MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity

Reduced transcriptional activity in the p53 pathway of senescent cells revealed by the MDM2 antagonist nutlin-3

(2016) Baoying Huang et al.   Aging-US

The nucleolar SUMO-specific protease SMT3IP1/SENP3 attenuates Mdm2-mediated p53 ubiquitination and degradation

(2011) Tamotsu Nishida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Downregulation of ΔNp63α in keratinocytes by p14ARF-mediated SUMO-conjugation and degradation

(2011) Maria Vivo et al.   CELL CYCLE

One Function—Multiple Mechanisms: The Manifold Activities of p53 as a Transcriptional Repressor

(2011) Levin Böhlig et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

(2011) Kyung-Sun Heo et al.   JOURNAL OF CELL BIOLOGY

Mechanisms, regulation and consequences of protein SUMOylation

(2010) Kevin A. Wilkinson et al.   BIOCHEMICAL JOURNAL

SUMO chains: polymeric signals: Figure 1

(2010) Alfred C.O. Vertegaal   BIOCHEMICAL SOCIETY TRANSACTIONS

p53-Ubl fusions as models of ubiquitination, sumoylation and neddylation of p53

(2010) Stephanie A. Carter et al.   CELL CYCLE

Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3

(2010) Mei-Ling Kuo et al.   CELL CYCLE

Nucleostemin

(2010) Dorothy Lo et al.   CELL CYCLE

Mechanism of p53 stabilization by ATM after DNA damage

(2010) Qian Cheng et al.   CELL CYCLE

Functional mimicry of the acetylated C-terminal tail of p53 by a SUMO-1 acetylated domain, SAD

(2010) Amrita Cheema et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Adenovirus E1B 55-Kilodalton Protein Is a p53-SUMO1 E3 Ligase That Represses p53 and Stimulates Its Nuclear Export through Interactions with Promyelocytic Leukemia Nuclear Bodies

(2010) M. A. Pennella et al.   JOURNAL OF VIROLOGY

SUMO E3 ligase activity of TRIM proteins

(2010) Y Chu et al.   ONCOGENE

NUB1 promotes cytoplasmic localization of p53 through cooperation of the NEDD8 and ubiquitin pathways

(2010) G Liu et al.   ONCOGENE

SUMO association with repressor complexes, emerging routes for transcriptional control

(2009) Mario Garcia-Dominguez et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

Small ubiquitin-related modifier paralogs are indispensable but functionally redundant during early development of zebrafish

(2009) Hao Yuan et al.   CELL RESEARCH

Regulation of p53 family members by the ubiquitin-like SUMO system

(2009) Per Stehmeier et al.   DNA REPAIR

Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding

(2009) Shwu-Yuan Wu et al.   EMBO JOURNAL

Kaposi's Sarcoma-associated Herpesvirus (KSHV) Encodes a SUMO E3 ligase That Is SIM-dependent and SUMO-2/3-specific

(2009) Pei-Ching Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUMO under stress: Figure 1

(2008) Denis Tempé et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Modification ofDrosophilap53 by SUMO Modulates Its Transactivation and Pro-apoptotic Functions

(2008) Federico Mauri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting tumor cells expressing p53 with a water-soluble inhibitor of Hdm2

(2008) J. Kitagaki et al.   MOLECULAR CANCER THERAPEUTICS

The Fast-Growing Business of SUMO Chains

(2008) Helle D. Ulrich   MOLECULAR CELL