Article
Anatomy & Morphology
Viola Oldrati, Elisabetta Ferrari, Niccolo Butti, Zaira Cattaneo, Renato Borgatti, Cosimo Urgesi, Alessandra Finisguerra
Summary: This study found specific involvement of the cerebellum in forming expectations related to social events, and explored the potential rehabilitative effects of cerebellar transcranial Direct Current Stimulation (ctDCS) in patients with social perception deficits.
BRAIN STRUCTURE & FUNCTION
(2021)
Review
Neurosciences
Z. Cattaneo, C. Ferrari, A. Ciricugno, E. Heleven, D. J. L. G. Schutter, M. Manto, F. Van Overwalle
Summary: Research on the role of the posterior cerebellum in social and affective cognition using various brain stimulation methods has been reviewed. The functional role of the posterior cerebellum in processes such as mood regulation and social cognition may be explained by a generic prediction mechanism, and could involve different cortico-cerebellar and cerebellar limbic networks. Stimulation approaches such as paired-pulse TMS and frequency-tuned stimulation provide insights into cerebro-cerebellar circuits and potential clinical applications for improving social and affective skills associated with cerebellar abnormalities.
Article
Neurosciences
Ted Maldonado, Jessica A. Bernard
Summary: The study confirmed the contributions of the cerebellum to cognitive processing, especially in verbal working memory and sequence learning. The effects of stimulation may be load-specific, with anodal stimulation impacting performance during effortful processing, while cathodal stimulation hindering task performance.
Article
Neurosciences
Qiming Yuan, Hehui Li, Boqi Du, Qinpu Dang, Qianwen Chang, Zhaoqi Zhang, Man Zhang, Guosheng Ding, Chunming Lu, Taomei Guo
Summary: Using techniques such as functional magnetic resonance imaging (fMRI) and transcranial direct current stimulation (tDCS), researchers have found that in bilingual language production, the bilateral cerebellar lobules have different functions. The results indicate that the right cerebellum is more involved in language control, while the left cerebellum plays a computational role in cognitive control and connects with more areas of the brain.
Review
Behavioral Sciences
Jessica A. Bernard
Summary: With the growing population of older adults, understanding brain and cognitive aging, especially the role of the cerebellum, is crucial. Integrating the cerebellum into models of cognitive aging is a significant step forward and could enhance our understanding of neurodegenerative diseases like Alzheimer's.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Neurosciences
Rebecca Herzog, Till M. Berger, Martje G. Pauly, Honghu Xue, Elmar Rueckert, Alexander Muenchau, Tobias Baeumer, Anne Weissbach
Summary: Transcranial current stimulation techniques can induce cortical plasticity. The cerebellum, an important relay in the motor system, is a promising target for plasticity induction. This study compared the effects of different tCS methods on cerebellar plasticity and found that 50 Hz tACS was the most effective in changing corticospinal excitability.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Psychology, Clinical
Beatriz Catoira, Frank Van Overwalle, Peter Van Schuerbeek, Hubert Raeymaekers, Elien Heleven, Kris Baetens, Natacha Deroost, Chris Baeken
Summary: Research on the role of the cerebellum in social behavior and its connection to social mentalizing is in its early stages. Social mentalizing involves the ability to attribute mental states to others, and is thought to rely on social action sequences stored in the cerebellum. To investigate this further, we used cerebellar transcranial direct current stimulation (tDCS) on 23 healthy participants in an MRI scanner, and measured their brain activity while performing a task that required generating sequences involving false and true beliefs, social routines, and non-social events. The results showed that stimulation reduced task performance and decreased brain activation in mentalizing areas, particularly for true belief sequences. These findings support the role of the cerebellum in the mentalizing network and belief mentalizing, advancing our understanding of its involvement in social sequences.
INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY
(2023)
Article
Neurosciences
Chiara Ferrari, Andrea Ciricugno, Maria Arioli, Zaira Cattaneo
Summary: The medial sectors of the posterior cerebellum are involved in basic emotional recognition, while the lateral sectors are recruited for higher-level social inference. Moreover, the contribution of the cerebellum in these processes is limited to negative emotional stimuli.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Psychology, Multidisciplinary
Lisa Fleury, Francesco Panico, Alexandre Foncelle, Patrice Revol, Ludovic Delporte, Sophie Jacquin-Courtois, Christian Collet, Yves Rossetti
Summary: Prism adaptation is a useful method to study sensorimotor adaptation, and the cerebellum plays an important role in the transfer of after-effects. This study aimed to explore whether anodal stimulation of the cerebellum could enhance after-effects transfer from throwing to pointing in novice participants. The results showed that active stimulation did not have significant beneficial effects on error reduction or throwing after-effects, but it had an effect on the longitudinal evolution of pointing errors and on pointing kinematic parameters during transfer assessment.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Neurosciences
Daniela Mannarelli, Caterina Pauletti, Alessia Petritis, Andrea Maffucci, Antonio Curra, Carlo Trompetto, Lucio Marinelli, Francesco Fattapposta
Summary: Time management is crucial in human behavior and cognition. Different brain regions, including the basal nuclei and cerebellum, appear to be involved in motor timing and time estimation. This study investigates the role of the cerebellum in temporal processing and suggests that it plays a role in interval discrimination for certain time ranges.
NEUROSCIENCE LETTERS
(2023)
Article
Neurosciences
Jaya Shanker Tedla, Devika Rani Sangadala, Ravi Shankar Reddy, Kumar Gular, Snehil Dixit
Summary: This review examines the effect of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on cognitive functions, finding that anodal HD-tDCS stimulation is significantly effective in treating disordered consciousness and improving memory, speech, cognition, and execution.
Review
Neurosciences
Vicente Quiles, Laura Ferrero, Eduardo Ianez, Mario Ortiz, Jose M. Azorin
Summary: This article provides a comprehensive analysis of literature works on the applications of transcranial direct current stimulation (tDCS). The work aims to analyze the specific characteristics of lower-limb stimulation, identify the strengths and weaknesses of these works, and relate them to the current knowledge of tDCS. The ultimate goal is to propose areas of improvement for more effective stimulation therapies with less variability.
Article
Medicine, General & Internal
Giordano D'Urso, Elena Toscano, Veronica Sanges, Anne Sauvaget, Christine E. Sheffer, Maria Pia Riccio, Roberta Ferrucci, Felice Iasevoli, Alberto Priori, Carmela Bravaccio, Andrea de Bartolomeis
Summary: Transcranial direct current stimulation (tDCS) applied to the cerebellar lobe shows potential in reducing the severity of symptoms in patients with autism spectrum disorder (ASD). In this pilot study, 20 sessions of cathodal stimulation resulted in a 25% reduction in global severity of symptoms, with improvements in multiple subscales. The treatment was well-tolerated without serious adverse events.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Nubia Ribeiro Conceicao, Lilian Teresa Bucken Gobbi, Priscila Nobrega-Sousa, Diego Orcioli-Silva, Victor Spiandor Beretta, Ellen Lirani-Silva, Alexandre Hideki Okano, Rodrigo Vitorio
Summary: Adding anodal tDCS over the PFC to a session of aerobic exercise led to immediate positive effects on gait variability, processing speed, and executive control of walking in people with PD.
NEUROREHABILITATION AND NEURAL REPAIR
(2021)
Article
Neurosciences
Mario Manto, Georgios P. D. Argyropoulos, Tommaso Bocci, Pablo A. Celnik, Louise A. Corben, Matteo Guidetti, Giacomo Koch, Alberto Priori, John C. Rothwell, Anna Sadnicka, Danny Spampinato, Yoshikazu Ugawa, Maximilian J. Wessel, Roberta Ferrucci
Summary: The cerebellum is connected to various regions of the brain and plays a role in motor control, cognitive processes, emotional processing, and behavior. Non-invasive brain stimulation techniques are being used to indirectly affect dysfunctional brain circuits, but there are still many unanswered questions.
Article
Neurosciences
Nick M. Kitchen, R. Chris Miall
EXPERIMENTAL BRAIN RESEARCH
(2019)
Article
Engineering, Biomedical
Orna Rosenthal, Alan M. Wing, Jeremy L. Wyatt, David Punt, Briony Brownless, Chit Ko-Ko, R. Christopher Miall
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2019)
Correction
Engineering, Biomedical
Orna Rosenthal, Alan M. Wing, Jeremy L. Wyatt, David Punt, Briony Brownless, Chit Ko-Ko, R. Christopher Miall
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2019)
Review
Behavioral Sciences
Daniele Caligiore, Michael A. Arbib, R. Chris Miall, Gianluca Baldassarre
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2019)
Article
Neurosciences
Chin-Hsuan Lin, Tim M. Tierney, Niall Holmes, Elena Boto, James Leggett, Sven Bestmann, Richard Bowtell, Matthew J. Brookes, Gareth R. Barnes, R. Chris Miall
JOURNAL OF PHYSIOLOGY-LONDON
(2019)
Article
Clinical Neurology
Matthew Weightman, John-Stuart Brittain, David Punt, R. Chris Miall, Ned Jenkinson
Article
Neurosciences
Sean Coulborn, Howard Bowman, R. Chris Miall, Davinia Fernandez-Espejo
FRONTIERS IN HUMAN NEUROSCIENCE
(2020)
Article
Neurosciences
Nick M. Kitchen, R. Chris Miall
Summary: This study found that age-related proprioceptive deficits are unrelated to accuracy in rapid arm movements, and do not impact force-field adaptation. Regardless of visual feedback conditions, physically inactive individuals perform worse in proprioceptive errors.
EXPERIMENTAL BRAIN RESEARCH
(2021)
Article
Clinical Neurology
Mike Gilbert, R. Chris Miall
Summary: In the cerebellum, mossy fiber input is recoded into internal signals before being transmitted to Purkinje cells for output. The process of recoding is essential for confining the effect of certain variables and utilizing statistical coding for reliable and precise effects. This mechanism helps normalize diverse input signals and maintain the basic circuit structure of the cerebellum across different species.
Article
Multidisciplinary Sciences
Matthew Weightman, John-Stuart Brittain, R. Chris Miall, Ned Jenkinson
Summary: The study demonstrates the differential effects of cathodal transcranial direct current stimulation (TDCS) on motor adaptation of proximal and distal upper-limb movements. While cathodal TDCS over the cerebellum impairs whole-arm movements, it enhances hand movements, suggesting a modulation of excitability between the cerebellum and M1.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
R. Christopher Miall, Daria Afanasyeva, Jonathan D. Cole, Peggy Mason
Summary: The research contrasted two deafferented adults in terms of their mental representations of the body and perceptual task performance. Differences were found in accuracy of hand shape and arm length, with one participant demonstrating better conscious awareness. Reach distance estimation and attentional bias also varied among the participants.
EXPERIMENTAL BRAIN RESEARCH
(2021)
Article
Neurosciences
R. Chris Miall, Daria Afanasyeva, Jonathan D. Cole, Peggy Mason
Summary: Studies have shown that regaining some motor control after adult-onset loss of proprioceptive and touch input heavily depends on cognitive control. By contrasting the performance of IW and KS, it is suggested that KS may have some advantage in automating simple visually-guided actions. In contrast, IW is unable to achieve this level of automation. The dual task of writing and drawing performed with and without an audio-verbal echoing task showed differences in visuo-motor performance between the two individuals.
EXPERIMENTAL BRAIN RESEARCH
(2021)
Article
Clinical Neurology
Matthew Weightman, Neeraj Lalji, Chin-Hsuan Sophie Lin, Joseph M. Galea, Ned Jenkinson, R. Chris Miall
Summary: Brief bursts of anodal stimulation to the cerebellum during a visuomotor adaptation task were found to enhance motor adaptation significantly better than standard TDCS. Short duration, event related, anodal TDCS targeting the cerebellum enhances motor adaptation compared to the standard model.
Article
Psychology, Experimental
Alix G. Renault, Hannah Lefumat, R. Chris Miall, Lionel Bringoux, Christophe Bourdin, Jean-Louis Vercher, Fabrice R. Sarlegna
PSYCHOLOGICAL RESEARCH-PSYCHOLOGISCHE FORSCHUNG
(2020)
Article
Art
John Tchalenko, R. Chris Miall