UniPR129 is a competitive small molecule Eph-ephrin antagonist blockingin vitroangiogenesis at low micromolar concentrations
出版年份 2014 全文链接
标题
UniPR129 is a competitive small molecule Eph-ephrin antagonist blockingin vitroangiogenesis at low micromolar concentrations
作者
关键词
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出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 171, Issue 23, Pages 5195-5208
出版商
Wiley
发表日期
2014-03-06
DOI
10.1111/bph.12669
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Concise Guide to PHARMACOLOGY 2013/14: Catalytic Receptors
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- HTS by NMR of Combinatorial Libraries: A Fragment-Based Approach to Ligand Discovery
- (2013) Bainan Wu et al. CHEMISTRY & BIOLOGY
- Target Hopping as a Useful Tool for the Identification of Novel EphA2 Protein-Protein Antagonists
- (2013) Massimiliano Tognolini et al. ChemMedChem
- Amino Acid Conjugates of Lithocholic Acid As Antagonists of the EphA2 Receptor
- (2013) Matteo Incerti et al. JOURNAL OF MEDICINAL CHEMISTRY
- Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth
- (2012) M. A. Abengozar et al. BLOOD
- Regulation of apoptosis in HL-1 cardiomyocytes by phosphorylation of the receptor tyrosine kinase EphA2 and protection by lithocholic acid
- (2012) J Jehle et al. BRITISH JOURNAL OF PHARMACOLOGY
- The EphA2 Receptor Drives Self-Renewal and Tumorigenicity in Stem-like Tumor-Propagating Cells from Human Glioblastomas
- (2012) Elena Binda et al. CANCER CELL
- Structure-Activity Relationships and Mechanism of Action of Eph-ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor
- (2012) Massimiliano Tognolini et al. ChemMedChem
- Perturbation of the EphA2–EphrinA1 System in Human Prostate Cancer Cells by Colonic (Poly)phenol Catabolites
- (2012) Massimiliano Tognolini et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
- (2012) Annelies Van Hoecke et al. NATURE MEDICINE
- Inhibition of Eph receptor–ephrin ligand interaction by tea polyphenols
- (2012) Roberta Noberini et al. PHARMACOLOGICAL RESEARCH
- A Small Molecule Agonist of EphA2 Receptor Tyrosine Kinase Inhibits Tumor Cell Migration In Vitro and Prostate Cancer Metastasis In Vivo
- (2012) Aaron Petty et al. PLoS One
- A Disalicylic Acid-Furanyl Derivative Inhibits Ephrin Binding to a Subset of Eph Receptors
- (2011) Roberta Noberini et al. Chemical Biology & Drug Design
- Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase
- (2011) Oscar P.J. van Linden et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Polyphenol rich botanicals used as food supplements interfere with EphA2–ephrinA1 system
- (2011) Iftiin Hassan Mohamed et al. PHARMACOLOGICAL RESEARCH
- Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation
- (2011) Carmine Giorgio et al. PLoS One
- Targeting Eph receptors with peptides and small molecules: Progress and challenges
- (2011) Roberta Noberini et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis
- (2010) Georg Martiny-Baron et al. ANGIOGENESIS
- EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting
- (2010) Simona Parrinello et al. CELL
- Emerging strategies for EphA2 receptor targeting for cancer therapeutics
- (2010) Manish Tandon et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
- (2010) Jonathan B. Baell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Biomarkers to predict the clinical efficacy of bevacizumab in cancer
- (2010) Adrian M Jubb et al. LANCET ONCOLOGY
- Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis
- (2010) Suphansa Sawamiphak et al. NATURE
- Architecture of Eph receptor clusters
- (2010) J. P. Himanen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex
- (2009) Juha P Himanen et al. EMBO REPORTS
- Structure-Based Optimization of Potent and Selective Inhibitors of the Tyrosine Kinase Erythropoietin Producing Human Hepatocellular Carcinoma Receptor B4 (EphB4)
- (2009) Karine Lafleur et al. JOURNAL OF MEDICINAL CHEMISTRY
- Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors
- (2008) Roberta Noberini et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Induction of cell retraction by the combined actions of Abl–CrkII and Rho–ROCK1 signaling
- (2008) XiaoDong Huang et al. JOURNAL OF CELL BIOLOGY
- MM-GB/SA Rescoring of Docking Poses in Structure-Based Lead Optimization
- (2008) Cristiano R. W. Guimarães et al. Journal of Chemical Information and Modeling
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