Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells

Celecoxib synergizes human pancreatic ductal adenocarcinoma cells to sorafenib-induced growth inhibition

(2013) Ann H. Rosendahl et al.   PANCREATOLOGY

Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: Dependence on glucose concentration and role of AMPK

(2012) James Sinnett-Smith et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway

(2012) Luisa Garcia-Haro et al.   FEBS LETTERS

Diabetes mellitus, glycated haemoglobin and C-peptide levels in relation to pancreatic cancer risk: a study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

(2011) V. A. Grote et al.   DIABETOLOGIA

Suppression of AMPK Activation via S485 Phosphorylation by IGF-I during Hyperglycemia Is Mediated by AKT Activation in Vascular Smooth Muscle Cells

(2011) Junyu Ning et al.   ENDOCRINOLOGY

Metformin Induces Both Caspase-Dependent and Poly(ADP-ribose) Polymerase-Dependent Cell Death in Breast Cancer Cells

(2011) Y. Zhuang et al.   MOLECULAR CANCER RESEARCH

Diabetes Mellitus, Fasting Glucose, and Risk of Cause-Specific Death

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Diabetes and Pancreatic Cancer

(2011) J. Trent Magruder et al.   PANCREAS

Obesity related hyperinsulinaemia and hyperglycaemia and cancer development

(2011) Susen Becker et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells

(2010) Mahvash Zakikhani et al.   BREAST CANCER RESEARCH AND TREATMENT

Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis

(2010) A. DeCensi et al.   Cancer Prevention Research

Metformin Prevents Tobacco Carcinogen-Induced Lung Tumorigenesis

(2010) R. M. Memmott et al.   Cancer Prevention Research

New Strategies in Pancreatic Cancer: Emerging Epidemiologic and Therapeutic Concepts

(2010) D. Li et al.   CLINICAL CANCER RESEARCH

Metformin: A Therapeutic Opportunity in Breast Cancer

(2010) A. M. Gonzalez-Angulo et al.   CLINICAL CANCER RESEARCH

AMP-Activated Protein Kinase Inhibits IGF-I Signaling and Protein Synthesis in Vascular Smooth Muscle Cells via Stimulation of Insulin Receptor Substrate 1 S794 and Tuberous Sclerosis 2 S1345 Phosphorylation

(2010) Junyu Ning et al.   MOLECULAR ENDOCRINOLOGY

Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo

(2010) C Algire et al.   ONCOGENE

Diabetes Mellitus in Pancreatic Cancer and the Need for Diagnosis of Asymptomatic Disease

(2010) A. Bartosch-Härlid et al.   PANCREATOLOGY

The influence of glucose-lowering therapies on cancer risk in type 2 diabetes

(2009) C. J. Currie et al.   DIABETOLOGIA

Antidiabetic Therapies Affect Risk of Pancreatic Cancer

(2009) Donghui Li et al.   GASTROENTEROLOGY

New-onset diabetes: a potential clue to the early diagnosis of pancreatic cancer

(2008) Rahul Pannala et al.   LANCET ONCOLOGY

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

(2008) I Ben Sahra et al.   ONCOGENE

Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies

(2008) Paola Pisani   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY