenuator Suppresses IL-21 Production from Follicular Th Cells and Subsequent Humoral Immune Responses
- (2010) D. Kashiwakuma et al. JOURNAL OF IMMUNOLOGY
- A Nonredundant Role for IL-21 Receptor Signaling in Plasma Cell Differentiation and Protective Type 2 Immunity against Gastrointestinal Helminth Infection
- (2010) I. L. King et al. JOURNAL OF IMMUNOLOGY
- Phosphoinositide 3-Kinase Activity in T Cells Regulates the Magnitude of the Germinal Center Reaction
- (2010) J. Rolf et al. JOURNAL OF IMMUNOLOGY
- HIV-Specific IL-21 Producing CD4+ T Cells Are Induced in Acute and Chronic Progressive HIV Infection and Are Associated with Relative Viral Control
- (2010) F. Y. Yue et al. JOURNAL OF IMMUNOLOGY
- Regulation of the IL-21 Gene by the NF- B Transcription Factor c-Rel
- (2010) G. Chen et al. JOURNAL OF IMMUNOLOGY
- PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells
- (2010) Kim L Good-Jacobson et al. NATURE IMMUNOLOGY
- Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
- (2010) Shane Crotty et al. NATURE IMMUNOLOGY
- Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
- (2009) Nicholas Simpson et al. ARTHRITIS AND RHEUMATISM
- An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization
- (2009) M. Jourdan et al. BLOOD
- The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment
- (2009) Di Yu et al. IMMUNITY
- Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors
- (2009) Hyokjoon Kwon et al. IMMUNITY
- Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12
- (2009) Cindy S Ma et al. IMMUNOLOGY AND CELL BIOLOGY
- Elevated Production of B Cell Chemokine CXCL13 is Correlated with Systemic Lupus Erythematosus Disease Activity
- (2009) C. K. Wong et al. JOURNAL OF CLINICAL IMMUNOLOGY
- The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells
- (2009) Oliver Dienz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Follicular helper T cells are required for systemic autoimmunity
- (2009) Michelle A. Linterman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- T follicular helper cells differentiate from Th2 cells in response to helminth antigens
- (2009) Arielle Glatman Zaretsky et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Dynamics and Consequences of IL-21 Production in HIV-Infected Individuals: A Longitudinal and Cross-Sectional Study
- (2009) Alexandre Iannello et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells
- (2009) C. Pot et al. JOURNAL OF IMMUNOLOGY
- c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-β inhibits c-Maf-induced IL-21 production in CD4+ T cells
- (2009) Yukiko Hiramatsu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
- (2009) Nicolas Fazilleau et al. NATURE IMMUNOLOGY
- Cytokine-secreting follicular T cells shape the antibody repertoire
- (2009) R Lee Reinhardt et al. NATURE IMMUNOLOGY
- A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice
- (2009) J. A. Bubier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches
- (2009) M. Tsuji et al. SCIENCE
- Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation
- (2009) R. J. Johnston et al. SCIENCE
- Bcl6 Mediates the Development of T Follicular Helper Cells
- (2009) R. I. Nurieva et al. SCIENCE
- Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting
- (2008) N. S. Longo et al. BLOOD
- IRF-4-Binding Protein Inhibits Interleukin-17 and Interleukin-21 Production by Controlling the Activity of IRF-4 Transcription Factor
- (2008) Qinzhong Chen et al. IMMUNITY
- A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells
- (2008) Alexis Vogelzang et al. IMMUNITY
- Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages
- (2008) Roza I. Nurieva et al. IMMUNITY
- ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity
- (2008) Jared M. Odegard et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Development and characterization of IL-21–producing CD4+T cells
- (2008) Akira Suto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
- (2008) Susan Moir et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SAP-controlled T–B cell interactions underlie germinal centre formation
- (2008) Hai Qi et al. NATURE
- The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
- (2008) Aurelie T Bauquet et al. NATURE IMMUNOLOGY
- IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
- (2008) M. Huber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Follicular dendritic cell networks of primary follicles and germinal centers: Phenotype and function
- (2008) Christopher D.C. Allen et al. SEMINARS IN IMMUNOLOGY
- Regulatory T Cells: Mechanisms of Differentiation and Function
- (2007) Steven Z. Josefowicz et al. Annual Review of Immunology
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search