Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders
出版年份 2014 全文链接
标题
Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders
作者
关键词
-
出版物
BRITISH JOURNAL OF PHARMACOLOGY
Volume 171, Issue 24, Pages 5757-5773
出版商
Wiley
发表日期
2014-08-13
DOI
10.1111/bph.12875
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Decreased neuronal autophagy in HIV dementia: A mechanism of indirect neurotoxicity
- (2014) Mehrdad Alirezaei et al. Autophagy
- The Concise Guide to PHARMACOLOGY 2013/14: Catalytic Receptors
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Transporters
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Concise Guide to PHARMACOLOGY 2013/14: Enzymes
- (2013) Stephen P.H. Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Lapatinib induces p27Kip1-dependent G₁ arrest through both transcriptional and post-translational mechanisms
- (2013) Lin Tang et al. CELL CYCLE
- Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro
- (2013) Grzegorz A. Czapski et al. FEBS LETTERS
- RON Receptor Tyrosine Kinase, a Negative Regulator of Inflammation, Is Decreased during Simian Immunodeficiency Virus-Associated Central Nervous System Disease
- (2013) D. C. Cary et al. JOURNAL OF IMMUNOLOGY
- Alterations in the Levels of Vesicular Trafficking Proteins Involved in HIV Replication in the Brains and CSF of Patients with HIV-associated Neurocognitive Disorders
- (2013) Jerel Fields et al. Journal of Neuroimmune Pharmacology
- Expression of Ephrin Receptors and Ligands in Postmortem Brains of HIV-Infected Subjects With and Without Cognitive Impairment
- (2013) Vadim Yuferov et al. Journal of Neuroimmune Pharmacology
- Sunitinib enhances neuronal survival in vitro via NF-κB-mediated signaling and expression of cyclooxygenase-2 and inducible nitric oxide synthase
- (2013) Alma Sanchez et al. Journal of Neuroinflammation
- The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
- (2013) Adam J. Pawson et al. NUCLEIC ACIDS RESEARCH
- Effector mechanisms of sunitinib-induced G1 cell cycle arrest, differentiation, and apoptosis in human acute myeloid leukaemia HL60 and KG-1 cells
- (2012) Chieh-Lin Jerry Teng et al. ANNALS OF HEMATOLOGY
- A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2
- (2012) Mathew P. Martin et al. CHEMBIOCHEM
- Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation
- (2012) Crystal Bethel-Brown et al. Journal of Neuroinflammation
- Soluble and Cell-Associated Insulin Receptor Dysfunction Correlates with Severity of HAND in HIV-Infected Women
- (2012) Yamil Gerena et al. PLoS One
- Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine
- (2011) Christina Patrick et al. AMERICAN JOURNAL OF PATHOLOGY
- HIV-1 Tat binds to SH3 domains: Cellular and viral outcome of Tat/Grb2 interaction
- (2011) Slava Rom et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Novel purine-based fluoroaryl-1,2,3-triazoles as neuroprotecting agents: Synthesis, neuronal cell culture investigations, and CDK5 docking studies
- (2011) Nanditha Nair et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration
- (2011) Seng Chuan Tang et al. INTERNATIONAL JOURNAL OF CANCER
- Autophagy Is Increased in Postmortem Brains of Persons With HIV-1-Associated Encephalitis
- (2011) Dejiang Zhou et al. JOURNAL OF INFECTIOUS DISEASES
- Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders
- (2011) Leslie Crews et al. Molecular Neurodegeneration
- HIV-1-Infected and Immune-Activated Macrophages Induce Astrocytic Differentiation of Human Cortical Neural Progenitor Cells via the STAT3 Pathway
- (2011) Hui Peng et al. PLoS One
- Guidelines for reporting experiments involving animals: the ARRIVE guidelines
- (2010) JC McGrath et al. BRITISH JOURNAL OF PHARMACOLOGY
- Animal research: Reporting in vivo experiments: The ARRIVE guidelines
- (2010) Carol Kilkenny et al. BRITISH JOURNAL OF PHARMACOLOGY
- New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis
- (2010) Yan Wang et al. JOURNAL OF HEPATOLOGY
- HIV-Associated Neurocognitive Disorder: Pathogenesis and Therapeutic Opportunities
- (2010) Kathryn A. Lindl et al. Journal of Neuroimmune Pharmacology
- Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease
- (2010) Myoung-Hwa Lee et al. NEUROBIOLOGY OF DISEASE
- Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy
- (2010) Leslie Crews et al. PLoS One
- Delayed Treatment with Systemic (S)-Roscovitine Provides Neuroprotection and Inhibits In Vivo CDK5 Activity Increase in Animal Stroke Models
- (2010) Bénédicte Menn et al. PLoS One
- Neurodegeneration in an Aβ-induced model of Alzheimer’s disease: the role of Cdk5
- (2009) Joao P. Lopes et al. AGING CELL
- Kinase Inhibitors as Potential Therapeutics for Acute and Chronic Neurodegenerative Conditions
- (2009) G. Cuny CURRENT PHARMACEUTICAL DESIGN
- Molecular Pathology of Neuro-AIDS (CNS-HIV)
- (2009) Leslie Crews et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders
- (2009) Dawn Eggert et al. JOURNAL OF NEUROIMMUNOLOGY
- Lithium therapy for human immunodeficiency virus type 1–associated neurocognitive impairment
- (2009) Giovanni Schifitto et al. JOURNAL OF NEUROVIROLOGY
- Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways
- (2009) Suraiya Rasheed et al. Journal of Translational Medicine
- HIV-1 Tat Activates Neuronal Ryanodine Receptors with Rapid Induction of the Unfolded Protein Response and Mitochondrial Hyperpolarization
- (2008) John P. Norman et al. PLoS One
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