Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy

Disrupting CD47-SIRPα axis alone or combined with autophagy depletion for the therapy of glioblastoma

(2018) Xuyao Zhang et al.   CARCINOGENESIS

Chemotherapy induces enrichment of CD47+/CD73+/PDL1+immune evasive triple-negative breast cancer cells

(2018) Debangshu Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploiting a new strategy to induce immunogenic cell death to improve dendritic cell-based vaccines for lymphoma immunotherapy

(2017) B. Montico et al.   OncoImmunology

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cells

(2016) Baoqing Guo et al.   BMC CANCER

Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer

(2016) Katherine L. Cook et al.   CANCER RESEARCH

Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome AcidificationCLINICAL PERSPECTIVE

(2016) Dan L. Li et al.   CIRCULATION

Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer

(2016) D. H. Hamilton et al.   CLINICAL CANCER RESEARCH

Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment

(2016) Hanna Starobinets et al.   JOURNAL OF CLINICAL INVESTIGATION

Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline

(2016) Lyndsay N. Harris et al.   JOURNAL OF CLINICAL ONCOLOGY

A function-blocking CD47 antibody suppresses stem cell and EGF signaling in triple-negative breast cancer

(2016) Sukhbir Kaur et al.   Oncotarget

Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors

(2016) Guido Kroemer et al.   Oncotarget

Monitoring of autophagy is complicated—salinomycin as an example

(2015) Jaganmohan Reddy Jangamreddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Continued value of adjuvant anthracyclines as treatment for early breast cancer

(2015) Natalie Turner et al.   LANCET ONCOLOGY

Anti-CD47 antibody suppresses tumour growth and augments the effect of chemotherapy treatment in hepatocellular carcinoma

(2015) Jessica Lo et al.   LIVER INTERNATIONAL

CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

(2015) Xiaojuan Liu et al.   NATURE MEDICINE

HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells

(2015) Huimin Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy

(2014) D. R. Soto-Pantoja et al.   CANCER RESEARCH

The Four Faces of Autophagy: Implications for Cancer Therapy

(2014) D. A. Gewirtz   CANCER RESEARCH

Autosis and autophagic cell death: the dark side of autophagy

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Autophagy as a pro-death pathway

(2014) Donna Denton et al.   IMMUNOLOGY AND CELL BIOLOGY

An impedance-based cytotoxicity assay for real-time and label-free assessment of T-cell-mediated killing of adherent cells

(2014) Janet Kerstin Peper et al.   JOURNAL OF IMMUNOLOGICAL METHODS

CD47 Expression on T Cell Is a Self-Control Negative Regulator of Type 1 Immune Response

(2014) S. Bouguermouh et al.   JOURNAL OF IMMUNOLOGY

Evaluation and Management of Patients With Heart Disease and Cancer: Cardio-Oncology

(2014) Joerg Herrmann et al.   MAYO CLINIC PROCEEDINGS

Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity

(2013) Debapriya Dutta et al.   Autophagy

Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials

(2013)   LANCET

Blockade of CD47 increases survival of mice exposed to lethal total body irradiation

(2013) David R. Soto-Pantoja et al.   Scientific Reports

CD47 deficiency confers cell and tissue radioprotection by activation of autophagy

(2012) David R. Soto-Pantoja et al.   Autophagy

Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47

(2012) David R Soto-Pantoja et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

CD47 expression regulated by the miR-133a tumor suppressor is a novel prognostic marker in esophageal squamous cell carcinoma

(2012) SHIGEMASA SUZUKI et al.   ONCOLOGY REPORTS

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

(2012) S. B. Willingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correlated Expression of CD47 and SIRPA in Bone Marrow and in Peripheral Blood Predicts Recurrence in Breast Cancer Patients

(2010) M. Nagahara et al.   CLINICAL CANCER RESEARCH

Mechanisms of Anthracycline Cardiac Injury: Can We Identify Strategies for Cardioprotection?

(2010) Douglas B. Sawyer et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Macrophages as mediators of tumor immunosurveillance

(2010) Siddhartha Jaiswal et al.   TRENDS IN IMMUNOLOGY

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells

(2009) K. S. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radioprotection in Normal Tissue and Delayed Tumor Growth by Blockade of CD47 Signaling

(2009) J. B. Maxhimer et al.   Science Translational Medicine

Differential Interactions of Thrombospondin-1, -2, and -4 with CD47 and Effects on cGMP Signaling and Ischemic Injury Responses

(2008) Jeff S. Isenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY