From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancer

Identification and characterization of cancer initiating cells from BRCA1 related mammary tumors using markers for normal mammary stem cells

(2012) Athanassios Vassilopoulos et al.   International Journal of Biological Sciences

Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome

(2010) Andrey I. Khramtsov et al.   AMERICAN JOURNAL OF PATHOLOGY

Cyclin D1 Kinase Activity Is Required for the Self-Renewal of Mammary Stem and Progenitor Cells that Are Targets of MMTV-ErbB2 Tumorigenesis

(2010) Rinath Jeselsohn et al.   CANCER CELL

Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content

(2010) Salvatore Pece et al.   CELL

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

(2010) Ö Yalcin-Ozuysal et al.   CELL DEATH AND DIFFERENTIATION

Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture

(2010) Yi Arial Zeng et al.   Cell Stem Cell

s-SHIP promoter expression marks activated stem cells in developing mouse mammary tissue

(2010) L. Bai et al.   GENES & DEVELOPMENT

Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

(2010) Douglas S. Micalizzi et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Control of mammary stem cell function by steroid hormone signalling

(2010) Marie-Liesse Asselin-Labat et al.   NATURE

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

(2010) J. H. Taube et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland

(2010) M. Beleut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Good cells gone bad: the cellular origins of cancer

(2010) Jean C.Y. Wang   TRENDS IN MOLECULAR MEDICINE

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

(2009) B. T. Hennessy et al.   CANCER RESEARCH

The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

(2009) Angelo Cicalese et al.   CELL

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: Failure of Stat5 activation and functional differentiation in the absence of Elf5

(2009) Yeon Sook Choi et al.   DEVELOPMENTAL BIOLOGY

Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A

(2009) D. Yamaji et al.   GENES & DEVELOPMENT

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage

(2009) Nisha M. Badders et al.   PLoS One

A Novel Mouse Model for Non-Invasive Single Marker Tracking of Mammary Stem Cells In Vivo Reveals Stem Cell Dynamics throughout Pregnancy

(2009) Benjamin J. Tiede et al.   PLoS One

Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype

(2008) D. Sarrio et al.   CANCER RESEARCH

Identification of Tumor-Initiating Cells in a p53-Null Mouse Model of Breast Cancer

(2008) M. Zhang et al.   CANCER RESEARCH

The Mammary Progenitor Marker CD61/ 3 Integrin Identifies Cancer Stem Cells in Mouse Models of Mammary Tumorigenesis

(2008) F. Vaillant et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment

(2008) Toula Bouras et al.   Cell Stem Cell

Mammary development in the embryo and adult: a journey of morphogenesis and commitment

(2008) C. J. Watson et al.   DEVELOPMENT

Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B

(2008) L. Hennighausen et al.   GENES & DEVELOPMENT

The Ets transcription factor Elf5 specifies mammary alveolar cell fate

(2008) S. R. Oakes et al.   GENES & DEVELOPMENT

β1 Integrin deletion from the basal compartment of the mammary epithelium affects stem cells

(2008) Ilaria Taddei et al.   NATURE CELL BIOLOGY

A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability

(2008) Peter Eirew et al.   NATURE MEDICINE

BRCA1 regulates human mammary stem/progenitor cell fate

(2008) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reciprocal Intraepithelial Interactions Between TP63 and Hedgehog Signaling Regulate Quiescence and Activation of Progenitor Elaboration by Mammary Stem Cells

(2008) Na Li et al.   STEM CELLS

Evidence That an Early Pregnancy Causes a Persistent Decrease in the Number of Functional Mammary Epithelial Stem Cells-Implications for Pregnancy-Induced Protection Against Breast Cancer

(2008) Stefan K. Siwko et al.   STEM CELLS

Altered mammary gland development in the p53+/m mouse, a model of accelerated aging

(2007) Catherine E. Gatza et al.   DEVELOPMENTAL BIOLOGY

Isolation and Molecular Characterization of Cancer Stem Cells in MMTV-Wnt-1Murine Breast Tumors

(2007) Robert W. Cho et al.   STEM CELLS